ZA839347B - New 2-azabicyclo(2.2.1)heptane derivatives,processes for their preparation,agents containing these compounds and their use,and 2-azabicyclo(2.2.1)heptane derivatives as intermediates and processes for their preparation - Google Patents

New 2-azabicyclo(2.2.1)heptane derivatives,processes for their preparation,agents containing these compounds and their use,and 2-azabicyclo(2.2.1)heptane derivatives as intermediates and processes for their preparation

Info

Publication number
ZA839347B
ZA839347B ZA839347A ZA839347A ZA839347B ZA 839347 B ZA839347 B ZA 839347B ZA 839347 A ZA839347 A ZA 839347A ZA 839347 A ZA839347 A ZA 839347A ZA 839347 B ZA839347 B ZA 839347B
Authority
ZA
South Africa
Prior art keywords
azabicyclo
processes
preparation
heptane derivatives
intermediates
Prior art date
Application number
ZA839347A
Other languages
English (en)
Inventor
Rainer Henning
Hansjoerg Urbach
Reinhard Becker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA839347B publication Critical patent/ZA839347B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA839347A 1982-12-17 1983-12-15 New 2-azabicyclo(2.2.1)heptane derivatives,processes for their preparation,agents containing these compounds and their use,and 2-azabicyclo(2.2.1)heptane derivatives as intermediates and processes for their preparation ZA839347B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823246757 DE3246757A1 (de) 1982-12-17 1982-12-17 Neue 2-azabicyclo(2.2.1)heptan-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(2.2.1)heptan-derivate als zwischenprodukte und verfahren zu deren herstellung

Publications (1)

Publication Number Publication Date
ZA839347B true ZA839347B (en) 1984-08-29

Family

ID=6180952

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA839347A ZA839347B (en) 1982-12-17 1983-12-15 New 2-azabicyclo(2.2.1)heptane derivatives,processes for their preparation,agents containing these compounds and their use,and 2-azabicyclo(2.2.1)heptane derivatives as intermediates and processes for their preparation

Country Status (10)

Country Link
EP (1) EP0113880A3 (enrdf_load_html_response)
JP (1) JPS59130268A (enrdf_load_html_response)
KR (1) KR840006971A (enrdf_load_html_response)
AU (1) AU2249583A (enrdf_load_html_response)
DE (1) DE3246757A1 (enrdf_load_html_response)
DK (1) DK581183A (enrdf_load_html_response)
ES (2) ES528066A0 (enrdf_load_html_response)
GR (1) GR79480B (enrdf_load_html_response)
PT (1) PT77825B (enrdf_load_html_response)
ZA (1) ZA839347B (enrdf_load_html_response)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303344A1 (de) 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten aminosaeuren und deren estern
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3839127A1 (de) * 1988-11-19 1990-05-23 Hoechst Ag Pyrrolidon-2-carbonsaeure-derivate mit psychotroper wirkung
DD284030A5 (de) 1988-11-24 1990-10-31 Hoechst Ag,De Verfahren zur herstellung von peptiden mit bradykinin-antagonistischer wirkung
FR2655989B1 (fr) * 1989-12-20 1992-02-28 Adir Nouveaux derives d'amino-acides substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US6121280A (en) * 1998-03-24 2000-09-19 Pfizer Inc. Azabicyclic rotomase inhibitors
RU2712097C1 (ru) * 2018-09-28 2020-01-24 Общество с ограниченной ответственностью "Необиотек" Ингибитор дипептидилпептидазы-4 для лечения сахарного диабета 2-го типа, соединения (варианты)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2492381A1 (fr) * 1980-10-21 1982-04-23 Science Union & Cie Nouveaux acides aza bicyclo alcane carboxyliques substitues leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme

Also Published As

Publication number Publication date
ES8500946A1 (es) 1984-11-01
PT77825A (de) 1984-01-01
ES8501401A1 (es) 1984-11-16
EP0113880A2 (de) 1984-07-25
ES530388A0 (es) 1984-11-01
EP0113880A3 (en) 1984-09-26
GR79480B (enrdf_load_html_response) 1984-10-30
AU2249583A (en) 1984-06-21
DK581183A (da) 1984-06-18
DE3246757A1 (de) 1984-06-20
JPS59130268A (ja) 1984-07-26
PT77825B (de) 1986-05-27
ES528066A0 (es) 1984-11-16
DK581183D0 (da) 1983-12-16
KR840006971A (ko) 1984-12-07

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