ZA861713B - B-lactam antibiotics,process for their preparation and their use as and in medicaments - Google Patents

B-lactam antibiotics,process for their preparation and their use as and in medicaments

Info

Publication number
ZA861713B
ZA861713B ZA861713A ZA861713A ZA861713B ZA 861713 B ZA861713 B ZA 861713B ZA 861713 A ZA861713 A ZA 861713A ZA 861713 A ZA861713 A ZA 861713A ZA 861713 B ZA861713 B ZA 861713B
Authority
ZA
South Africa
Prior art keywords
medicaments
preparation
lactam antibiotics
representing
image
Prior art date
Application number
ZA861713A
Other languages
English (en)
Inventor
Gunter Schmidt
Hans-Joachim Zeiler
Karl Georg Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA861713B publication Critical patent/ZA861713B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Fodder In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA861713A 1985-03-08 1986-03-07 B-lactam antibiotics,process for their preparation and their use as and in medicaments ZA861713B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853508258 DE3508258A1 (de) 1985-03-08 1985-03-08 Ss-lactamantibiotika, verfahren zur herstellung und ihre verwendung als und in arzneimitteln

Publications (1)

Publication Number Publication Date
ZA861713B true ZA861713B (en) 1986-11-26

Family

ID=6264592

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA861713A ZA861713B (en) 1985-03-08 1986-03-07 B-lactam antibiotics,process for their preparation and their use as and in medicaments

Country Status (20)

Country Link
US (2) US4748163A (ja)
EP (1) EP0195947B1 (ja)
JP (1) JPH0649708B2 (ja)
KR (1) KR930007420B1 (ja)
AT (1) ATE137238T1 (ja)
AU (1) AU594941B2 (ja)
CA (1) CA1281315C (ja)
DD (2) DD251751A5 (ja)
DE (2) DE3508258A1 (ja)
DK (1) DK105286A (ja)
ES (1) ES8800234A1 (ja)
FI (1) FI85708C (ja)
GR (1) GR860626B (ja)
HU (1) HU200183B (ja)
IE (1) IE860598L (ja)
IL (1) IL78042A0 (ja)
NO (1) NO165108C (ja)
PH (1) PH24000A (ja)
PT (1) PT82143B (ja)
ZA (1) ZA861713B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3509618A1 (de) * 1985-03-16 1986-09-18 Bayer Ag, 5090 Leverkusen Ss-lactam-antibiotika, verfahren zur herstellung und ihre verwendung als arzneimittel
AU637400B2 (en) * 1987-05-26 1993-05-27 Bayer Aktiengesellschaft Substituted vinylcephalosporins, processes for their preparation and their use as medicaments
DE3734004A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3734005A1 (de) * 1987-05-26 1988-12-15 Bayer Ag Substituierte vinylcephalosporine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5171854A (en) * 1987-05-26 1992-12-15 Bayer Aktiengesellschaft Substituted vinylcephalosporins
DE3733626A1 (de) * 1987-10-05 1989-04-13 Bayer Ag Heteroanellierte phenylglycin-(beta)-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3803169A1 (de) * 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln
DE69331576T2 (de) * 1992-09-18 2002-10-17 Otsuka Kagaku K.K., Osaka Cephem-verbindungen, verfarhren zu ihrer herstellung und diese enthaltende medikamente
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
CA2495248A1 (en) 2002-08-30 2004-03-11 Memory Pharmaceuticals Corporation Anabaseine derivatives useful in the treatment of neurodegenerative diseases
ES2373469T3 (es) * 2006-05-31 2012-02-03 Toyama Chemical Co., Ltd. Agente contra el virus de la glosopeda para un animal que pertenece a la familia suidae o de los ovinos, y método para la prevención o tratamiento de glosopeda en un animal que pertenece a la familia suidae o de los ovinos.
EP2935253B1 (en) 2012-12-21 2018-08-01 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
JP6599852B2 (ja) * 2013-06-21 2019-10-30 ゼニス・エピジェネティクス・リミテッド ブロモドメイン阻害剤としての新規の置換された二環式化合物
ES2806135T3 (es) 2013-06-21 2021-02-16 Zenith Epigenetics Ltd Nuevos inhibidores de bromodominios bicíclicos
CN105593224B (zh) 2013-07-31 2021-05-25 恒元生物医药科技(苏州)有限公司 作为溴结构域抑制剂的新型喹唑啉酮类化合物
CA2966298A1 (en) 2014-12-01 2016-06-09 Zenith Epigenetics Ltd. Substituted pyridinones as bromodomain inhibitors
US10179125B2 (en) 2014-12-01 2019-01-15 Zenith Epigenetics Ltd. Substituted pyridines as bromodomain inhibitors
JP2017537946A (ja) 2014-12-11 2017-12-21 ゼニス・エピジェネティクス・リミテッドＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｌｔｄ． ブロモドメイン阻害剤としての置換複素環
CA2966450A1 (en) 2014-12-17 2016-06-23 Olesya KHARENKO Inhibitors of bromodomains

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080356A (en) * 1960-06-15 1963-03-05 Beecham Res Lab Process for the production of synthetic penicillins
SE302125B (ja) * 1961-03-23 1968-07-08 Bristol Myers Co
GB1174335A (en) * 1967-03-07 1969-12-17 Lilly Co Eli 7-Alpha-Amino-3-Methyl Cephalosporin Analogues, Pharmaceutical Compositions comprising the same and processes for preparing the same
YU36970B (en) * 1973-02-23 1984-08-31 Lilly Co Eli Process for obtaining 7-(amino)-acylamido-3-halocephalosporins
IL52144A (en) * 1976-07-01 1979-10-31 Lilly Co Eli De-esterification process for -lactam antibiotic esters
DE2831568C2 (de) * 1977-07-23 1985-01-10 Toyama Chemical Co. Ltd., Tokio / Tokyo 7α-Methoxycephalosporine und Verfahren zur Herstellung derselben
US4138397A (en) * 1978-02-27 1979-02-06 Richardson-Merrell Inc. 6-(2,3-Dihydro-5-benzofuranyl)acetamido penicillin derivatives
US4229575A (en) * 1978-02-27 1980-10-21 Richardson-Merrell Inc. 7-(2,3-Dihydrobenzo-5-furanyl)-acetamido cephalosporin derivatives
US4219648A (en) * 1978-03-06 1980-08-26 Richardson-Merrell Inc. 7-[[Amino(1,3-dihydrobenzo[c]thienyl)acetyl]amino]cephalosporin derivatives
US4461767A (en) * 1978-06-16 1984-07-24 E. R. Squibb & Sons, Inc. Iminothiazolyl ureido cephalosporins
US4317775A (en) * 1980-01-07 1982-03-02 Hoffmann-La Roche Inc. Amoxicillin derivatives
FR2511375A1 (fr) * 1981-08-17 1983-02-18 Rhone Poulenc Sante Nouveaux derives de la cephalosporine, leur preparation et les medicaments qui les contiennent
AU1294383A (en) * 1982-03-31 1983-10-06 Beecham Group Plc Beta lactam antibiotics
US4501741A (en) * 1983-04-12 1985-02-26 Eli Lilly And Company Cephalosporin antibiotics

Also Published As

Publication number Publication date
FI85708C (fi) 1992-05-25
GR860626B (en) 1986-07-07
ES552683A0 (es) 1987-11-01
PT82143B (pt) 1988-07-29
ES8800234A1 (es) 1987-11-01
USRE33948E (en) 1992-06-02
DK105286A (da) 1986-09-09
ATE137238T1 (de) 1996-05-15
HUT41031A (en) 1987-03-30
PT82143A (en) 1986-04-01
US4748163A (en) 1988-05-31
PH24000A (en) 1990-02-09
FI85708B (fi) 1992-02-14
KR860007265A (ko) 1986-10-10
NO860679L (no) 1986-09-09
DD251751A5 (de) 1987-11-25
AU5443086A (en) 1986-09-11
JPH0649708B2 (ja) 1994-06-29
FI860945A0 (fi) 1986-03-06
DK105286D0 (da) 1986-03-07
HU200183B (en) 1990-04-28
AU594941B2 (en) 1990-03-22
IE860598L (en) 1986-09-08
FI860945A (fi) 1986-09-09
DE3508258A1 (de) 1986-09-18
NO165108C (no) 1990-12-27
CA1281315C (en) 1991-03-12
EP0195947B1 (de) 1996-04-24
KR930007420B1 (ko) 1993-08-10
EP0195947A2 (de) 1986-10-01
IL78042A0 (en) 1986-07-31
EP0195947A3 (en) 1988-05-04
DE3650518D1 (de) 1996-05-30
JPS61207388A (ja) 1986-09-13
NO165108B (no) 1990-09-17
DD266502A5 (de) 1989-04-05

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