ATE9905T1 - Herstellung von immunoglobulin mit hohem monomer- anteil. - Google Patents

Herstellung von immunoglobulin mit hohem monomer- anteil.

Info

Publication number
ATE9905T1
ATE9905T1 AT80302770T AT80302770T ATE9905T1 AT E9905 T1 ATE9905 T1 AT E9905T1 AT 80302770 T AT80302770 T AT 80302770T AT 80302770 T AT80302770 T AT 80302770T AT E9905 T1 ATE9905 T1 AT E9905T1
Authority
AT
Austria
Prior art keywords
immunoglobulin
production
monomer
high content
monomer content
Prior art date
Application number
AT80302770T
Other languages
English (en)
Inventor
Tetsuro Sato
Akinobu Funatsu
Komei Ohashi
Shoji Ono
Tsunemasa Yoshida
Original Assignee
Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
Teijin Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Juridical Foundation The Chemo-Sero-Therapeutic Research Institute, Teijin Limited filed Critical Juridical Foundation The Chemo-Sero-Therapeutic Research Institute
Application granted granted Critical
Publication of ATE9905T1 publication Critical patent/ATE9905T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions
AT80302770T 1980-02-14 1980-08-12 Herstellung von immunoglobulin mit hohem monomer- anteil. ATE9905T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1737080A JPS56113713A (en) 1980-02-14 1980-02-14 Preparation of immunoglobulin with high content of monomer
EP80302770A EP0035616B1 (de) 1980-02-14 1980-08-12 Herstellung von Immunoglobulin mit hohem Monomer-Anteil

Publications (1)

Publication Number Publication Date
ATE9905T1 true ATE9905T1 (de) 1984-11-15

Family

ID=11942133

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80302770T ATE9905T1 (de) 1980-02-14 1980-08-12 Herstellung von immunoglobulin mit hohem monomer- anteil.

Country Status (7)

Country Link
US (1) US4384993A (de)
EP (1) EP0035616B1 (de)
JP (1) JPS56113713A (de)
AT (1) ATE9905T1 (de)
CA (1) CA1137413A (de)
DE (1) DE3069460D1 (de)
ZA (1) ZA81964B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362661A (en) * 1979-08-09 1982-12-07 Teijin Limited Immunoglobulin composition having a high monomer content, and process for production thereof
WO1984000891A1 (en) * 1982-08-30 1984-03-15 Baxter Travenol Lab Method for making gamma globulin-containing compositions
US4634417A (en) * 1982-12-06 1987-01-06 Georgetown University Process for treatment of tumors and apparatus therefor
DK166763C (da) * 1983-03-16 1993-07-12 Immuno Ag Immunoglobulin-g-holdig fraktion
US4732863A (en) * 1984-12-31 1988-03-22 University Of New Mexico PEG-modified antibody with reduced affinity for cell surface Fc receptors
US4597966A (en) * 1985-01-09 1986-07-01 Ortho Diagnostic Systems, Inc. Histidine stabilized immunoglobulin and method of preparation
JPH0662436B2 (ja) * 1986-05-19 1994-08-17 株式会社ミドリ十字 静注用免疫グロブリン製剤の製造方法
JPH04502914A (ja) * 1988-12-15 1992-05-28 セントユール，インコーポレイテッド 免疫グロブリンを可溶化するための塩基性アミノ酸の使用
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
US5219578A (en) * 1991-02-25 1993-06-15 Innovet, Inc. Composition and method for immunostimulation in mammals
US5514781A (en) * 1994-04-11 1996-05-07 Bayer Corporation Use of azoles as virucidal agents in solutions of biologically active proteins
EP0852951A1 (de) 1996-11-19 1998-07-15 Roche Diagnostics GmbH Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern
US6294171B2 (en) * 1999-09-14 2001-09-25 Milkhaus Laboratory, Inc. Methods for treating disease states comprising administration of low levels of antibodies
US6713058B2 (en) 1999-09-14 2004-03-30 Milkhaus Laboratory, Inc. Methods for alleviating symptoms associated with neuropathic conditions comprising administration of low levels of antibodies
US6187309B1 (en) * 1999-09-14 2001-02-13 Milkaus Laboratory, Inc. Method for treatment of symptoms of central nervous system disorders
US6436401B1 (en) 1999-09-14 2002-08-20 Milkhaus Laboratory, Inc. Methods for alleviating symptoms associated with diabetes and diabetic neuropathy comprising administration of low levels of antibodies

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3382227A (en) * 1967-01-30 1968-05-07 Pentex Inc Blood protein fractionation employing 2-ethoxy-6, 9-diamino-acridine-lactate
DE2001902C3 (de) * 1970-01-16 1978-10-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Reinigung und Fraktionierung von gelösten aktiven Proteinen
DE2508132C3 (de) * 1974-03-08 1980-10-16 Teijin Ltd., Osaka (Japan) Verfahren zur Herstellung von Humanimmunglobulin-Derivaten und parenteral applizierbare Lösung hiervon
US4118379A (en) * 1974-09-06 1978-10-03 Behringwerke Aktiengesellschaft Amidated immune globulins and process for preparing them
US4362661A (en) * 1979-08-09 1982-12-07 Teijin Limited Immunoglobulin composition having a high monomer content, and process for production thereof
JPS5625116A (en) * 1979-08-09 1981-03-10 Teijin Ltd Preparation of immunoglobulin having high content of monomer
JPS5625115A (en) * 1979-08-09 1981-03-10 Teijin Ltd Immunoglobulin composition
US4374763A (en) * 1979-09-17 1983-02-22 Morishita Pharmaceutical Co., Ltd. Method for producing gamma-globulin for use in intravenous administration and method for producing a pharmaceutical preparation thereof

Also Published As

Publication number Publication date
JPS6160817B2 (de) 1986-12-23
CA1137413A (en) 1982-12-14
US4384993A (en) 1983-05-24
ZA81964B (en) 1982-03-31
EP0035616B1 (de) 1984-10-17
DE3069460D1 (en) 1984-11-22
EP0035616A1 (de) 1981-09-16
JPS56113713A (en) 1981-09-07

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee