ZA816322B - N-oxides of n-oxacyclic-alkylpiperidines,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application - Google Patents

N-oxides of n-oxacyclic-alkylpiperidines,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application

Info

Publication number
ZA816322B
ZA816322B ZA816322A ZA816322A ZA816322B ZA 816322 B ZA816322 B ZA 816322B ZA 816322 A ZA816322 A ZA 816322A ZA 816322 A ZA816322 A ZA 816322A ZA 816322 B ZA816322 B ZA 816322B
Authority
ZA
South Africa
Prior art keywords
oxacyclic
alkylpiperidines
oxides
compounds
manufacture
Prior art date
Application number
ZA816322A
Other languages
English (en)
Inventor
Charles Ferdinand Huebner
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA816322B publication Critical patent/ZA816322B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA816322A 1980-09-12 1981-09-11 N-oxides of n-oxacyclic-alkylpiperidines,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application ZA816322B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/186,776 US4329348A (en) 1979-02-26 1980-09-12 N-Oxacyclic-alkylpiperidines as psychostimulants

Publications (1)

Publication Number Publication Date
ZA816322B true ZA816322B (en) 1982-09-29

Family

ID=22686246

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA816322A ZA816322B (en) 1980-09-12 1981-09-11 N-oxides of n-oxacyclic-alkylpiperidines,process for their manufacture,pharmaceutical preparations containing these compounds and their therapeutic application

Country Status (13)

Country Link
US (1) US4329348A (fr)
EP (1) EP0048218A1 (fr)
JP (1) JPS5781483A (fr)
AU (1) AU7516881A (fr)
DD (1) DD202292A5 (fr)
DK (1) DK405981A (fr)
ES (1) ES8301972A1 (fr)
FI (1) FI812811L (fr)
GB (1) GB2083813A (fr)
IL (1) IL63789A0 (fr)
NO (1) NO813110L (fr)
PT (1) PT73657B (fr)
ZA (1) ZA816322B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3124366A1 (de) * 1981-06-20 1982-12-30 Hoechst Ag, 6000 Frankfurt N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung
FR2579596B1 (fr) * 1985-03-26 1987-11-20 Inst Nat Sante Rech Med (imidazolyl-4) piperidines, leur preparation et leur application en therapeutique
US4957928A (en) * 1986-06-26 1990-09-18 Ciba-Geigy Corporation Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
JP3916092B2 (ja) * 1993-09-17 2007-05-16 杏林製薬株式会社 イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
ATE256125T1 (de) 1999-06-02 2003-12-15 Janssen Pharmaceutica Nv Aminoalkyl substituierte (benzodioxane, benzofurane oder benzopyrane) derivate
EP1187831B1 (fr) 1999-06-02 2004-10-13 Janssen Pharmaceutica N.V. Derives substitues de pyrrolidinyle, de piperidinyle ou d'homopiperidinyle (benzodioxane, benzofurane ou benzopyrane)
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) * 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6540733B2 (en) * 2000-12-29 2003-04-01 Corazon Technologies, Inc. Proton generating catheters and methods for their use in enhancing fluid flow through a vascular site occupied by a calcified vascular occlusion
CA2507026A1 (fr) * 2002-11-22 2004-06-10 Takeda Pharmaceutical Company Limited Derives d'imidazole, leur procede de production et d'utilisation
TWI396686B (zh) * 2004-05-21 2013-05-21 Takeda Pharmaceutical 環狀醯胺衍生物、以及其製品和用法
GB0526042D0 (en) * 2005-12-21 2006-02-01 Syngenta Participations Ag Chemical compounds
TWI457122B (zh) * 2007-07-20 2014-10-21 Orion Corp 作為用於治療周邊和中央神經系統疾病之alpha2C拮抗劑的2,3－二氫苯並[1,4]戴奧辛－2－基甲基衍生物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3513239A (en) * 1967-03-15 1970-05-19 Smithkline Corp Pharmaceutical compositions containing 2-aminoalkyl coumaran derivatives and methods of treating depression therewith
US3629267A (en) * 1968-10-28 1971-12-21 Smith Kline French Lab Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione
BE794333A (fr) 1972-01-20 1973-07-19 Wyeth John & Brother Ltd Composes heterocycliques azotes therapeutiques
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3869463A (en) * 1973-01-17 1975-03-04 Wyeth John & Brother Ltd N-phenyl derivatives of alkanoylamido piperidines
US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
ZA76475B (en) * 1975-03-10 1977-08-31 Ciba Geigy Ag Indolyalkylpiperidines
US4147786A (en) * 1976-02-02 1979-04-03 Ciba-Geigy Corporation 1-Indolylalkyl-3-or 4-trimethyleneurido-piperidines
GB1582239A (en) * 1976-12-11 1981-01-07 Wyeth John & Brother Ltd Piperidin-4-yl ureas and thioureas
GR71865B (fr) * 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel

Also Published As

Publication number Publication date
DK405981A (da) 1982-03-13
JPS5781483A (en) 1982-05-21
PT73657B (en) 1983-10-20
DD202292A5 (de) 1983-09-07
IL63789A0 (en) 1981-12-31
FI812811L (fi) 1982-03-13
ES505410A0 (es) 1983-01-01
AU7516881A (en) 1982-03-18
PT73657A (en) 1981-10-01
US4329348A (en) 1982-05-11
ES8301972A1 (es) 1983-01-01
EP0048218A1 (fr) 1982-03-24
GB2083813A (en) 1982-03-31
NO813110L (no) 1982-03-15

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