IT1163014B - Cefalosporine pirazinio sostituite e relativa formulazione - Google Patents

Cefalosporine pirazinio sostituite e relativa formulazione

Info

Publication number
IT1163014B
IT1163014B IT23567/82A IT2356782A IT1163014B IT 1163014 B IT1163014 B IT 1163014B IT 23567/82 A IT23567/82 A IT 23567/82A IT 2356782 A IT2356782 A IT 2356782A IT 1163014 B IT1163014 B IT 1163014B
Authority
IT
Italy
Prior art keywords
pyrazinum
cephalosporine
replaced
related formulation
formulation
Prior art date
Application number
IT23567/82A
Other languages
English (en)
Other versions
IT8223567A0 (it
Inventor
William Henry Walker Lunn
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IT8223567A0 publication Critical patent/IT8223567A0/it
Application granted granted Critical
Publication of IT1163014B publication Critical patent/IT1163014B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT23567/82A 1981-10-02 1982-09-30 Cefalosporine pirazinio sostituite e relativa formulazione IT1163014B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/307,984 US4401668A (en) 1981-10-02 1981-10-02 Pyrazinium substituted cephalosporins

Publications (2)

Publication Number Publication Date
IT8223567A0 IT8223567A0 (it) 1982-09-30
IT1163014B true IT1163014B (it) 1987-04-08

Family

ID=23192027

Family Applications (1)

Application Number Title Priority Date Filing Date
IT23567/82A IT1163014B (it) 1981-10-02 1982-09-30 Cefalosporine pirazinio sostituite e relativa formulazione

Country Status (14)

Country Link
US (1) US4401668A (it)
JP (1) JPS5872591A (it)
AU (1) AU549818B2 (it)
BE (1) BE894562A (it)
DE (1) DE3236066A1 (it)
FR (1) FR2514005B1 (it)
GB (1) GB2106906B (it)
IE (1) IE54050B1 (it)
IL (1) IL66887A (it)
IT (1) IT1163014B (it)
NL (1) NL8203806A (it)
NZ (1) NZ202033A (it)
PH (1) PH19830A (it)
ZA (1) ZA827132B (it)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1582884A (en) * 1977-05-19 1981-01-14 Beecham Group Ltd Clavulanic acid derivatives their preparation and use
DK330880A (da) * 1979-08-03 1981-02-04 Beecham Group Ltd Fremgangsmaade til fremstilling af clavulansyrederivater
EP0053893B1 (en) * 1980-12-09 1985-03-20 Beecham Group Plc Derivatives of clavulanic acid, their preparation and their use
NZ199200A (en) * 1980-12-23 1984-07-31 Beecham Group Ltd Clavulanic acid derivatives and pharmaceutical compositions
DE3279470D1 (en) * 1981-04-03 1989-04-06 Fujisawa Pharmaceutical Co New cephem compounds, processes for their preparation, pharmaceutical compositions containing them and their starting compounds
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
DE3336757A1 (de) * 1983-10-08 1985-04-25 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
ATE121746T1 (de) * 1984-11-23 1995-05-15 Biochemie Gmbh Verfahren zur herstellung bissilylierter 3- iodmethylcephalosporinderivaten.
US4703118A (en) * 1985-04-08 1987-10-27 Eli Lilly And Company Synthesis of 3-iodomethyl cephalosporins
CN86107947A (zh) * 1985-11-22 1987-05-27 藤沢药品工业株式会社 新的头孢烯化合物及其制备方法
EP0304858A3 (en) * 1987-08-25 1989-12-20 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
IE63094B1 (en) * 1987-09-14 1995-03-22 Fujisawa Pharmaceutical Co Cephem compound and a process for preparation thereof
KR0157073B1 (ko) * 1992-10-01 1998-11-16 김태훈 세팔로스포린 유도체 및 그의 제조방법
EP1666483B1 (en) * 2003-09-09 2011-08-17 Nippon Chemical Industrial Company Limited Process for producing 3-chloromethyl-3-cephem derivative

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024133A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(thienyl-,furyl- or pyridylacetamido)]cephalosporins
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GR63088B (en) * 1976-04-14 1979-08-09 Takeda Chemical Industries Ltd Preparation process of novel cephalosporins
JPS609719B2 (ja) * 1977-08-06 1985-03-12 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
AU536966B2 (en) 1979-02-23 1984-05-31 Glaxo Group Limited Cephalosporin antibiotics

Also Published As

Publication number Publication date
IT8223567A0 (it) 1982-09-30
FR2514005A1 (fr) 1983-04-08
DE3236066A1 (de) 1983-04-14
GB2106906B (en) 1985-09-18
GB2106906A (en) 1983-04-20
FR2514005B1 (fr) 1986-03-14
IL66887A0 (en) 1982-12-31
IE54050B1 (en) 1989-05-24
JPS5872591A (ja) 1983-04-30
NL8203806A (nl) 1983-05-02
BE894562A (fr) 1983-03-30
ZA827132B (en) 1984-05-30
AU549818B2 (en) 1986-02-13
AU8891982A (en) 1983-04-14
US4401668A (en) 1983-08-30
IE822371L (en) 1983-04-02
NZ202033A (en) 1985-09-13
IL66887A (en) 1985-09-29
PH19830A (en) 1986-07-16

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