IL76194A - 4,5-dihydro-4-oxo-2-((2-trans-phenyl cyclopropyl)amino)-3-furancarboxylic acids and derivatives - Google Patents

4,5-dihydro-4-oxo-2-((2-trans-phenyl cyclopropyl)amino)-3-furancarboxylic acids and derivatives

Info

Publication number
IL76194A
IL76194A IL76194A IL7619485A IL76194A IL 76194 A IL76194 A IL 76194A IL 76194 A IL76194 A IL 76194A IL 7619485 A IL7619485 A IL 7619485A IL 76194 A IL76194 A IL 76194A
Authority
IL
Israel
Prior art keywords
oxo
derivatives
amino
trans
dihydro
Prior art date
Application number
IL76194A
Other languages
English (en)
Other versions
IL76194A0 (en
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of IL76194A0 publication Critical patent/IL76194A0/xx
Publication of IL76194A publication Critical patent/IL76194A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL76194A 1984-09-24 1985-08-26 4,5-dihydro-4-oxo-2-((2-trans-phenyl cyclopropyl)amino)-3-furancarboxylic acids and derivatives IL76194A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/653,254 US4614810A (en) 1984-09-24 1984-09-24 4,5-dihydro-4-oxo-2-[(2-trans-phenylcyclopropyl)amino]-3-furancarboxylic acids and derivatives thereof

Publications (2)

Publication Number Publication Date
IL76194A0 IL76194A0 (en) 1985-12-31
IL76194A true IL76194A (en) 1988-06-30

Family

ID=24620098

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76194A IL76194A (en) 1984-09-24 1985-08-26 4,5-dihydro-4-oxo-2-((2-trans-phenyl cyclopropyl)amino)-3-furancarboxylic acids and derivatives

Country Status (15)

Country Link
US (1) US4614810A (de)
EP (1) EP0179254B1 (de)
JP (1) JPS6178778A (de)
KR (1) KR860002489A (de)
AT (1) ATE41773T1 (de)
AU (1) AU570572B2 (de)
CA (1) CA1240687A (de)
DE (1) DE3569112D1 (de)
DK (1) DK429585A (de)
FI (1) FI853648L (de)
IL (1) IL76194A (de)
NO (1) NO853737L (de)
NZ (1) NZ213190A (de)
PH (1) PH21253A (de)
ZA (1) ZA856907B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA912138B (en) * 1990-03-26 1991-12-24 Schering Corp Bcrf1 antagonists for treating epstein-barr virus infections
US7186735B2 (en) * 2002-08-07 2007-03-06 Sanofi-Aventis Deutschland Gmbh Acylated arylcycloalkylamines and their use as pharmaceuticals
EP1388535A1 (de) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylierte Arylcycloalkylamine und ihre Anwendung als Arzneimittelwirkstoff
TWI720451B (zh) 2014-02-13 2021-03-01 美商英塞特控股公司 作為lsd1抑制劑之環丙胺
KR102421235B1 (ko) * 2014-02-13 2022-07-15 인사이트 코포레이션 Lsd1 저해제로서 사이클로프로필아민
US9493442B2 (en) 2014-02-13 2016-11-15 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
US9527835B2 (en) 2014-02-13 2016-12-27 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
TWI687419B (zh) 2014-07-10 2020-03-11 美商英塞特公司 作為lsd1抑制劑之咪唑并吡啶及咪唑并吡嗪
TW201613925A (en) 2014-07-10 2016-04-16 Incyte Corp Imidazopyrazines as LSD1 inhibitors
WO2016007722A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Triazolopyridines and triazolopyrazines as lsd1 inhibitors
SG11201708047UA (en) 2015-04-03 2017-10-30 Incyte Corp Heterocyclic compounds as lsd1 inhibitors
CN110402244B (zh) 2015-08-12 2023-02-03 因赛特公司 Lsd1抑制剂的盐
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1210848A (en) * 1968-07-01 1970-11-04 Mcneilab Inc 2-imino-methyleneimines
US4244958A (en) * 1979-05-10 1981-01-13 American Home Products Corporation Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid
DE3301107A1 (de) * 1983-01-14 1984-07-19 Ozaki, Shoichiro, Ehime Neue 1-(n-substituierte carbamoyl)-5-fluorouracil-derivate und krebshemmende mittel, in denen sie als aktive bestandteile enthalten sind

Also Published As

Publication number Publication date
DK429585D0 (da) 1985-09-23
ZA856907B (en) 1987-03-25
AU570572B2 (en) 1988-03-17
IL76194A0 (en) 1985-12-31
EP0179254A1 (de) 1986-04-30
DK429585A (da) 1986-03-25
FI853648A7 (fi) 1986-03-25
DE3569112D1 (en) 1989-05-03
CA1240687A (en) 1988-08-16
NO853737L (no) 1986-03-25
EP0179254B1 (de) 1989-03-29
JPS6178778A (ja) 1986-04-22
NZ213190A (en) 1988-04-29
AU4629885A (en) 1986-04-10
ATE41773T1 (de) 1989-04-15
FI853648L (fi) 1986-03-25
US4614810A (en) 1986-09-30
PH21253A (en) 1987-08-31
KR860002489A (ko) 1986-04-26
FI853648A0 (fi) 1985-09-23

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