FI853648A0 - Foerfarande foer framstaellning av farmaceutiskt aktiva 4,5-dihydro-4-okso-2-/(2-trans-fenylcyklopropyl) amino/-3-furankarboxylsyror och derivat daerav. - Google Patents

Foerfarande foer framstaellning av farmaceutiskt aktiva 4,5-dihydro-4-okso-2-/(2-trans-fenylcyklopropyl) amino/-3-furankarboxylsyror och derivat daerav.

Info

Publication number
FI853648A0
FI853648A0 FI853648A FI853648A FI853648A0 FI 853648 A0 FI853648 A0 FI 853648A0 FI 853648 A FI853648 A FI 853648A FI 853648 A FI853648 A FI 853648A FI 853648 A0 FI853648 A0 FI 853648A0
Authority
FI
Finland
Prior art keywords
oxo
derivatives
amino
trans
furankarboxylsyror
Prior art date
Application number
FI853648A
Other languages
English (en)
Other versions
FI853648L (fi
Inventor
Vassil Stefano Georgiev
Robert Allan Mack
Clyde Richard Kinsolving
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of FI853648A0 publication Critical patent/FI853648A0/fi
Publication of FI853648L publication Critical patent/FI853648L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI853648A 1984-09-24 1985-09-23 Foerfarande foer framstaellning av farmaceutiskt aktiva 4,5-dihydro-4-okso-2-/(2-trans-fenylcyklopropyl) amino/-3-furankarboxylsyror och derivat daerav. FI853648L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/653,254 US4614810A (en) 1984-09-24 1984-09-24 4,5-dihydro-4-oxo-2-[(2-trans-phenylcyclopropyl)amino]-3-furancarboxylic acids and derivatives thereof

Publications (2)

Publication Number Publication Date
FI853648A0 true FI853648A0 (fi) 1985-09-23
FI853648L FI853648L (fi) 1986-03-25

Family

ID=24620098

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853648A FI853648L (fi) 1984-09-24 1985-09-23 Foerfarande foer framstaellning av farmaceutiskt aktiva 4,5-dihydro-4-okso-2-/(2-trans-fenylcyklopropyl) amino/-3-furankarboxylsyror och derivat daerav.

Country Status (15)

Country Link
US (1) US4614810A (fi)
EP (1) EP0179254B1 (fi)
JP (1) JPS6178778A (fi)
KR (1) KR860002489A (fi)
AT (1) ATE41773T1 (fi)
AU (1) AU570572B2 (fi)
CA (1) CA1240687A (fi)
DE (1) DE3569112D1 (fi)
DK (1) DK429585A (fi)
FI (1) FI853648L (fi)
IL (1) IL76194A (fi)
NO (1) NO853737L (fi)
NZ (1) NZ213190A (fi)
PH (1) PH21253A (fi)
ZA (1) ZA856907B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY106163A (en) * 1990-03-26 1995-03-31 Schering Corp Bcrf1 antagonists for treating epstein-barr virus infections.
EP1388535A1 (en) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Acylated arylcycloalkylamines and their use as pharmaceuticals
US7186735B2 (en) * 2002-08-07 2007-03-06 Sanofi-Aventis Deutschland Gmbh Acylated arylcycloalkylamines and their use as pharmaceuticals
TWI720451B (zh) 2014-02-13 2021-03-01 美商英塞特控股公司 作為lsd1抑制劑之環丙胺
WO2015123437A1 (en) 2014-02-13 2015-08-20 Incyte Corporation Cyclopropylamines as lsd1 inhibitors
US9670210B2 (en) 2014-02-13 2017-06-06 Incyte Corporation Cyclopropylamines as LSD1 inhibitors
EP3392244A1 (en) 2014-02-13 2018-10-24 Incyte Corporation Cyclopropylamines as lsd1 inhibitors
US9695167B2 (en) 2014-07-10 2017-07-04 Incyte Corporation Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors
WO2016007736A1 (en) 2014-07-10 2016-01-14 Incyte Corporation Imidazopyrazines as lsd1 inhibitors
TWI687419B (zh) 2014-07-10 2020-03-11 美商英塞特公司 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪
EA201792205A1 (ru) 2015-04-03 2018-02-28 Инсайт Корпорейшн Гетероциклические соединения как ингибиторы lsd1
AU2016306555B2 (en) 2015-08-12 2021-01-28 Incyte Holdings Corporation Salts of an LSD1 inhibitor
WO2020047198A1 (en) 2018-08-31 2020-03-05 Incyte Corporation Salts of an lsd1 inhibitor and processes for preparing the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1210848A (en) * 1968-07-01 1970-11-04 Mcneilab Inc 2-imino-methyleneimines
US4244958A (en) * 1979-05-10 1981-01-13 American Home Products Corporation Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid
DE3301107A1 (de) * 1983-01-14 1984-07-19 Ozaki, Shoichiro, Ehime Neue 1-(n-substituierte carbamoyl)-5-fluorouracil-derivate und krebshemmende mittel, in denen sie als aktive bestandteile enthalten sind

Also Published As

Publication number Publication date
AU570572B2 (en) 1988-03-17
ATE41773T1 (de) 1989-04-15
ZA856907B (en) 1987-03-25
EP0179254A1 (en) 1986-04-30
IL76194A0 (en) 1985-12-31
DE3569112D1 (en) 1989-05-03
FI853648L (fi) 1986-03-25
EP0179254B1 (en) 1989-03-29
JPS6178778A (ja) 1986-04-22
IL76194A (en) 1988-06-30
AU4629885A (en) 1986-04-10
NO853737L (no) 1986-03-25
KR860002489A (ko) 1986-04-26
CA1240687A (en) 1988-08-16
DK429585D0 (da) 1985-09-23
US4614810A (en) 1986-09-30
NZ213190A (en) 1988-04-29
DK429585A (da) 1986-03-25
PH21253A (en) 1987-08-31

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Legal Events

Date Code Title Description
FA Application withdrawn

Owner name: PENNWALT CORPORATION