ZA816046B - Pyrazine derivatives,processes for their preparation,and pharmaceutical compositions containing these - Google Patents

Pyrazine derivatives,processes for their preparation,and pharmaceutical compositions containing these

Info

Publication number
ZA816046B
ZA816046B ZA816046A ZA816046A ZA816046B ZA 816046 B ZA816046 B ZA 816046B ZA 816046 A ZA816046 A ZA 816046A ZA 816046 A ZA816046 A ZA 816046A ZA 816046 B ZA816046 B ZA 816046B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
pyrazine derivatives
Prior art date
Application number
ZA816046A
Other languages
English (en)
Inventor
Rudolf Dr Hurnaus
Gerhart Dr Griss
Robert Dr Sauter
Wolfgang Dr Grell
Walter Prof Dr Kobinger
Ludwig Dr Pichler
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA816046B publication Critical patent/ZA816046B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA816046A 1980-09-02 1981-09-01 Pyrazine derivatives,processes for their preparation,and pharmaceutical compositions containing these ZA816046B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803032994 DE3032994A1 (de) 1980-09-02 1980-09-02 Neue pyrazino-azepine, deren herstellung und diese sie enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA816046B true ZA816046B (en) 1983-05-25

Family

ID=6110937

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA816046A ZA816046B (en) 1980-09-02 1981-09-01 Pyrazine derivatives,processes for their preparation,and pharmaceutical compositions containing these

Country Status (22)

Country Link
US (2) US4409220A (fi)
EP (1) EP0047412B1 (fi)
JP (1) JPS5777684A (fi)
AR (1) AR227683A1 (fi)
AT (1) ATE8630T1 (fi)
AU (1) AU7477281A (fi)
CA (1) CA1172631A (fi)
DD (1) DD201682A5 (fi)
DE (2) DE3032994A1 (fi)
DK (1) DK385381A (fi)
ES (1) ES8206525A1 (fi)
FI (1) FI812687L (fi)
GB (1) GB2084135B (fi)
GR (1) GR75003B (fi)
HU (1) HU185651B (fi)
IL (1) IL63709A (fi)
NO (1) NO812963L (fi)
NZ (1) NZ198225A (fi)
PH (1) PH17099A (fi)
PT (1) PT73608B (fi)
YU (1) YU210681A (fi)
ZA (1) ZA816046B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3032994A1 (de) * 1980-09-02 1982-04-22 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyrazino-azepine, deren herstellung und diese sie enthaltende arzneimittel
US7897595B2 (en) * 2006-05-26 2011-03-01 Forest Laboratories Holdings Limited Pyridoazepine derivatives
CA2753597A1 (en) 2009-02-27 2010-09-02 Boehringer Ingelheim International Gmbh Drug combinations containing pde4-inhibitors and nsaids
WO2011124524A1 (de) 2010-04-08 2011-10-13 Boehringer Ingelheim International Gmbh Arzneimittelkombinationen enthaltend pde4-inhibitoren und ep4-rezeptor-antagonisten

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1009477A (en) 1962-02-13 1965-11-10 Smith Kline French Lab Novel process for preparing heterocyclic compounds
ES431307A1 (es) * 1973-11-16 1976-09-01 Thomae Gmbh Dr K Procedimiento para la preparacion de nuevos derivados de quinoleina.
DE2357253A1 (de) * 1973-11-16 1975-05-22 Thomae Gmbh Dr K Neue chinolinderivate
US4022779A (en) * 1974-07-25 1977-05-10 E. R. Squibb & Sons, Inc. Amino derivatives of pyrido(3,4-b)pyrazine carboxylic acids and esters
DE2519258A1 (de) * 1975-04-30 1976-11-11 Thomae Gmbh Dr K Neue chinoxaline
DE2617101A1 (de) * 1976-04-17 1977-11-17 Thomae Gmbh Dr K Neue naphthyridine
IT7851496A0 (it) * 1977-10-31 1978-10-13 Sandoz Ag Menti pirazinobenzossazepine loro preparazione e loro impiego quali medica
EP0008864A1 (en) * 1978-08-15 1980-03-19 FISONS plc Pyridopyrazine and quinoxaline derivatives, processes for their preparation, and pharmaceutical compositions containing them
DE3032994A1 (de) * 1980-09-02 1982-04-22 Dr. Karl Thomae Gmbh, 7950 Biberach Neue pyrazino-azepine, deren herstellung und diese sie enthaltende arzneimittel

Also Published As

Publication number Publication date
DE3165064D1 (en) 1984-08-30
ES505095A0 (es) 1982-08-16
US4486433A (en) 1984-12-04
ES8206525A1 (es) 1982-08-16
NO812963L (no) 1982-03-03
EP0047412B1 (de) 1984-07-25
GB2084135B (en) 1984-08-22
EP0047412A1 (de) 1982-03-17
ATE8630T1 (de) 1984-08-15
PT73608B (de) 1983-10-19
US4409220A (en) 1983-10-11
CA1172631A (en) 1984-08-14
PH17099A (en) 1984-05-29
IL63709A (en) 1985-02-28
YU210681A (en) 1983-10-31
HU185651B (en) 1985-03-28
GB2084135A (en) 1982-04-07
DK385381A (da) 1982-03-03
PT73608A (de) 1981-10-01
FI812687L (fi) 1982-03-03
DD201682A5 (de) 1983-08-03
IL63709A0 (en) 1981-12-31
DE3032994A1 (de) 1982-04-22
NZ198225A (en) 1984-11-09
AR227683A1 (es) 1982-11-30
JPS5777684A (en) 1982-05-15
GR75003B (fi) 1984-07-12
AU7477281A (en) 1982-03-11

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