ZA862183B - Benzo(alpha)phenazine derivatives - Google Patents
Benzo(alpha)phenazine derivativesInfo
- Publication number
- ZA862183B ZA862183B ZA862183A ZA862183A ZA862183B ZA 862183 B ZA862183 B ZA 862183B ZA 862183 A ZA862183 A ZA 862183A ZA 862183 A ZA862183 A ZA 862183A ZA 862183 B ZA862183 B ZA 862183B
- Authority
- ZA
- South Africa
- Prior art keywords
- sup
- sub
- hydrogen
- benzo
- phenazine derivatives
- Prior art date
Links
- 125000005605 benzo group Chemical group 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- SEXRCKWGFSXUOO-UHFFFAOYSA-N benzo[a]phenazine Chemical class C1=CC=C2N=C3C4=CC=CC=C4C=CC3=NC2=C1 SEXRCKWGFSXUOO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/46—Phenazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Luminescent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Fireproofing Substances (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6509985 | 1985-03-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA862183B true ZA862183B (en) | 1986-11-26 |
Family
ID=13277123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA862183A ZA862183B (en) | 1985-03-29 | 1986-03-24 | Benzo(alpha)phenazine derivatives |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4686292A (ja) |
| EP (1) | EP0196910B1 (ja) |
| JP (1) | JPS6272A (ja) |
| KR (1) | KR930002279B1 (ja) |
| AT (1) | ATE59642T1 (ja) |
| CA (1) | CA1248106A (ja) |
| DE (1) | DE3676333D1 (ja) |
| ES (1) | ES8706650A1 (ja) |
| ZA (1) | ZA862183B (ja) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6231894B1 (en) | 1999-10-21 | 2001-05-15 | Duke University | Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase |
| KR100441247B1 (ko) * | 2001-07-31 | 2004-07-21 | 학교법인 이화학당 | 피리도페나진다이온 유도체, 그의 제조방법 및 이를함유하는 항암제 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5959674A (ja) * | 1982-09-29 | 1984-04-05 | Taisho Pharmaceut Co Ltd | ベンゾ〔ａ〕フェナジン誘導体 |
-
1986
- 1986-03-10 US US06/838,153 patent/US4686292A/en not_active Expired - Fee Related
- 1986-03-18 CA CA000504378A patent/CA1248106A/en not_active Expired
- 1986-03-20 JP JP61064410A patent/JPS6272A/ja active Granted
- 1986-03-24 ZA ZA862183A patent/ZA862183B/xx unknown
- 1986-03-26 ES ES553500A patent/ES8706650A1/es not_active Expired
- 1986-03-28 KR KR1019860002313A patent/KR930002279B1/ko not_active IP Right Cessation
- 1986-04-01 DE DE8686302395T patent/DE3676333D1/de not_active Expired - Fee Related
- 1986-04-01 AT AT86302395T patent/ATE59642T1/de not_active IP Right Cessation
- 1986-04-01 EP EP86302395A patent/EP0196910B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| KR860007222A (ko) | 1986-10-08 |
| CA1248106A (en) | 1989-01-03 |
| EP0196910A3 (en) | 1987-09-02 |
| US4686292A (en) | 1987-08-11 |
| KR930002279B1 (ko) | 1993-03-27 |
| ES553500A0 (es) | 1987-06-16 |
| ATE59642T1 (de) | 1991-01-15 |
| JPH0513149B2 (ja) | 1993-02-19 |
| EP0196910A2 (en) | 1986-10-08 |
| JPS6272A (ja) | 1987-01-06 |
| EP0196910B1 (en) | 1991-01-02 |
| ES8706650A1 (es) | 1987-06-16 |
| DE3676333D1 (de) | 1991-02-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3066313D1 (en) | Imidazole derivatives, their production and use | |
| DE3677841D1 (de) | Diaminoandrostanderivate. | |
| MY129935A (en) | Dihydropyridine derivatives useful in antitumor therapy | |
| MY117092A (en) | Chemotherapeutic pyrrolocarbazole derivatives | |
| PT80553A (en) | Cephalosporin derivatives | |
| KR920701228A (ko) | 독소루비신의 모르폴리닐 유도체 및 이의 제조방법 | |
| GR852813B (ja) | ||
| ZA862183B (en) | Benzo(alpha)phenazine derivatives | |
| ZA831226B (en) | Novel derivatives of psoralen | |
| ES8707226A1 (es) | Procedimiento para preparar derivados de (dihidro-4, 5-1h-imidazolil-2)-2-didrido-2,3-indol | |
| FR2540870B1 (ja) | ||
| KR880009959A (ko) | 방향족 아민 유도체 | |
| DE69330693D1 (de) | Antitumor 5,8-Dihydrodiazaanthracene | |
| ES468585A1 (es) | Procedimiento para la preparacion de nuevas piridobenzodia- zepinonas. | |
| JO1676B1 (en) | Extra compounds indinol II | |
| DK145286D0 (da) | Bicyclooctanderivater | |
| ATE63537T1 (de) | Carbacyclin-derivate. | |
| DE3688128D1 (de) | Isoindolinderivate und verfahren zu ihrer herstellung. | |
| ATE56962T1 (de) | 3,4-disubstituierte-1,2,5-oxadiazole mit histamin h2-rezeptor-antagonisten-aktivitaet. | |
| TW357140B (en) | Substituted benzenesulfonylureas and -thioureas having cardiac activity, processes for their preparation, and the pharmaceutical compositions thereof | |
| GB8419278D0 (en) | Pharmaceutical compounds | |
| ES8701144A1 (es) | Un procedimiento para preparar un derivado de tetrahidronaf-taleno | |
| ATE44736T1 (de) | Ananas-keton-1'-alkoxyalkylderivate. | |
| BG102081A (en) | New derivatives of 2-azabicyclo [2.2.1] heptane, their preparation and application |