ZA806399B - New 2-hydroxyalkyl-3,4,5-trihydroxypiperidine compounds, their production and their medicinal use - Google Patents

New 2-hydroxyalkyl-3,4,5-trihydroxypiperidine compounds, their production and their medicinal use

Info

Publication number
ZA806399B
ZA806399B ZA00806399A ZA806399A ZA806399B ZA 806399 B ZA806399 B ZA 806399B ZA 00806399 A ZA00806399 A ZA 00806399A ZA 806399 A ZA806399 A ZA 806399A ZA 806399 B ZA806399 B ZA 806399B
Authority
ZA
South Africa
Prior art keywords
compounds
hydroxyalkyl
trihydroxypiperidine
new
production
Prior art date
Application number
ZA00806399A
Other languages
English (en)
Inventor
L Mueller
W Puls
G Kinast
R Sitt
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA806399B publication Critical patent/ZA806399B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/02—Acyclic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00806399A 1979-10-19 1980-10-17 New 2-hydroxyalkyl-3,4,5-trihydroxypiperidine compounds, their production and their medicinal use ZA806399B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792942365 DE2942365A1 (de) 1979-10-19 1979-10-19 2-hydroxyalkyl-3,4,5-trihydroxy-(pi)-peridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA806399B true ZA806399B (en) 1981-10-28

Family

ID=6083911

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00806399A ZA806399B (en) 1979-10-19 1980-10-17 New 2-hydroxyalkyl-3,4,5-trihydroxypiperidine compounds, their production and their medicinal use

Country Status (15)

Country Link
US (1) US4348402A (es)
EP (1) EP0027908B1 (es)
JP (2) JPS5665869A (es)
AT (1) ATE4642T1 (es)
AU (1) AU6319480A (es)
CA (1) CA1161439A (es)
DE (2) DE2942365A1 (es)
DK (1) DK441180A (es)
ES (1) ES8106891A1 (es)
FI (1) FI803264L (es)
GR (1) GR71207B (es)
HU (1) HU181203B (es)
IL (1) IL61285A (es)
NO (1) NO802939L (es)
ZA (1) ZA806399B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU582758B2 (en) * 1984-06-28 1989-04-13 Mect Corporation Sialic acid derivatives, galactose derivatives and method for producing the same
US4634765A (en) * 1984-12-18 1987-01-06 Merrell Dow Pharmaceuticals Inc. Homodisaccharide hypoglycemic agents
US5231185A (en) * 1985-11-19 1993-07-27 Cornell Research Foundation, Inc. Monosaccharide analog-based glycosidase inhibitors
DE3611841A1 (de) * 1986-04-09 1987-10-15 Bayer Ag Verfahren zur herstellung von 1-desoxynojirimycin und dessen n-derivaten
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
US5144037A (en) * 1988-11-03 1992-09-01 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-d-glucitol derivatives
US5221746A (en) * 1988-11-03 1993-06-22 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-D-glucitol derivatives
US5003072A (en) * 1988-11-03 1991-03-26 G. D. Searle & Co. 1,5-dideoxy-1,5-imino-D-glucitol derivatives
US5310745A (en) * 1988-11-03 1994-05-10 G. D. Searle & Co. Antiviral compounds
US5026713A (en) * 1989-08-29 1991-06-25 Monsanto Company 1,3-dideoxy-3-fluoronojirimycin which inhibits glycosidase activity
US5175168A (en) * 1989-07-27 1992-12-29 Monsanto Company Intermediates for 1,2-dideoxy-2-fluoronojirimycin
US5025021A (en) * 1989-07-27 1991-06-18 Monsanto Company 1,2-dideoxy-2-fluoronojirimycin as glycosidase inhibitors
US5218121A (en) * 1989-08-29 1993-06-08 Monsanto Company Synthesis of 1,3-dideoxy-3-fluoronojirimycin
US5130320A (en) * 1989-08-29 1992-07-14 Monsanto Company Glycosidase inhibiting 1,3-dideoxy-3-fluoronojirimycin
JPH0556770U (ja) * 1991-10-25 1993-07-27 井関農機株式会社 走行クロ−ラにおけるスライド装置
AU9646598A (en) * 1997-10-23 1999-05-10 Takeda Chemical Industries Ltd. Fused imidazopyridine derivatives, process for producing the same, and preparations containing the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555654A (en) * 1977-06-25 1979-11-14 Exxon Research Engineering Co Agricultural burner apparatus
GB1554117A (en) * 1976-12-23 1979-10-17 Bayer Ag Inhibitors for a-glucosidases
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
JPS5470955A (en) * 1977-11-15 1979-06-07 Baasatairu Mfg Ltd Rotary type combine
JPS54106477A (en) * 1978-02-03 1979-08-21 Nippon Shinyaku Co Ltd Moranoline derivative
GB2020278B (en) * 1978-05-03 1983-02-23 Nippon Shinyaku Co Ltd Moranoline dervitives
JPS5515365A (en) * 1978-07-20 1980-02-02 Mitsubishi Heavy Ind Ltd Hull remodelling method

Also Published As

Publication number Publication date
ES496038A0 (es) 1981-09-16
CA1161439A (en) 1984-01-31
FI803264L (fi) 1981-04-20
EP0027908A2 (de) 1981-05-06
GR71207B (es) 1983-04-11
HU181203B (en) 1983-06-28
NO802939L (no) 1981-04-21
IL61285A0 (en) 1980-12-31
DE2942365A1 (de) 1981-05-14
EP0027908B1 (de) 1983-09-14
JPS5665869A (en) 1981-06-03
JPS646191B2 (es) 1989-02-02
IL61285A (en) 1984-10-31
DE3064835D1 (en) 1983-10-20
AU6319480A (en) 1981-04-30
DK441180A (da) 1981-04-20
US4348402A (en) 1982-09-07
JPH01131156A (ja) 1989-05-24
EP0027908A3 (en) 1981-08-05
ATE4642T1 (de) 1983-09-15
ES8106891A1 (es) 1981-09-16

Similar Documents

Publication Publication Date Title
NZ208529A (en) 2-pyrimidinyl-1-piperazine derivatives and pharmaceutical compositions
IL58775A0 (en) Hydroxyethyl-azole compounds,their production and pharmaceutical compositions containing them
ZA806399B (en) New 2-hydroxyalkyl-3,4,5-trihydroxypiperidine compounds, their production and their medicinal use
IL58782A0 (en) Hydroxypropyl-triazole compounds,their production and pharmaceutical compositions containing them
FR2391215A1 (fr) Nouvelles imidazoazines et imidazodiazines, leur preparation et leur application en tant que medicaments
IL62198A0 (en) 3,4,5-trihydroxypiperidine compounds,their production and pharmaceutical compositions containing them
ZA803818B (en) New 1-alka-2,4-dienyl-2-hydroxymethyl-3,4,5-trihydroxypipeidine compounds, the production and their medicinal use
ES478048A1 (es) Procedimiento para la obtencion de difenil-imidazolil-meta- nos sustituidos.
ATE4117T1 (de) Pseudotrisaccharide, ihre herstellung und verwendung als arzneimittel.
IL66028A0 (en) Saturated aminocyclitol derivatives,their preparation and pharmaceutical compositions containing them
IL59295A0 (en) Dehydropeptide compounds,their production and pharmaceutical compositions containing them
IL59768A (en) Prostaglandin derivatives of the 6-keto-pge1 series,process for their preparation and pharmaceutical compositions containing them
IL58774A (en) Fluorenyl-azolylmethylcarbinol compounds,their production and pharmaceutical compositions containing them
IL65683A0 (en) Cyclic sulphenamide compounds,their production and pharmaceutical compositions containing them
ES471125A1 (es) Procedimiento para preparar derivados de 1-aminoindolina
EP0039814A3 (en) Imidazolyl-indene-thiophenes, process for their preparation and their use as medicaments
JPS5536485A (en) Nnaminoo3*4*55trihydoxypiperidines*their manufacture and use as drug