ZA845384B - Aqueous protein solutions which are stable towards denaturing,processes for their preparation and their use - Google Patents
Aqueous protein solutions which are stable towards denaturing,processes for their preparation and their useInfo
- Publication number
- ZA845384B ZA845384B ZA845384A ZA845384A ZA845384B ZA 845384 B ZA845384 B ZA 845384B ZA 845384 A ZA845384 A ZA 845384A ZA 845384 A ZA845384 A ZA 845384A ZA 845384 B ZA845384 B ZA 845384B
- Authority
- ZA
- South Africa
- Prior art keywords
- processes
- preparation
- formula
- protein solutions
- aqueous protein
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39591—Stabilisation, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833325223 DE3325223A1 (de) | 1983-07-13 | 1983-07-13 | Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA845384B true ZA845384B (en) | 1985-02-27 |
Family
ID=6203842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA845384A ZA845384B (en) | 1983-07-13 | 1984-07-12 | Aqueous protein solutions which are stable towards denaturing,processes for their preparation and their use |
Country Status (15)
Country | Link |
---|---|
US (1) | US4637834A (nl) |
EP (1) | EP0131864B1 (nl) |
JP (1) | JPS6038398A (nl) |
KR (1) | KR920002934B1 (nl) |
AT (1) | ATE56876T1 (nl) |
AU (1) | AU579106B2 (nl) |
DE (2) | DE3325223A1 (nl) |
DK (1) | DK168030B1 (nl) |
ES (2) | ES8600319A1 (nl) |
FI (1) | FI80276C (nl) |
GR (1) | GR81504B (nl) |
IE (1) | IE57694B1 (nl) |
IL (1) | IL72389A (nl) |
PT (1) | PT78892A (nl) |
ZA (1) | ZA845384B (nl) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3064888D1 (en) * | 1979-04-30 | 1983-10-27 | Hoechst Ag | Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization |
JPS61277633A (ja) * | 1985-05-31 | 1986-12-08 | Toray Ind Inc | インタ−フエロン組成物 |
US5183746A (en) * | 1986-10-27 | 1993-02-02 | Schering Aktiengesellschaft | Formulation processes for pharmaceutical compositions of recombinant β- |
US4956274A (en) * | 1987-04-06 | 1990-09-11 | Microgenics Corporation | Reagent stabilization in enzyme-donor and acceptor assay |
US5004605A (en) * | 1987-12-10 | 1991-04-02 | Cetus Corporation | Low pH pharmaceutical compositions of recombinant β-interferon |
US5763394A (en) * | 1988-04-15 | 1998-06-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
US5981485A (en) * | 1997-07-14 | 1999-11-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
US5078997A (en) * | 1988-07-13 | 1992-01-07 | Cetus Corporation | Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers |
US5945098A (en) * | 1990-02-01 | 1999-08-31 | Baxter International Inc. | Stable intravenously-administrable immune globulin preparation |
US5830452A (en) * | 1990-11-20 | 1998-11-03 | Chiron Corporation | Method for enhancing the anti-tumor therapeutic index of interleukin-2 |
JPH08502021A (ja) * | 1992-04-07 | 1996-03-05 | マリンクロッド・ヴェタラネリィ・インコーポレイテッド | 生体相容性ソマトトロピン溶液 |
DK0955062T3 (da) * | 1992-07-31 | 2007-09-17 | Genentech Inc | Vandig formulering indeholdende humant væksthormon |
US6790439B1 (en) | 1995-06-07 | 2004-09-14 | Zymogenetics, Inc. | Thrombopoietin compositions |
PT1602667E (pt) * | 1995-06-07 | 2007-07-13 | Searle Llc | Formulação aquosa que compreende tfpi e agentes de solubilização |
MX9602398A (es) * | 1995-06-23 | 1997-02-28 | Kimberly Clark Co | Material polimerico modificado teniendo humectabilidad mejorada. |
AUPN801296A0 (en) * | 1996-02-12 | 1996-03-07 | Csl Limited | Stabilised growth hormone formulation and method of preparation thereof |
BR0013162A (pt) * | 1999-07-12 | 2002-05-28 | Grandis Biotech Gmbh | Formulações de hormÈnio de crescimento |
CN1668332A (zh) * | 2002-07-09 | 2005-09-14 | 桑多斯股份公司 | 包含苯酚的含高浓度人生长激素的液体制剂 |
EP1654283B1 (en) * | 2003-08-13 | 2011-07-13 | Novartis Vaccines and Diagnostics, Inc. | Improved method of purifying tfpi and tfpi analogs |
AU2005237775B2 (en) | 2004-04-07 | 2010-03-04 | Ares Trading S.A. | Liquid growth hormone formulation |
EP1847830A1 (en) * | 2006-04-20 | 2007-10-24 | TF Instruments, Inc. | Determining optimal concentrations of protective additives for biomolecules |
WO2024133849A1 (en) * | 2022-12-22 | 2024-06-27 | The Protein Brewery B.V. | Ovalbumin fermentation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4439355A (en) * | 1976-12-02 | 1984-03-27 | Colgate-Palmolive Company | Elastic detergent product of improved foaming power after use |
DE3064888D1 (en) * | 1979-04-30 | 1983-10-27 | Hoechst Ag | Aqueous solutions of proteins stable against denaturization, process for their manufacture, and their utilization |
DE2917535C2 (de) * | 1979-04-30 | 1986-10-30 | Hoechst Ag, 6230 Frankfurt | Gegen Denaturierung beständige Insulinlösungen |
JPS58501125A (ja) * | 1981-07-17 | 1983-07-14 | ノルデイスク・インスリンラボラトリウム | 安定な水性治療性インシユリン製剤及びその製造方法 |
-
1983
- 1983-07-13 DE DE19833325223 patent/DE3325223A1/de not_active Withdrawn
-
1984
- 1984-07-06 DE DE8484107889T patent/DE3483287D1/de not_active Expired - Lifetime
- 1984-07-06 EP EP84107889A patent/EP0131864B1/de not_active Expired - Lifetime
- 1984-07-06 AT AT84107889T patent/ATE56876T1/de not_active IP Right Cessation
- 1984-07-11 FI FI842798A patent/FI80276C/fi not_active IP Right Cessation
- 1984-07-11 GR GR75278A patent/GR81504B/el unknown
- 1984-07-11 ES ES534195A patent/ES8600319A1/es not_active Expired
- 1984-07-12 DK DK342684A patent/DK168030B1/da not_active IP Right Cessation
- 1984-07-12 IE IE1796/84A patent/IE57694B1/en not_active IP Right Cessation
- 1984-07-12 JP JP59143378A patent/JPS6038398A/ja active Granted
- 1984-07-12 ZA ZA845384A patent/ZA845384B/xx unknown
- 1984-07-12 KR KR1019840004074A patent/KR920002934B1/ko not_active IP Right Cessation
- 1984-07-12 PT PT78892A patent/PT78892A/pt active IP Right Revival
- 1984-07-12 IL IL72389A patent/IL72389A/xx not_active IP Right Cessation
- 1984-07-12 AU AU30537/84A patent/AU579106B2/en not_active Expired
- 1984-08-29 ES ES535482A patent/ES8609361A1/es not_active Expired
-
1986
- 1986-02-05 US US06/825,965 patent/US4637834A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3483287D1 (de) | 1990-10-31 |
ES534195A0 (es) | 1985-10-01 |
DE3325223A1 (de) | 1985-01-24 |
AU579106B2 (en) | 1988-11-17 |
FI842798A (fi) | 1985-01-14 |
FI842798A0 (fi) | 1984-07-11 |
IE841796L (en) | 1985-01-13 |
JPH0582397B2 (nl) | 1993-11-18 |
ES8609361A1 (es) | 1986-09-01 |
AU3053784A (en) | 1985-01-17 |
EP0131864A2 (de) | 1985-01-23 |
US4637834A (en) | 1987-01-20 |
FI80276B (fi) | 1990-01-31 |
KR850000971A (ko) | 1985-03-14 |
FI80276C (fi) | 1990-05-10 |
KR920002934B1 (ko) | 1992-04-10 |
JPS6038398A (ja) | 1985-02-27 |
DK342684D0 (da) | 1984-07-12 |
IE57694B1 (en) | 1993-03-10 |
DK168030B1 (da) | 1994-01-24 |
DK342684A (da) | 1985-01-14 |
ATE56876T1 (de) | 1990-10-15 |
EP0131864B1 (de) | 1990-09-26 |
EP0131864A3 (en) | 1987-08-26 |
PT78892A (de) | 1984-08-01 |
GR81504B (nl) | 1984-12-11 |
IL72389A0 (en) | 1984-11-30 |
ES8600319A1 (es) | 1985-10-01 |
ES535482A0 (es) | 1986-09-01 |
IL72389A (en) | 1988-11-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL72389A0 (en) | Aqueous protein solutions which are stable towards denaturing,processes for their preparation and their use | |
NZ220546A (en) | Benzothiophene- and benzofuran- amides and compositions | |
EP0886648A4 (en) | COMPOUNDS AND PEPTIDES BINDING THE ERYTHROPOIETIN RECEPTOR | |
GR3002618T3 (en) | Solutions of oxazaphosphorins with enhanced stability and process for their preparation | |
EP0373549A3 (de) | Enzym-hemmende Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und ihre Verwendung | |
ES2045485T3 (es) | Metodo de preparacion de derivados de fenil-6 piperazinilalquil-3 1h, 3h-pirimidinediona-2,4, y su aplicacion en terapeutica. | |
AU555418B2 (en) | Muramyl peptides | |
AU1779188A (en) | Guanidine-related compounds comprising a substituted tetraphenylborate ion, process for obtaining these compounds, and use of the compounds | |
PT90814A (pt) | Processo de preparacao de derivados da fenotiazina | |
DE3664634D1 (en) | Substituted o-sulfonyl-glycosyl amides, method for their preparation and their use as mediacments | |
DE59007216D1 (de) | Verfahren zur Herstellung von Clausenamid und Neoclausenamid und deren Derivate. | |
ES2043784T3 (es) | Procedimiento de preparacion de compuestos guanidinicos. | |
ATE111087T1 (de) | Verfahren zur herstellung von 2-aryl-2h-1,2,3- triazolen. | |
IT1240323B (it) | Processo per indurre la secrezione di proteine da cellule eucariote |