ZA81964B - Method of production of immunoglobulin having high content of monomer - Google Patents

Method of production of immunoglobulin having high content of monomer

Info

Publication number
ZA81964B
ZA81964B ZA00810964A ZA81964A ZA81964B ZA 81964 B ZA81964 B ZA 81964B ZA 00810964 A ZA00810964 A ZA 00810964A ZA 81964 A ZA81964 A ZA 81964A ZA 81964 B ZA81964 B ZA 81964B
Authority
ZA
South Africa
Prior art keywords
immunoglobulin
monomer
high content
production
fractionation
Prior art date
Application number
ZA00810964A
Other languages
English (en)
Inventor
Tsunemasa Yoshida
Yoshida Tsunemasa
Akinobu Funatsu
Funatsu Akinobu
Komei Ohashi
Ohashi Komei
Tetsuro Sato
Sato Tetsuro
Shoji Ono
Ono Shoji
Original Assignee
Chemo Sero Therapeut Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemo Sero Therapeut Res Inst filed Critical Chemo Sero Therapeut Res Inst
Publication of ZA81964B publication Critical patent/ZA81964B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA00810964A 1980-02-14 1981-02-13 Method of production of immunoglobulin having high content of monomer ZA81964B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1737080A JPS56113713A (en) 1980-02-14 1980-02-14 Preparation of immunoglobulin with high content of monomer

Publications (1)

Publication Number Publication Date
ZA81964B true ZA81964B (en) 1982-03-31

Family

ID=11942133

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00810964A ZA81964B (en) 1980-02-14 1981-02-13 Method of production of immunoglobulin having high content of monomer

Country Status (7)

Country Link
US (1) US4384993A (fr)
EP (1) EP0035616B1 (fr)
JP (1) JPS56113713A (fr)
AT (1) ATE9905T1 (fr)
CA (1) CA1137413A (fr)
DE (1) DE3069460D1 (fr)
ZA (1) ZA81964B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362661A (en) * 1979-08-09 1982-12-07 Teijin Limited Immunoglobulin composition having a high monomer content, and process for production thereof
EP0116571B2 (fr) * 1982-08-30 1997-10-29 BAXTER INTERNATIONAL INC. (a Delaware corporation) Procede de fabrication de compositions contenant de la gamma globuline
US4634417A (en) * 1982-12-06 1987-01-06 Georgetown University Process for treatment of tumors and apparatus therefor
DK166763B1 (da) * 1983-03-16 1993-07-12 Immuno Ag Immunoglobulin-g-holdig fraktion
US4732863A (en) * 1984-12-31 1988-03-22 University Of New Mexico PEG-modified antibody with reduced affinity for cell surface Fc receptors
US4597966A (en) * 1985-01-09 1986-07-01 Ortho Diagnostic Systems, Inc. Histidine stabilized immunoglobulin and method of preparation
JPH0662436B2 (ja) * 1986-05-19 1994-08-17 株式会社ミドリ十字 静注用免疫グロブリン製剤の製造方法
AU4803890A (en) * 1988-12-15 1990-07-10 Invitron Corporation Use of basic amino acids to solubilize immunoglobulins
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
US5219578A (en) * 1991-02-25 1993-06-15 Innovet, Inc. Composition and method for immunostimulation in mammals
US5514781A (en) * 1994-04-11 1996-05-07 Bayer Corporation Use of azoles as virucidal agents in solutions of biologically active proteins
EP0852951A1 (fr) * 1996-11-19 1998-07-15 Roche Diagnostics GmbH Compositions pharmaceutiques stables, lyophilisées d'anticorps monoclonaux ou polyclonaux
US6187309B1 (en) * 1999-09-14 2001-02-13 Milkaus Laboratory, Inc. Method for treatment of symptoms of central nervous system disorders
US6294171B2 (en) * 1999-09-14 2001-09-25 Milkhaus Laboratory, Inc. Methods for treating disease states comprising administration of low levels of antibodies
US6436401B1 (en) 1999-09-14 2002-08-20 Milkhaus Laboratory, Inc. Methods for alleviating symptoms associated with diabetes and diabetic neuropathy comprising administration of low levels of antibodies
US6713058B2 (en) 1999-09-14 2004-03-30 Milkhaus Laboratory, Inc. Methods for alleviating symptoms associated with neuropathic conditions comprising administration of low levels of antibodies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382227A (en) * 1967-01-30 1968-05-07 Pentex Inc Blood protein fractionation employing 2-ethoxy-6, 9-diamino-acridine-lactate
DE2001902C3 (de) * 1970-01-16 1978-10-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Reinigung und Fraktionierung von gelösten aktiven Proteinen
DE2508132C3 (de) * 1974-03-08 1980-10-16 Teijin Ltd., Osaka (Japan) Verfahren zur Herstellung von Humanimmunglobulin-Derivaten und parenteral applizierbare Lösung hiervon
US4118379A (en) * 1974-09-06 1978-10-03 Behringwerke Aktiengesellschaft Amidated immune globulins and process for preparing them
JPS5625115A (en) * 1979-08-09 1981-03-10 Teijin Ltd Immunoglobulin composition
JPS5625116A (en) * 1979-08-09 1981-03-10 Teijin Ltd Preparation of immunoglobulin having high content of monomer
US4362661A (en) * 1979-08-09 1982-12-07 Teijin Limited Immunoglobulin composition having a high monomer content, and process for production thereof
US4374763A (en) * 1979-09-17 1983-02-22 Morishita Pharmaceutical Co., Ltd. Method for producing gamma-globulin for use in intravenous administration and method for producing a pharmaceutical preparation thereof

Also Published As

Publication number Publication date
CA1137413A (fr) 1982-12-14
EP0035616B1 (fr) 1984-10-17
DE3069460D1 (en) 1984-11-22
ATE9905T1 (de) 1984-11-15
US4384993A (en) 1983-05-24
EP0035616A1 (fr) 1981-09-16
JPS56113713A (en) 1981-09-07
JPS6160817B2 (fr) 1986-12-23

Similar Documents

Publication Publication Date Title
DE3069460D1 (en) Production of immunoglobulin having a high monomer content
AU3110989A (en) Homogeneous succinimide/benzotriazole compositions and their formation
KR830009777A (ko) 흑색종 치료에 유용한 물질의 제조방법
IL103560A0 (en) Stabilised antibodies
PT76267A (fr) Procede d'obtention de composes derives de l'acide 3-hydroxybu-tanoique et procede d'obtention de compositions pharmaceutiques contenant de l'acide 3-hydroxybutanoique ou un sel derive de cet acide
NZ214122A (en) Analgesic dynorphin-like hepta and octa and nona and deca peptides
JPS5785890A (en) Hydrocarbon-soluble polyamine-molybdenum composition
DE59208982D1 (de) Verfahren zur Reinigung von IgG-monoklonalen Antikörpern
NO934379L (no) Additiv med sporelementer, samt fremgangsmaate ved fremstilling derav
IL62198A0 (en) 3,4,5-trihydroxypiperidine compounds,their production and pharmaceutical compositions containing them
DE59205646D1 (de) Verfahren zur Gewinnung von Diacetylrhein
FI933546A (fi) Kemisk process
ATE189680T1 (de) Verfahren zur quantitativen aufreinigung von glycolipiden
GB1185618A (en) A Process for the Manufacture of Isoindole Derivatives
GB1375902A (en) Process for the preparation of unsaturated cycloaliphatic ketones
GB1427508A (en) Pyrido pyrimidine compounds
IT1210910B (it) Miglioramento del procedimento per preparare composti biarilici via copulazione di un'arilammina con un arene.
ES8407056A1 (es) Un procedimiento para la preparacion de heptahidrato de 7b-(2d-2-amino-2-carboxietiiitioacetamido-7&-metoxi-3-(1-metil- 1h-tetrazol-5-il)tiometil-3-cefem-4-carboxilato sodico.
SE8402172D0 (sv) Magnetisk kropp
JPS5562902A (en) Separation of endotoxin
JPS5538363A (en) Preparation of optically active n-mercaptoacyl-imino acid
SU1029554A1 (ru) Способ радиохимического выделени азота из облученных образцов
JPS5634633A (en) Preparation of s-sulfonated immunoglobulin rich in monomer
JPS5254261A (en) Suspension treating method