ZA866258B - Gamma-carbolines - Google Patents

Gamma-carbolines

Info

Publication number
ZA866258B
ZA866258B ZA866258A ZA866258A ZA866258B ZA 866258 B ZA866258 B ZA 866258B ZA 866258 A ZA866258 A ZA 866258A ZA 866258 A ZA866258 A ZA 866258A ZA 866258 B ZA866258 B ZA 866258B
Authority
ZA
South Africa
Prior art keywords
carbolines
gamma
Prior art date
Application number
ZA866258A
Other languages
English (en)
Inventor
Magid Abdel-Megid Abou-Gharbia
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA866258B publication Critical patent/ZA866258B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA866258A 1985-09-16 1986-08-19 Gamma-carbolines ZA866258B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/776,180 US4636563A (en) 1985-09-16 1985-09-16 Antipsychotic γ-carbolines

Publications (1)

Publication Number Publication Date
ZA866258B true ZA866258B (en) 1988-04-27

Family

ID=25106686

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA866258A ZA866258B (en) 1985-09-16 1986-08-19 Gamma-carbolines

Country Status (28)

Country Link
US (1) US4636563A (es)
EP (1) EP0223344B1 (es)
JP (1) JPS6267083A (es)
KR (1) KR900002245B1 (es)
CN (1) CN1013864B (es)
AR (1) AR242208A1 (es)
AT (1) ATE55770T1 (es)
AU (1) AU590605B2 (es)
CA (1) CA1275099A (es)
CY (1) CY1595A (es)
DE (1) DE3673607D1 (es)
DK (1) DK440686A (es)
EG (1) EG18015A (es)
ES (1) ES2002656A6 (es)
FI (1) FI83318C (es)
GB (1) GB2180536B (es)
GR (1) GR862343B (es)
HK (1) HK53491A (es)
HU (1) HU195217B (es)
IL (1) IL79956A0 (es)
MX (1) MX3681A (es)
NO (1) NO163619C (es)
NZ (1) NZ217580A (es)
PH (1) PH22515A (es)
PT (1) PT83344B (es)
SU (1) SU1442074A3 (es)
YU (1) YU45023B (es)
ZA (1) ZA866258B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5328905A (en) * 1987-07-20 1994-07-12 Duphar International Research B.V. 8,9-anellated-1,2,3,4-tetrahydro-β-carboline derivatives
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
US5008272A (en) * 1988-08-15 1991-04-16 Glaxo Group Limited Lactam derivatives
US5021569A (en) * 1990-06-12 1991-06-04 American Home Products Corporation 4-azatricyclo[4.3.1.1(3,8)]undecylarylpiperazines with anxiolytic activity
US5484788A (en) * 1993-03-26 1996-01-16 Beth Israel Hospital Association Buspirone as a systemic immunosuppressant
US5631017A (en) * 1993-03-26 1997-05-20 Beth Israel Deaconess Medical Center, Inc. Topical application of buspirone for treatment of pathological conditions associated with immune responses
CN1109880A (zh) * 1994-02-03 1995-10-11 合成实验室公司 3-(2-氨基乙基)-4-[3-(三氟甲基)苯甲酰基]-3，4-二氢-2h-1，4-苯并噁嗪衍生物、制备及其应用
FR2715659B1 (fr) * 1994-02-03 1996-03-22 Synthelabo Dérivés de 3-(2-aminoéthyl)-4-[3-(trifluorométhyl)benzoyl]-3,4-dihydro-2H-1,4-benzoxazine, leur préparation et leur application en thérapeutique.
JP3274579B2 (ja) * 1995-01-12 2002-04-15 住友製薬株式会社 脳血管障害に伴う精神症候治療剤
US5637314A (en) * 1995-06-07 1997-06-10 Beth Israel Deaconess Medical Center, Inc. Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
RU2106864C1 (ru) * 1995-10-23 1998-03-20 Николай Серафимович Зефиров Средство для лечения болезни альцгеймера
RU2283108C2 (ru) * 2003-12-08 2006-09-10 Сергей Олегович Бачурин ГЕРОПРОТЕКТОР НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b) ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
US20070179174A1 (en) * 2003-12-08 2007-08-02 Bachurin Sergei O Methods and compositions for slowing aging
AU2006275694A1 (en) * 2005-07-28 2007-02-08 Bristol-Myers Squibb Company Substituted tetrahydro-1H-pyrido(4,3,b)indoles as serotonin receptor agonists and antagonists
US20070117835A1 (en) * 2005-10-04 2007-05-24 David Hung Methods and compositions for treating Huntington's disease
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670010A1 (de) * 1966-12-07 1970-07-30 Abbott Lab Aroylalkylderivate von 1,2,3,4-Tetrahydro-5H-pyride-[4,3b]-indolen und Verfahren zur Herstellung derselben
US3522262A (en) * 1968-09-10 1970-07-28 Hoffmann La Roche 5-(pyridylalkyl)-pyridoindole derivatives
US3502688A (en) * 1968-09-10 1970-03-24 Hoffmann La Roche 5-(4-pyridylethyl)-pyridoindole derivatives
DE1952800C3 (de) * 1969-10-20 1974-04-18 Nautschno-Issledowatelskij Institut Farmakologii I Chimioterapii, Moskau 3,6-Dimethyl-l,2,3,4,4a,9a-hexahydro-gamma-carbolin-dihydrochlorid
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
DE2621729A1 (de) * 1976-05-15 1977-12-08 Boehringer Sohn Ingelheim Neue 2-(4-phenyl-4-cyanobutyl)-1,2, 3,4-tetrahydro-5(h)-pyrido- eckige klammer auf 4,3-b eckige klammer zu -indole und verfahren zu ihrer herstellung
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
US4672117A (en) * 1985-09-16 1987-06-09 American Home Products Corporation Antipsychotic gamma-carbolines
DE3851597T2 (de) * 1987-09-03 1995-01-26 Glaxo Group Ltd., London Lactamderivate.

Also Published As

Publication number Publication date
NO863671L (no) 1987-03-17
KR900002245B1 (ko) 1990-04-07
HUT42478A (en) 1987-07-28
AU6181386A (en) 1987-03-19
EP0223344B1 (en) 1990-08-22
FI83318B (fi) 1991-03-15
CN86106194A (zh) 1987-03-18
GB8621226D0 (en) 1986-10-08
ES2002656A6 (es) 1988-09-16
JPS6267083A (ja) 1987-03-26
GB2180536A (en) 1987-04-01
ATE55770T1 (de) 1990-09-15
YU45023B (en) 1991-06-30
YU157686A (en) 1988-04-30
FI863692A (fi) 1987-03-17
KR870003103A (ko) 1987-04-15
EP0223344A1 (en) 1987-05-27
NO163619C (no) 1990-06-27
DK440686A (da) 1987-03-17
FI83318C (fi) 1991-06-25
HU195217B (en) 1988-04-28
GB2180536B (en) 1989-04-05
US4636563A (en) 1987-01-13
GR862343B (en) 1987-01-12
CY1595A (en) 1992-04-03
SU1442074A3 (ru) 1988-11-30
AU590605B2 (en) 1989-11-09
PT83344A (pt) 1986-10-01
HK53491A (en) 1991-07-19
DE3673607D1 (en) 1990-09-27
PT83344B (pt) 1988-07-29
NZ217580A (en) 1988-07-28
DK440686D0 (da) 1986-09-15
CA1275099A (en) 1990-10-09
MX3681A (es) 1993-10-01
NO863671D0 (no) 1986-09-15
EG18015A (en) 1991-08-30
IL79956A0 (en) 1986-12-31
FI863692A0 (fi) 1986-09-12
CN1013864B (zh) 1991-09-11
NO163619B (no) 1990-03-19
PH22515A (en) 1988-09-12
AR242208A1 (es) 1994-08-31

Similar Documents

Publication Publication Date Title
BG47969A1 (en) Cryoultrasonic skalpel
ZA866258B (en) Gamma-carbolines
AR242568A1 (es) Un procedimiento para la preparacion de compuestos derivados del 1-carboxi-3,4-metilendioxi-fenantreno-8-sustituido.
CA54057S (en) Mini-kiosk
CA54075S (en) Footbag
CA54277S (en) Footbag
CA54278S (en) Footbag
CS101685A1 (en) Zapojeni optickeho vysilace optoelektronickeho prenosoveho systemu
CS1010985A1 (en) Zapojeni zesilovace vychylovaciho proudu
CS111385A1 (en) Zpusob chlazeni horkeho cementarskeho slinku
CS1009285A1 (en) Vicerada kulickova klec
CS10785A1 (en) Autonomni stridac
CS107585A1 (en) Zpusob stabilizace vodneho roztoku kyanatanu alkalickeho kovu
CS105985A1 (en) Zpusob vyroby konstrukcniho tepelne izolacniho materialu
CS105185A1 (en) Kotva sendvicoveho panelu
CS104985A1 (en) Sendvicovy plosny stavebni prvek
CS104785A1 (en) Penetrometr
CS103885A1 (en) Dialkylestery kyseliny butandiovej
CS103585A1 (en) Sposob izolace zvieracieho albuminu
CS101785A1 (en) Ploche rotacni soupatko
CS1008585A1 (en) Regeneracni ohrivak
CS113185A1 (en) Odlucovac kapalnych aerosolu
CS1013585A1 (en) Ovladaci prevod mikrospinace
CS1012885A1 (en) Barvici koncentraty nebo barvici smssi
CS1012785A1 (en) Univerzalni mechanicka rezaci hlava