ZA83733B - Benzothienylalkylamines,processes for the production and their use as pharmaceuticals - Google Patents

Benzothienylalkylamines,processes for the production and their use as pharmaceuticals

Info

Publication number
ZA83733B
ZA83733B ZA83733A ZA83733A ZA83733B ZA 83733 B ZA83733 B ZA 83733B ZA 83733 A ZA83733 A ZA 83733A ZA 83733 A ZA83733 A ZA 83733A ZA 83733 B ZA83733 B ZA 83733B
Authority
ZA
South Africa
Prior art keywords
benzothienylalkylamines
pharmaceuticals
processes
production
Prior art date
Application number
ZA83733A
Other languages
English (en)
Inventor
Anton Stutz
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA83733B publication Critical patent/ZA83733B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/56Radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heat-Exchange Devices With Radiators And Conduit Assemblies (AREA)
  • Refuge Islands, Traffic Blockers, Or Guard Fence (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
ZA83733A 1982-02-03 1983-02-03 Benzothienylalkylamines,processes for the production and their use as pharmaceuticals ZA83733B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH656/82A CH653028A5 (de) 1982-02-03 1982-02-03 Benzthiophenallylamin-verbindungen und verfahren zu ihrer herstellung.

Publications (1)

Publication Number Publication Date
ZA83733B true ZA83733B (en) 1984-09-26

Family

ID=4192086

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA83733A ZA83733B (en) 1982-02-03 1983-02-03 Benzothienylalkylamines,processes for the production and their use as pharmaceuticals

Country Status (28)

Country Link
US (2) US4474141A (es)
JP (1) JPS58146580A (es)
AT (1) AT391865B (es)
AU (1) AU569838B2 (es)
BE (1) BE895751A (es)
CA (1) CA1193271A (es)
CH (1) CH653028A5 (es)
CY (1) CY1485A (es)
DE (1) DE3302814A1 (es)
DK (1) DK160043C (es)
ES (1) ES519477A0 (es)
FI (1) FI80689C (es)
FR (1) FR2520741B1 (es)
GB (1) GB2116171B (es)
HK (1) HK47789A (es)
HU (1) HU190886B (es)
IE (1) IE55073B1 (es)
IL (1) IL67813A0 (es)
IT (1) IT1197565B (es)
KE (1) KE3877A (es)
MY (1) MY8700167A (es)
NL (1) NL8300350A (es)
NZ (1) NZ203144A (es)
PH (1) PH22625A (es)
PT (1) PT76175B (es)
SE (1) SE455095B (es)
SG (1) SG16289G (es)
ZA (1) ZA83733B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH672311A5 (es) * 1985-09-14 1989-11-15 Sandoz Ag
US5068359A (en) * 1989-06-20 1991-11-26 Ciba-Geigy Corporation Microbicidal compositions
AU634871B2 (en) * 1990-03-20 1993-03-04 Banyu Pharmaceutical Co., Ltd. Substituted amine derivatives having anti-hyperlipemia activity
FR2695930B1 (fr) * 1992-09-22 1994-12-23 Sanofi Elf Dérivé du 2-éthyl benzo[b]thiophène, son procédé de préparation et son utilisation comme intermédiaire de synthèse.
JP4759500B2 (ja) * 2001-02-22 2011-08-31 帝人株式会社 ベンゾ[b]チオフェン誘導体、およびその製造方法
TW200734321A (en) * 2005-10-27 2007-09-16 Teijin Pharma Ltd Benzo [b] thiophen derivatives and a process for producing benzo [b] thiophen derivatives
CN102898314B (zh) * 2012-11-13 2014-09-03 山东铂源药业有限公司 一种盐酸特比萘芬的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1250019B (es) * 1963-07-19
CH442353A (de) * 1964-04-16 1967-08-31 Sandoz Ag Verfahren zur Herstellung von neuen Benzothiophen-Derivaten
US3930537A (en) * 1974-05-06 1976-01-06 The United States Of America As Represented By The United States Energy Research And Development Administration Heat exchanger
DE2862103D1 (en) * 1977-08-19 1982-11-18 Sandoz Ag Propenyl amines, processes for their production and pharmaceutical compositions containing them
DE19975055I1 (de) * 1979-08-22 2000-01-27 Novartis Ag Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwending als Arzneimittel

Also Published As

Publication number Publication date
HK47789A (en) 1989-06-23
IE830202L (en) 1983-08-03
PH22625A (en) 1988-10-28
IE55073B1 (en) 1990-05-23
JPH0446275B2 (es) 1992-07-29
FI830297L (fi) 1983-08-04
AU1089783A (en) 1983-08-11
ES8403473A1 (es) 1984-03-16
DE3302814A1 (de) 1983-08-11
CA1193271A (en) 1985-09-10
ES519477A0 (es) 1984-03-16
JPS58146580A (ja) 1983-09-01
CH653028A5 (de) 1985-12-13
US4474141A (en) 1984-10-02
FI80689C (fi) 1990-07-10
AU569838B2 (en) 1988-02-25
GB2116171B (en) 1986-04-03
PT76175B (en) 1986-01-15
KE3877A (en) 1989-07-21
IT8347666A0 (it) 1983-02-03
DE3302814C2 (es) 1992-06-25
BE895751A (fr) 1983-08-01
DK40883D0 (da) 1983-02-01
IL67813A0 (en) 1983-06-15
DK160043B (da) 1991-01-21
SG16289G (en) 1989-07-07
FR2520741B1 (fr) 1986-03-21
CY1485A (en) 1989-12-08
GB8302573D0 (en) 1983-03-02
HU190886B (en) 1986-12-28
SE8300535L (sv) 1983-08-04
US4737516A (en) 1988-04-12
DK160043C (da) 1991-06-17
AT391865B (de) 1990-12-10
NL8300350A (nl) 1983-09-01
FR2520741A1 (fr) 1983-08-05
MY8700167A (en) 1987-12-31
NZ203144A (en) 1985-12-13
SE455095B (sv) 1988-06-20
DK40883A (da) 1983-08-04
IT1197565B (it) 1988-12-06
ATA34983A (de) 1990-06-15
GB2116171A (en) 1983-09-21
FI830297A0 (fi) 1983-01-27
FI80689B (fi) 1990-03-30
PT76175A (en) 1983-03-01
SE8300535D0 (sv) 1983-02-01

Similar Documents

Publication Publication Date Title
DE3372211D1 (en) Agarose-polyaldehyde beads, process for their production and their use
DE3474446D1 (en) Substituted 1-amino-4-nitro-acridinones, pharmaceutical compositions comprising the same and processes for their production
IL73159A (en) Carboxyalkenamido-cephalosporins,processes for the preparation thereof and methods for the use thereof
DE3377795D1 (en) Spergualin-related compounds, processes for the preparation thereof and their use as medicaments
DE3176313D1 (en) Novel halogenated prostacyclins, process for the production thereof, and pharmaceutical use thereof
ZA836072B (en) Desoxyuridine derivatives,processes for their preparation and their use as pharmaceuticals
IL67808A (en) Plant-promoting preparations,process for manufacture thereof and methods for the use thereof
ZA898101B (en) Bromonitro compound,process for the production thereof and use as blocide
DE3371199D1 (en) Novel 6-nitroprostaglandin derivatives, process for production thereof, and use thereof
DE3273986D1 (en) Homobrassinolide, and its production and use
ZA83733B (en) Benzothienylalkylamines,processes for the production and their use as pharmaceuticals
DE3361924D1 (en) Polypeptide-diesters, their production and use
DE3268290D1 (en) Addition compounds, process for their production and their use
DE3260505D1 (en) Alicyclic compounds, their production and use
ZA781242B (en) Benzylpyrimidines,process for their production,and pharmaceuticals containing the same
DE3163199D1 (en) Novel pentapeptides, processes for their production, pharmaceutical compositions comprising said pentapeptides and their use
IL67852A (en) Chloracetamides,their production and their use as herbicides
ZA832742B (en) 1-sulfo-2-azetidinone derivatives,their production and use
ZA834598B (en) Dithiolane derivative,process for producing the same and use thereof
ZA847781B (en) Fluoralkylated carbapeneme derivatives,processes for the production and their use
ZA821491B (en) Novel n-acyl-polypeptides and processes for the production thereof
IL66759A (en) A-32724 antibiotics,process for production thereof and the use thereof
OA07352A (en) N-substitued-tetrahydrothiazines, process for their preparation, and their use as pesticides.
DE3267439D1 (en) Trifluoromethanesulfonanilides, and their production and use
DE3070729D1 (en) Des-a-steroids, their production and some des-a-steroids for use as medicines