ZA845538B - Anthracyclin derivatives,a process for their preparation and their use as cytostatic agents - Google Patents

Anthracyclin derivatives,a process for their preparation and their use as cytostatic agents

Info

Publication number
ZA845538B
ZA845538B ZA845538A ZA845538A ZA845538B ZA 845538 B ZA845538 B ZA 845538B ZA 845538 A ZA845538 A ZA 845538A ZA 845538 A ZA845538 A ZA 845538A ZA 845538 B ZA845538 B ZA 845538B
Authority
ZA
South Africa
Prior art keywords
preparation
cytostatic agents
anthracyclin
derivatives
anthracyclin derivatives
Prior art date
Application number
ZA845538A
Other languages
English (en)
Inventor
Gerhard Huber
Hans Gerd Berscheid
Hans-Wolfram Fehlhaber
Hans Peter Kraemer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA845538B publication Critical patent/ZA845538B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA845538A 1983-07-19 1984-07-18 Anthracyclin derivatives,a process for their preparation and their use as cytostatic agents ZA845538B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833325957 DE3325957A1 (de) 1983-07-19 1983-07-19 Anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika

Publications (1)

Publication Number Publication Date
ZA845538B true ZA845538B (en) 1985-02-27

Family

ID=6204326

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA845538A ZA845538B (en) 1983-07-19 1984-07-18 Anthracyclin derivatives,a process for their preparation and their use as cytostatic agents

Country Status (20)

Country Link
US (1) US4737583A (sv)
EP (1) EP0131942B1 (sv)
JP (1) JPS6048994A (sv)
KR (1) KR850001226A (sv)
AR (1) AR240460A1 (sv)
AT (1) ATE30727T1 (sv)
AU (1) AU562684B2 (sv)
CA (1) CA1246062A (sv)
DE (2) DE3325957A1 (sv)
DK (1) DK352884A (sv)
ES (1) ES8600326A1 (sv)
FI (1) FI75173C (sv)
GR (1) GR81549B (sv)
HU (1) HU196422B (sv)
IL (1) IL72432A0 (sv)
NO (1) NO162023C (sv)
NZ (1) NZ208917A (sv)
PH (1) PH24156A (sv)
PT (1) PT78932A (sv)
ZA (1) ZA845538B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6117597A (ja) * 1984-07-03 1986-01-25 Microbial Chem Res Found アントラサイクリン化合物
DE3425357A1 (de) * 1984-07-10 1986-01-23 Hoechst Ag, 6230 Frankfurt 1-hydroxy-cytorhodine, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika
DE3524117A1 (de) * 1985-07-05 1987-02-05 Hoechst Ag Neue anthracyclin-tetrasaccharide, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatik
JPH0822869B2 (ja) * 1986-06-25 1996-03-06 ヘキストジヤパン株式会社 サイトロジンｓ誘導体およびそれを含有する抗癌剤
DE3641833A1 (de) * 1986-12-08 1988-06-09 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
DE3709337A1 (de) * 1987-03-21 1988-10-13 Hoechst Ag Neue anthracyclin-glycoside, ein verfahren zu ihrer herstellung und ihre verwendung als cytostatika
DE3733885A1 (de) * 1987-10-07 1989-04-27 Hoechst Ag Neue anthracyclin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3801178A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
DE3819092A1 (de) * 1988-06-04 1989-12-14 Behringwerke Ag Zytostatisch wirksame anthracyclinderivate
US20050208037A1 (en) * 2003-10-21 2005-09-22 Board Of Regents, The University Of Texas System Thioredoxin increases redox-cycling of anticancer agents thereby sensitizes cancer cells to apoptosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6023679B2 (ja) * 1979-07-13 1985-06-08 メルシャン株式会社 ロドマイシン群抗生物質とその製造法
JPS5982395A (ja) * 1982-11-02 1984-05-12 Microbial Chem Res Found アントラサイクリン化合物、その製造法およびその用途
JPS59148795A (ja) * 1983-02-08 1984-08-25 Microbial Chem Res Found アントラサイクリン化合物、その製造法およびその用途
DE3323025A1 (de) * 1983-06-25 1985-01-10 Hoechst Ag, 6230 Frankfurt Anthracyclin-derivate, ein mikrobiologisches verfahren zu ihrer herstellung und ihre verwendung als cytostatika

Also Published As

Publication number Publication date
PT78932A (de) 1984-08-01
FI75173C (sv) 1988-05-09
NO842938L (no) 1985-01-21
US4737583A (en) 1988-04-12
JPS6048994A (ja) 1985-03-16
HU196422B (en) 1988-11-28
AU3082384A (en) 1985-01-24
EP0131942B1 (de) 1987-11-11
ES534377A0 (es) 1985-10-01
NZ208917A (en) 1988-03-30
DE3467350D1 (en) 1987-12-17
HUT36837A (en) 1985-10-28
FI75173B (fi) 1988-01-29
DE3325957A1 (de) 1985-02-07
JPH0150714B2 (sv) 1989-10-31
ATE30727T1 (de) 1987-11-15
FI842877A0 (fi) 1984-07-17
NO162023B (no) 1989-07-17
AR240460A1 (es) 1990-04-30
CA1246062A (en) 1988-12-06
DK352884D0 (da) 1984-07-18
NO162023C (no) 1989-10-25
EP0131942A1 (de) 1985-01-23
ES8600326A1 (es) 1985-10-01
IL72432A0 (en) 1984-11-30
GR81549B (sv) 1984-12-11
AU562684B2 (en) 1987-06-18
KR850001226A (ko) 1985-03-16
FI842877A (fi) 1985-01-20
PH24156A (en) 1990-03-22
DK352884A (da) 1985-01-20

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