ZA827132B - Pyrazinium substituted cephalosporin - Google Patents

Pyrazinium substituted cephalosporin

Info

Publication number
ZA827132B
ZA827132B ZA827132A ZA827132A ZA827132B ZA 827132 B ZA827132 B ZA 827132B ZA 827132 A ZA827132 A ZA 827132A ZA 827132 A ZA827132 A ZA 827132A ZA 827132 B ZA827132 B ZA 827132B
Authority
ZA
South Africa
Prior art keywords
pyrazinium
substituted cephalosporin
cephalosporin
substituted
pyrazinium substituted
Prior art date
Application number
ZA827132A
Other languages
English (en)
Inventor
Henry Walker Lunn William
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA827132B publication Critical patent/ZA827132B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA827132A 1981-10-02 1982-09-29 Pyrazinium substituted cephalosporin ZA827132B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/307,984 US4401668A (en) 1981-10-02 1981-10-02 Pyrazinium substituted cephalosporins

Publications (1)

Publication Number Publication Date
ZA827132B true ZA827132B (en) 1984-05-30

Family

ID=23192027

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA827132A ZA827132B (en) 1981-10-02 1982-09-29 Pyrazinium substituted cephalosporin

Country Status (14)

Country Link
US (1) US4401668A (xx)
JP (1) JPS5872591A (xx)
AU (1) AU549818B2 (xx)
BE (1) BE894562A (xx)
DE (1) DE3236066A1 (xx)
FR (1) FR2514005B1 (xx)
GB (1) GB2106906B (xx)
IE (1) IE54050B1 (xx)
IL (1) IL66887A (xx)
IT (1) IT1163014B (xx)
NL (1) NL8203806A (xx)
NZ (1) NZ202033A (xx)
PH (1) PH19830A (xx)
ZA (1) ZA827132B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
DK330880A (da) * 1979-08-03 1981-02-04 Beecham Group Ltd Fremgangsmaade til fremstilling af clavulansyrederivater
EP0053893B1 (en) * 1980-12-09 1985-03-20 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
US4562182A (en) * 1980-12-23 1985-12-31 Beecham Group P.L.C. Compounds containing beta-lactams
ES8306160A1 (es) * 1981-04-03 1983-05-01 Fujisawa Pharmaceutical Co "procedimiento para preparar un nuevo compuesto de cefem".
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
ATE121746T1 (de) * 1984-11-23 1995-05-15 Biochemie Gmbh Verfahren zur herstellung bissilylierter 3- iodmethylcephalosporinderivaten.
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
CN86107947A (zh) * 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
EP0304858A3 (en) * 1987-08-25 1989-12-20 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
IE63094B1 (en) * 1987-09-14 1995-03-22 Fujisawa Pharmaceutical Co Cephem compound and a process for preparation thereof
KR0157073B1 (ko) * 1992-10-01 1998-11-16 김태훈 세팔로스포린 유도체 및 그의 제조방법
EP1666483B1 (en) * 2003-09-09 2011-08-17 Nippon Chemical Industrial Company Limited Process for producing 3-chloromethyl-3-cephem derivative

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024133A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(thienyl-,furyl- or pyridylacetamido)]cephalosporins
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
FR2449692A1 (fr) 1979-02-23 1980-09-19 Glaxo Group Ltd Nouvelles cephalosporines qui exercent une activite contre les organismes gram-negatifs

Also Published As

Publication number Publication date
AU8891982A (en) 1983-04-14
US4401668A (en) 1983-08-30
DE3236066A1 (de) 1983-04-14
PH19830A (en) 1986-07-16
IE54050B1 (en) 1989-05-24
JPS5872591A (ja) 1983-04-30
IE822371L (en) 1983-04-02
NL8203806A (nl) 1983-05-02
NZ202033A (en) 1985-09-13
IT8223567A0 (it) 1982-09-30
IL66887A0 (en) 1982-12-31
IT1163014B (it) 1987-04-08
IL66887A (en) 1985-09-29
FR2514005A1 (fr) 1983-04-08
GB2106906A (en) 1983-04-20
BE894562A (fr) 1983-03-30
AU549818B2 (en) 1986-02-13
GB2106906B (en) 1985-09-18
FR2514005B1 (fr) 1986-03-14

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