ZA814845B - Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor - Google Patents

Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor

Info

Publication number
ZA814845B
ZA814845B ZA814845A ZA814845A ZA814845B ZA 814845 B ZA814845 B ZA 814845B ZA 814845 A ZA814845 A ZA 814845A ZA 814845 A ZA814845 A ZA 814845A ZA 814845 B ZA814845 B ZA 814845B
Authority
ZA
South Africa
Prior art keywords
group
compounds
salts
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA814845A
Other languages
English (en)
Inventor
G Phillipps
C Williamson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA814845B publication Critical patent/ZA814845B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/34One oxygen atom
    • C07D239/36One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA814845A 1980-07-15 1981-07-15 Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor ZA814845B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8023063 1980-07-15

Publications (1)

Publication Number Publication Date
ZA814845B true ZA814845B (en) 1983-02-23

Family

ID=10514771

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA814845A ZA814845B (en) 1980-07-15 1981-07-15 Substituted pyrimidin-2-ones, the salts thereof, process for their preparation, pharmaceutical compositions containing them and a method therefor

Country Status (12)

Country Link
US (1) US4636509A (de)
EP (1) EP0044704B1 (de)
JP (1) JPS5740471A (de)
AT (1) ATE19627T1 (de)
AU (1) AU7300381A (de)
CA (1) CA1160226A (de)
DE (1) DE3174554D1 (de)
DK (1) DK315281A (de)
ES (2) ES503984A0 (de)
NO (1) NO812431L (de)
NZ (1) NZ197714A (de)
ZA (1) ZA814845B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58159479A (ja) * 1982-02-24 1983-09-21 ニユエガ−ド・アンド・コンパニ−・アクシエ/セルカペト 置換されたピリミジン−2−オン化合物
GB2135992B (en) * 1983-01-11 1986-09-24 Nyegaard & Co As Substituted pyrimidines and processes for their preparation
GB8420610D0 (en) * 1984-08-14 1984-09-19 Glaxo Group Ltd Chemical compounds
US4849426A (en) * 1987-05-15 1989-07-18 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents
US4853388A (en) * 1987-05-15 1989-08-01 Pearlman Dale L Method for treating psoriasis with cytotoxic agents
US4820711A (en) * 1987-05-15 1989-04-11 Pearlman Dale L Method for treating actinic keratosis with cytotoxic agents
US4855466A (en) * 1987-12-28 1989-08-08 E. R. Squibb & Sons, Inc. Purinyl cyclobutanes
US6334997B1 (en) 1994-03-25 2002-01-01 Isotechnika, Inc. Method of using deuterated calcium channel blockers
ATE372966T1 (de) * 1994-03-25 2007-09-15 Isotechnika Inc Verbesserung der effektivität von arzneimitteln duren deuterierung
EP1752452A4 (de) * 2004-06-04 2010-07-14 Astellas Pharma Inc Propan-1,3-dionderivat und dessen salz
TW200722420A (en) * 2005-03-31 2007-06-16 Astellas Pharma Inc Propane-1,3-dion derivative or salt thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1561290A (en) * 1975-10-16 1980-02-20 Nyegaard & Co As Pyrimid - 2 - ones
ES498337A0 (es) * 1980-01-07 1982-06-01 Nyegaard & Co As Un procedimiento para la preparacion de 5-halo-pirimidin-2- onas
GB2080301B (en) * 1980-07-15 1984-04-18 Glaxo Group Ltd Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them
GB2080300B (en) * 1980-07-15 1984-04-26 Glaxo Group Ltd Substituted pyrimidin-2-ones the salts thereof processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
NZ197714A (en) 1984-11-09
ES8307758A1 (es) 1983-07-01
NO812431L (no) 1982-01-18
US4636509A (en) 1987-01-13
ATE19627T1 (de) 1986-05-15
ES513177A0 (es) 1983-07-01
DE3174554D1 (en) 1986-06-12
DK315281A (da) 1982-01-16
ES8301473A1 (es) 1982-12-01
CA1160226A (en) 1984-01-10
ES503984A0 (es) 1982-12-01
AU7300381A (en) 1982-01-21
JPS5740471A (en) 1982-03-06
EP0044704A1 (de) 1982-01-27
EP0044704B1 (de) 1986-05-07

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