ZA854877B - 4h-pyrimido(2,1a)isoquinolin-4-one derivatives - Google Patents

4h-pyrimido(2,1a)isoquinolin-4-one derivatives

Info

Publication number
ZA854877B
ZA854877B ZA854877A ZA854877A ZA854877B ZA 854877 B ZA854877 B ZA 854877B ZA 854877 A ZA854877 A ZA 854877A ZA 854877 A ZA854877 A ZA 854877A ZA 854877 B ZA854877 B ZA 854877B
Authority
ZA
South Africa
Prior art keywords
pyrimido
isoquinolin
derivatives
Prior art date
Application number
ZA854877A
Other languages
English (en)
Inventor
Arthur Lee Campbell
Suzanne Evans Radak
Melanie Jane Loots
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of ZA854877B publication Critical patent/ZA854877B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA854877A 1984-06-27 1985-06-27 4h-pyrimido(2,1a)isoquinolin-4-one derivatives ZA854877B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/625,061 US4661592A (en) 1984-06-27 1984-06-27 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives

Publications (1)

Publication Number Publication Date
ZA854877B true ZA854877B (en) 1986-08-27

Family

ID=24504413

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA854877A ZA854877B (en) 1984-06-27 1985-06-27 4h-pyrimido(2,1a)isoquinolin-4-one derivatives

Country Status (7)

Country Link
US (1) US4661592A (xx)
EP (1) EP0166439B1 (xx)
JP (1) JPS6124593A (xx)
AU (1) AU4417985A (xx)
DE (1) DE3577559D1 (xx)
ES (2) ES8703872A1 (xx)
ZA (1) ZA854877B (xx)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
JPH0619904Y2 (ja) * 1988-09-16 1994-05-25 株式会社クボタ 管継手
JPH0726632Y2 (ja) * 1990-09-28 1995-06-14 徳厚 小島 管継手
WO2008148074A2 (en) * 2007-05-24 2008-12-04 Research Foundation Of State University Of New York Inhibitors of mtor and methods of treatment using same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU168014B (xx) * 1973-03-30 1976-02-28
US4127720A (en) * 1977-09-21 1978-11-28 Bristol-Myers Company Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity
US4348396A (en) * 1978-01-23 1982-09-07 Hoffmann-La Roche Inc. Substituted 11-oxo-11H-pyrido[2,1-b]quinazolines and method of inhibiting allergic reactions with them
JPS59172490A (ja) * 1983-03-18 1984-09-29 Fujisawa Pharmaceut Co Ltd ピリミドイソキノリン誘導体およびその塩類、それらの製造法ならびにそれらを有効成分とする抗アレルギ−剤
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.

Also Published As

Publication number Publication date
JPS6124593A (ja) 1986-02-03
AU4417985A (en) 1986-01-02
ES557171A0 (es) 1988-01-01
US4661592A (en) 1987-04-28
DE3577559D1 (de) 1990-06-13
EP0166439A2 (en) 1986-01-02
EP0166439A3 (en) 1987-05-20
ES8801267A1 (es) 1988-01-01
ES8703872A1 (es) 1987-03-01
EP0166439B1 (en) 1990-05-09
ES544581A0 (es) 1987-03-01

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