ZA856907B - 4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl)amino)-3-furancarboxylic acids and derivatives thereof - Google Patents

4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl)amino)-3-furancarboxylic acids and derivatives thereof

Info

Publication number
ZA856907B
ZA856907B ZA856907A ZA856907A ZA856907B ZA 856907 B ZA856907 B ZA 856907B ZA 856907 A ZA856907 A ZA 856907A ZA 856907 A ZA856907 A ZA 856907A ZA 856907 B ZA856907 B ZA 856907B
Authority
ZA
South Africa
Prior art keywords
oxo
derivatives
amino
phenylcyclopropyl
trans
Prior art date
Application number
ZA856907A
Other languages
English (en)
Inventor
Vassil Stefanov Georgiev
Robert Alan Mack
Clyde Richard Kinsolving
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of ZA856907B publication Critical patent/ZA856907B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA856907A 1984-09-24 1985-09-10 4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl)amino)-3-furancarboxylic acids and derivatives thereof ZA856907B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/653,254 US4614810A (en) 1984-09-24 1984-09-24 4,5-dihydro-4-oxo-2-[(2-trans-phenylcyclopropyl)amino]-3-furancarboxylic acids and derivatives thereof

Publications (1)

Publication Number Publication Date
ZA856907B true ZA856907B (en) 1987-03-25

Family

ID=24620098

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA856907A ZA856907B (en) 1984-09-24 1985-09-10 4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl)amino)-3-furancarboxylic acids and derivatives thereof

Country Status (15)

Country Link
US (1) US4614810A (de)
EP (1) EP0179254B1 (de)
JP (1) JPS6178778A (de)
KR (1) KR860002489A (de)
AT (1) ATE41773T1 (de)
AU (1) AU570572B2 (de)
CA (1) CA1240687A (de)
DE (1) DE3569112D1 (de)
DK (1) DK429585A (de)
FI (1) FI853648A7 (de)
IL (1) IL76194A (de)
NO (1) NO853737L (de)
NZ (1) NZ213190A (de)
PH (1) PH21253A (de)
ZA (1) ZA856907B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY106163A (en) * 1990-03-26 1995-03-31 Schering Corp Bcrf1 antagonists for treating epstein-barr virus infections.
US7186735B2 (en) * 2002-08-07 2007-03-06 Sanofi-Aventis Deutschland Gmbh Acylated arylcycloalkylamines and their use as pharmaceuticals
EP1388535A1 (de) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylierte Arylcycloalkylamine und ihre Anwendung als Arzneimittelwirkstoff
ME03654B (de) 2014-02-13 2020-07-20 Incyte Corp Cyclopropylamine als lsd1-hemmer
TW201613860A (en) 2014-02-13 2016-04-16 Incyte Corp Cyclopropylamines as LSD1 inhibitors
PT3105226T (pt) 2014-02-13 2019-11-06 Incyte Corp Ciclopropilaminas como inibidores de lsd1
WO2015123437A1 (en) 2014-02-13 2015-08-20 Incyte Corporation Cyclopropylamines as lsd1 inhibitors
WO2016007731A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Imidazopyridines and imidazopyrazines as lsd1 inhibitors
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
AU2016243939B2 (en) 2015-04-03 2020-09-03 Incyte Holdings Corporation Heterocyclic compounds as LSD1 inhibitors
KR102710120B1 (ko) 2015-08-12 2024-09-27 인사이트 홀딩스 코포레이션 Lsd1 저해제의 염
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1210848A (en) * 1968-07-01 1970-11-04 Mcneilab Inc 2-imino-methyleneimines
US4244958A (en) * 1979-05-10 1981-01-13 American Home Products Corporation Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid
DE3301107A1 (de) * 1983-01-14 1984-07-19 Ozaki, Shoichiro, Ehime Neue 1-(n-substituierte carbamoyl)-5-fluorouracil-derivate und krebshemmende mittel, in denen sie als aktive bestandteile enthalten sind

Also Published As

Publication number Publication date
KR860002489A (ko) 1986-04-26
CA1240687A (en) 1988-08-16
ATE41773T1 (de) 1989-04-15
FI853648L (fi) 1986-03-25
DE3569112D1 (en) 1989-05-03
US4614810A (en) 1986-09-30
JPS6178778A (ja) 1986-04-22
PH21253A (en) 1987-08-31
FI853648A0 (fi) 1985-09-23
AU570572B2 (en) 1988-03-17
DK429585A (da) 1986-03-25
IL76194A0 (en) 1985-12-31
EP0179254B1 (de) 1989-03-29
IL76194A (en) 1988-06-30
EP0179254A1 (de) 1986-04-30
DK429585D0 (da) 1985-09-23
NZ213190A (en) 1988-04-29
NO853737L (no) 1986-03-25
FI853648A7 (fi) 1986-03-25
AU4629885A (en) 1986-04-10

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