ZA856907B - 4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl)amino)-3-furancarboxylic acids and derivatives thereof - Google Patents
4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl)amino)-3-furancarboxylic acids and derivatives thereofInfo
- Publication number
- ZA856907B ZA856907B ZA856907A ZA856907A ZA856907B ZA 856907 B ZA856907 B ZA 856907B ZA 856907 A ZA856907 A ZA 856907A ZA 856907 A ZA856907 A ZA 856907A ZA 856907 B ZA856907 B ZA 856907B
- Authority
- ZA
- South Africa
- Prior art keywords
- oxo
- derivatives
- amino
- phenylcyclopropyl
- trans
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/653,254 US4614810A (en) | 1984-09-24 | 1984-09-24 | 4,5-dihydro-4-oxo-2-[(2-trans-phenylcyclopropyl)amino]-3-furancarboxylic acids and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA856907B true ZA856907B (en) | 1987-03-25 |
Family
ID=24620098
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA856907A ZA856907B (en) | 1984-09-24 | 1985-09-10 | 4,5-dihydro-4-oxo-2-((2-trans-phenylcyclopropyl)amino)-3-furancarboxylic acids and derivatives thereof |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4614810A (xx) |
| EP (1) | EP0179254B1 (xx) |
| JP (1) | JPS6178778A (xx) |
| KR (1) | KR860002489A (xx) |
| AT (1) | ATE41773T1 (xx) |
| AU (1) | AU570572B2 (xx) |
| CA (1) | CA1240687A (xx) |
| DE (1) | DE3569112D1 (xx) |
| DK (1) | DK429585A (xx) |
| FI (1) | FI853648L (xx) |
| IL (1) | IL76194A (xx) |
| NO (1) | NO853737L (xx) |
| NZ (1) | NZ213190A (xx) |
| PH (1) | PH21253A (xx) |
| ZA (1) | ZA856907B (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL97629A0 (en) * | 1990-03-26 | 1992-06-21 | Schering Corp | Bcrf1 antagonists for treating epstein-barr virus infections |
| EP1388535A1 (en) * | 2002-08-07 | 2004-02-11 | Aventis Pharma Deutschland GmbH | Acylated arylcycloalkylamines and their use as pharmaceuticals |
| US7186735B2 (en) * | 2002-08-07 | 2007-03-06 | Sanofi-Aventis Deutschland Gmbh | Acylated arylcycloalkylamines and their use as pharmaceuticals |
| SG10201806849WA (en) * | 2014-02-13 | 2018-09-27 | Incyte Corp | Cyclopropylamines as lsd1 inhibitors |
| TWI664164B (zh) | 2014-02-13 | 2019-07-01 | 美商英塞特控股公司 | 作為ｌｓｄ１抑制劑之環丙胺 |
| WO2015123437A1 (en) | 2014-02-13 | 2015-08-20 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| EP3105219B9 (en) | 2014-02-13 | 2018-10-03 | Incyte Corporation | Cyclopropylamines as lsd1 inhibitors |
| US9695180B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted imidazo[1,2-a]pyrazines as LSD1 inhibitors |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪 |
| JP6995623B2 (ja) | 2015-04-03 | 2022-01-14 | インサイト・コーポレイション | Ｌｓｄ１阻害剤としてのヘテロ環式化合物 |
| TWI765860B (zh) | 2015-08-12 | 2022-06-01 | 美商英塞特公司 | Lsd1抑制劑之鹽 |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1210848A (en) * | 1968-07-01 | 1970-11-04 | Mcneilab Inc | 2-imino-methyleneimines |
| US4244958A (en) * | 1979-05-10 | 1981-01-13 | American Home Products Corporation | Hypolipidemic derivatives of 4,5-dihydro-4-oxofuran-2-carboxylic acid |
| DE3301107A1 (de) * | 1983-01-14 | 1984-07-19 | Ozaki, Shoichiro, Ehime | Neue 1-(n-substituierte carbamoyl)-5-fluorouracil-derivate und krebshemmende mittel, in denen sie als aktive bestandteile enthalten sind |
-
1984
- 1984-09-24 US US06/653,254 patent/US4614810A/en not_active Expired - Fee Related
-
1985
- 1985-08-14 CA CA000488712A patent/CA1240687A/en not_active Expired
- 1985-08-19 AU AU46298/85A patent/AU570572B2/en not_active Ceased
- 1985-08-21 NZ NZ213190A patent/NZ213190A/en unknown
- 1985-08-23 PH PH32682A patent/PH21253A/en unknown
- 1985-08-26 IL IL76194A patent/IL76194A/xx unknown
- 1985-09-10 ZA ZA856907A patent/ZA856907B/xx unknown
- 1985-09-13 EP EP85111574A patent/EP0179254B1/en not_active Expired
- 1985-09-13 AT AT85111574T patent/ATE41773T1/de active
- 1985-09-13 DE DE8585111574T patent/DE3569112D1/de not_active Expired
- 1985-09-17 JP JP60203591A patent/JPS6178778A/ja active Pending
- 1985-09-23 DK DK429585A patent/DK429585A/da not_active Application Discontinuation
- 1985-09-23 FI FI853648A patent/FI853648L/fi not_active Application Discontinuation
- 1985-09-23 NO NO853737A patent/NO853737L/no unknown
- 1985-09-24 KR KR1019850006996A patent/KR860002489A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO853737L (no) | 1986-03-25 |
| CA1240687A (en) | 1988-08-16 |
| DK429585A (da) | 1986-03-25 |
| EP0179254B1 (en) | 1989-03-29 |
| JPS6178778A (ja) | 1986-04-22 |
| AU570572B2 (en) | 1988-03-17 |
| AU4629885A (en) | 1986-04-10 |
| DE3569112D1 (en) | 1989-05-03 |
| DK429585D0 (da) | 1985-09-23 |
| KR860002489A (ko) | 1986-04-26 |
| NZ213190A (en) | 1988-04-29 |
| FI853648L (fi) | 1986-03-25 |
| US4614810A (en) | 1986-09-30 |
| PH21253A (en) | 1987-08-31 |
| IL76194A (en) | 1988-06-30 |
| ATE41773T1 (de) | 1989-04-15 |
| IL76194A0 (en) | 1985-12-31 |
| EP0179254A1 (en) | 1986-04-30 |
| FI853648A0 (fi) | 1985-09-23 |
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