ZA852803B - Purification of monoclonal antibodies - Google Patents

Purification of monoclonal antibodies

Info

Publication number
ZA852803B
ZA852803B ZA852803A ZA852803A ZA852803B ZA 852803 B ZA852803 B ZA 852803B ZA 852803 A ZA852803 A ZA 852803A ZA 852803 A ZA852803 A ZA 852803A ZA 852803 B ZA852803 B ZA 852803B
Authority
ZA
South Africa
Prior art keywords
purification
monoclonal antibodies
silica gel
monoclonal antibody
ascites fluid
Prior art date
Application number
ZA852803A
Other languages
English (en)
Inventor
Michael Flashner
Original Assignee
Baker Chem Co J T
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baker Chem Co J T filed Critical Baker Chem Co J T
Publication of ZA852803B publication Critical patent/ZA852803B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/806—Drug, bio-affecting and body treating compositions involving IgM
    • Y10S424/807—Monoclonal
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/863—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving IgM
    • Y10S530/864—Monoclonal

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
ZA852803A 1984-05-23 1985-04-15 Purification of monoclonal antibodies ZA852803B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/613,248 US4604235A (en) 1984-05-23 1984-05-23 Purification of monoclonal antibodies

Publications (1)

Publication Number Publication Date
ZA852803B true ZA852803B (en) 1986-02-26

Family

ID=24456492

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA852803A ZA852803B (en) 1984-05-23 1985-04-15 Purification of monoclonal antibodies

Country Status (11)

Country Link
US (1) US4604235A (ko)
EP (1) EP0162462B1 (ko)
JP (1) JPS60260593A (ko)
KR (1) KR870001434B1 (ko)
AT (1) ATE48615T1 (ko)
AU (1) AU576713B2 (ko)
CA (1) CA1218948A (ko)
DE (1) DE3574709D1 (ko)
IL (1) IL75006A (ko)
NZ (1) NZ211813A (ko)
ZA (1) ZA852803B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2571745B1 (fr) * 1984-10-17 1988-10-28 Trest Juzhvodoprovod Anticorrosif pour proteger la surface interne d'une canalisation contre la corrosion, procede d'obtention de cet anticorrosif et procede de protection de la surface interne d'une canalisation contre la corrosion utilisant cet anticorrosif
US4606825A (en) * 1985-04-22 1986-08-19 J. T. Baker Chemical Company Purification of immunoglobulin G
JPS6419024A (en) * 1987-07-15 1989-01-23 Tosoh Corp Separation of immunoglobulin g subclass
EP0367795A4 (en) * 1987-07-16 1992-01-15 E.I. Du Pont De Nemours And Company Affinity separating using immobilized flocculating reagents
US5157113A (en) * 1987-08-10 1992-10-20 Miles Inc. Removal of nucleic acids from monoclonal antibody preparations
EP0303088B1 (en) * 1987-08-10 1992-11-11 Miles Inc. Purified igm
IL90281A (en) * 1988-06-06 1994-10-07 Miles Inc Preparations containing MGI antibodies
DE3825429C2 (de) * 1988-07-27 1994-02-10 Biotest Pharma Gmbh Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt
US5126250A (en) * 1988-09-28 1992-06-30 Eli Lilly And Company Method for the reduction of heterogeneity of monoclonal antibodies
US5759864A (en) * 1995-06-23 1998-06-02 Cedars Sinai Medical Center Methods for reducing background binding in antibody preparations
JP4728140B2 (ja) * 2005-02-21 2011-07-20 国立大学法人九州大学 タンパク質の固定化方法
KR100795945B1 (ko) * 2005-08-24 2008-01-21 가부시키가이샤 엔.티.티.도코모 송신 전력 제어 방법 및 무선 네트워크 제어국
US8580935B2 (en) 2007-02-26 2013-11-12 Alltech Associates, Inc. Ultra-fast chromatography

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) * 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
CA1142466A (en) * 1979-01-09 1983-03-08 Cesar Milstein Cell lines
US4381295A (en) * 1979-04-26 1983-04-26 Ortho Pharmaceutical Corporation Monoclonal antibody to human helper T cells and methods of preparing same
US4271145A (en) * 1979-10-22 1981-06-02 The Massachusetts General Hospital Process for producing antibodies to hepatitis virus and cell lines therefor
US4361550A (en) * 1979-12-04 1982-11-30 Ortho Pharmaceutical Corporation Complement-fixing monoclonal antibody to human suppressor T cells and methods of preparing same
US4423147A (en) * 1980-04-11 1983-12-27 Secher David S Monoclonal antibody to interferon-α
US4427653A (en) * 1981-01-26 1984-01-24 President And Fellows Of Harvard College Method of making monoclonal antibodies
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
JPS5929622A (ja) * 1982-08-10 1984-02-16 Meiji Seika Kaisha Ltd モノクロ−ナル抗体、その製造法およびその用途
US4469630A (en) * 1983-11-25 1984-09-04 J. T. Baker Chemical Co. Purification of monoclonal antibodies

Also Published As

Publication number Publication date
IL75006A0 (en) 1985-08-30
DE3574709D1 (de) 1990-01-18
AU576713B2 (en) 1988-09-01
EP0162462A2 (en) 1985-11-27
KR870001434B1 (ko) 1987-08-06
EP0162462B1 (en) 1989-12-13
JPS60260593A (ja) 1985-12-23
EP0162462A3 (en) 1987-05-13
US4604235A (en) 1986-08-05
CA1218948A (en) 1987-03-10
NZ211813A (en) 1988-08-30
IL75006A (en) 1989-09-28
KR850008099A (ko) 1985-12-13
JPH0144315B2 (ko) 1989-09-27
ATE48615T1 (de) 1989-12-15
AU4144685A (en) 1985-11-28

Similar Documents

Publication Publication Date Title
EP0144028A3 (en) Purification of monoclonal antibodies
AU7256987A (en) Method of affinity purification employing monoclonal antibodies
EP0059754A4 (en) IMMUNOLOGICAL ANALYSIS USING HIGH AFFINITY MONOCLONIC IgM ANTIBODIES.
ZA852803B (en) Purification of monoclonal antibodies
GB2095831B (en) Monoclonal antibody reagent and method for immunological assay
DE3167698D1 (en) Method for the determination of antigens with the aid of two or more monoclonal antibodies
EP0249007A3 (en) A method of screening hybridomas
GB2114289B (en) Immunoassay for class specific immunoglobulin antibodies
ATE73674T1 (de) Reinigung des immunoglobulins g.
AU588542B2 (en) Immunoassay for breast cancer employing monoclonal antibodies
ES551494A0 (es) Procedimiento de obtencion de un anticuerpo monoclonal reactivos con antigenos de esporozoitos o merozoitos de eimeria spp.
AU579628B2 (en) Method of isolating monoclonal antibodies from hybridoma cultures
KR850006139A (ko) 방사성원소로 레이블된 단일클론항체의 제조방법
AU567681B2 (en) Immunoassay involving monoclonal igm antibody
GB8910263D0 (en) Monoclonal antibodies specific for an immunoglobulin isotype
AU5444386A (en) Anti-nicotine and anti-cotinine antibodies (monoclonal and polyclonal)
AU1550783A (en) Method of affinity purification employing monoclonal antibodies
DE3174878D1 (en) Immunoassay utilizing monoclonal high affinity igm antibodies
AU3375589A (en) Monoclonal antibodies specific for Hb A1c
CA1264148C (en) HYDROXYPALATITE FOR THE ANALYSIS AND PREPARATION OF PURIFIED MONOCLONAL ANTIBODIES
IL91034A0 (en) Monoclonal antibodies special for hb alc
IE850574L (en) Monoclonal antibody for pancreatic carcinoma