ZA865826B - Peptide derivatives having a lactone or cycloamide structure,process for the preparation thereof and pharmaceutical compositions containing them - Google Patents
Peptide derivatives having a lactone or cycloamide structure,process for the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- ZA865826B ZA865826B ZA865826A ZA865826A ZA865826B ZA 865826 B ZA865826 B ZA 865826B ZA 865826 A ZA865826 A ZA 865826A ZA 865826 A ZA865826 A ZA 865826A ZA 865826 B ZA865826 B ZA 865826B
- Authority
- ZA
- South Africa
- Prior art keywords
- cycloamide
- lactone
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- 150000002596 lactones Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- IVOMOUWHDPKRLL-KQYNXXCUSA-N Cyclic adenosine monophosphate Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-KQYNXXCUSA-N 0.000 abstract 1
- IVOMOUWHDPKRLL-UHFFFAOYSA-N UNPD107823 Natural products O1C2COP(O)(=O)OC2C(O)C1N1C(N=CN=C2N)=C2N=C1 IVOMOUWHDPKRLL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229940095074 cyclic amp Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000002503 metabolic effect Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8511936A FR2585709B1 (fr) | 1985-08-05 | 1985-08-05 | Nouveaux derives peptidiques a structure lactonique ou cycloamidique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA865826B true ZA865826B (en) | 1987-04-29 |
Family
ID=9321967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA865826A ZA865826B (en) | 1985-08-05 | 1986-08-04 | Peptide derivatives having a lactone or cycloamide structure,process for the preparation thereof and pharmaceutical compositions containing them |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4725581A (da) |
| EP (1) | EP0217688B1 (da) |
| JP (2) | JPS6233198A (da) |
| AT (1) | ATE56976T1 (da) |
| AU (1) | AU581599B2 (da) |
| CA (1) | CA1276397C (da) |
| DE (1) | DE3674525D1 (da) |
| DK (1) | DK364786A (da) |
| ES (1) | ES2000128A6 (da) |
| FR (1) | FR2585709B1 (da) |
| GR (1) | GR862059B (da) |
| IE (1) | IE58541B1 (da) |
| NZ (1) | NZ217079A (da) |
| PT (1) | PT83145B (da) |
| ZA (1) | ZA865826B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0696575B2 (ja) * | 1987-09-17 | 1994-11-30 | 三菱化成株式会社 | ４−アミノピリジン誘導体及びその酸付加塩 |
| GB2227658A (en) * | 1989-02-03 | 1990-08-08 | Cellana | Thyrotropin releasing hormone (trh) composition for enhancing immune function |
| FR2649110B1 (fr) * | 1989-06-29 | 1994-10-21 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2663336B1 (fr) * | 1990-06-18 | 1992-09-04 | Adir | Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| IT1242002B (it) * | 1990-10-03 | 1994-02-02 | Polifarma Spa | Composti con attivita' farmacologica antiipertensiva, analgesica, immunomodulante e antiinfiammatoria, che presentano nella molecola una sequenza di tre radicali, essendo alfa-amminoacido quello centrale |
| US5504071A (en) * | 1990-10-03 | 1996-04-02 | Polifarma S.P.A. | Compounds with a sequence of three radicals, the central one being α-a |
| FR2694295B1 (fr) * | 1992-07-28 | 1994-09-02 | Adir | Nouveaux peptides dérivés de trifluoromethylcetones, leur procéde de préparation et les compositions pharmaceutiques qui les contiennent. |
| JP2000505425A (ja) * | 1996-02-05 | 2000-05-09 | イーライ・リリー・アンド・カンパニー | Ｔｒｈを用いるベータ―アミロイドペプチドに関連する状態の処置方法 |
| DE19616509A1 (de) * | 1996-04-25 | 1998-01-15 | Asta Medica Ag | Neue spezifische Immunophilin-Liganden als Antiasthmatika, Immunsuppressiva |
| AU2003248584A1 (en) * | 2002-03-01 | 2003-09-16 | Warner-Lambert Company Llc | Method of treating osteoarthritis |
| US7628342B2 (en) | 2004-05-11 | 2009-12-08 | Daiwa Can Company | Liquefied gas dispensing nozzle and liquefied gas dispensing apparatus |
| EP1993527A4 (en) | 2006-01-26 | 2009-08-05 | Univ Rochester | INHIBITION OF AMYLOID BETA PEPTIDE / RAGE INTERACTION AT BLOOD BRAIN BARRIER |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5944308B2 (ja) * | 1976-03-23 | 1984-10-29 | 武田薬品工業株式会社 | ペプタイド |
| US4260601A (en) * | 1979-10-23 | 1981-04-07 | Nyegaard & Co. A/S | Chemical compounds |
| US4293481A (en) * | 1980-07-24 | 1981-10-06 | E. R. Squibb & Sons, Inc. | Tripeptide inhibitors of angiotensin-converting enzyme |
| JPS57188526A (en) * | 1981-05-14 | 1982-11-19 | Takeda Chem Ind Ltd | Peptide-containing pharmaceutical preparation |
| US4499079A (en) * | 1982-11-18 | 1985-02-12 | E. R. Squibb & Sons, Inc. | Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides |
| DE3332633A1 (de) * | 1983-09-09 | 1985-04-04 | Luitpold-Werk Chemisch-pharmazeutische Fabrik GmbH & Co, 8000 München | Substituierte carbonsaeurederivate, verfahren zu ihrer herstellung, und arzneimittel |
-
1985
- 1985-08-05 FR FR8511936A patent/FR2585709B1/fr not_active Expired
-
1986
- 1986-07-31 DK DK364786A patent/DK364786A/da not_active Application Discontinuation
- 1986-08-01 US US06/892,345 patent/US4725581A/en not_active Expired - Fee Related
- 1986-08-04 NZ NZ217079A patent/NZ217079A/en unknown
- 1986-08-04 EP EP86401738A patent/EP0217688B1/fr not_active Expired - Lifetime
- 1986-08-04 ZA ZA865826A patent/ZA865826B/xx unknown
- 1986-08-04 GR GR862059A patent/GR862059B/el unknown
- 1986-08-04 DE DE8686401738T patent/DE3674525D1/de not_active Expired - Lifetime
- 1986-08-04 ES ES8600846A patent/ES2000128A6/es not_active Expired
- 1986-08-04 CA CA000515267A patent/CA1276397C/fr not_active Expired - Lifetime
- 1986-08-04 AT AT86401738T patent/ATE56976T1/de not_active IP Right Cessation
- 1986-08-04 AU AU60812/86A patent/AU581599B2/en not_active Ceased
- 1986-08-05 PT PT83145A patent/PT83145B/pt not_active IP Right Cessation
- 1986-08-05 IE IE208586A patent/IE58541B1/en not_active IP Right Cessation
- 1986-08-05 JP JP61184117A patent/JPS6233198A/ja active Granted
-
1989
- 1989-01-05 JP JP64000815A patent/JPH01230597A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| AU6081286A (en) | 1987-02-12 |
| DK364786D0 (da) | 1986-07-31 |
| GR862059B (en) | 1986-12-24 |
| DK364786A (da) | 1987-02-06 |
| PT83145B (pt) | 1989-03-30 |
| IE58541B1 (en) | 1993-10-06 |
| IE862085L (en) | 1987-02-05 |
| JPH0259160B2 (da) | 1990-12-11 |
| EP0217688B1 (fr) | 1990-09-26 |
| ES2000128A6 (es) | 1987-12-16 |
| US4725581A (en) | 1988-02-16 |
| FR2585709A1 (fr) | 1987-02-06 |
| FR2585709B1 (fr) | 1987-10-02 |
| JPH0229680B2 (da) | 1990-07-02 |
| ATE56976T1 (de) | 1990-10-15 |
| NZ217079A (en) | 1988-05-30 |
| CA1276397C (fr) | 1990-11-13 |
| JPH01230597A (ja) | 1989-09-14 |
| EP0217688A1 (fr) | 1987-04-08 |
| PT83145A (fr) | 1986-09-01 |
| AU581599B2 (en) | 1989-02-23 |
| JPS6233198A (ja) | 1987-02-13 |
| DE3674525D1 (de) | 1990-10-31 |
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