ZA80243B - Pyridoindole derivatives for use in therapy - Google Patents

Pyridoindole derivatives for use in therapy

Info

Publication number
ZA80243B
ZA80243B ZA00800243A ZA80243A ZA80243B ZA 80243 B ZA80243 B ZA 80243B ZA 00800243 A ZA00800243 A ZA 00800243A ZA 80243 A ZA80243 A ZA 80243A ZA 80243 B ZA80243 B ZA 80243B
Authority
ZA
South Africa
Prior art keywords
alk
compounds
cooalk
therapy
various substituents
Prior art date
Application number
ZA00800243A
Other languages
English (en)
Inventor
H Najer
C Morel
G Koletar
R Dupont
J Frost
P Lardenois
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA80243B publication Critical patent/ZA80243B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00800243A 1979-04-26 1980-01-15 Pyridoindole derivatives for use in therapy ZA80243B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7910654A FR2455044A1 (fr) 1979-04-26 1979-04-26 Pyrido-indoles et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ZA80243B true ZA80243B (en) 1980-12-31

Family

ID=9224797

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00800243A ZA80243B (en) 1979-04-26 1980-01-15 Pyridoindole derivatives for use in therapy

Country Status (15)

Country Link
US (2) US4272539A (es)
EP (1) EP0021857B1 (es)
JP (1) JPS55145687A (es)
AT (1) ATE2078T1 (es)
AU (1) AU528231B2 (es)
CA (1) CA1146942A (es)
DE (1) DE3061373D1 (es)
DK (1) DK16880A (es)
ES (2) ES8102124A1 (es)
FR (1) FR2455044A1 (es)
GR (1) GR74393B (es)
IL (1) IL59131A (es)
NO (1) NO794272L (es)
PT (1) PT70699A (es)
ZA (1) ZA80243B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57123180A (en) * 1980-12-17 1982-07-31 Schering Ag 3-substituted beta-carboline, manufacture and psychotropic drug containing same
DE3309596A1 (de) * 1982-08-05 1984-04-05 Basf Ag, 6700 Ludwigshafen 2-substituierte 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung als arzneimittel
DE3229215A1 (de) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1-(halogenalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung
US4719211A (en) * 1984-05-01 1988-01-12 American Home Products Corporation 2,3,4,9-tetrahydro-2-heteroarylalkyl-1H-pyrido(3,4-B)indoles having antihypertensive properties
JP2527319B2 (ja) * 1986-12-25 1996-08-21 川研ファインケミカル株式会社 ７―ブロモ―β―カルボリン誘導体の製造方法
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
FR2663935A1 (fr) * 1990-06-27 1992-01-03 Adir Nouveaux 1,2,3,4,5,6-hexahydroazepino [4,5-b] indoles et 1,2,3,4-tetrahydrobethacarbolines, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DE4104257A1 (de) * 1991-02-13 1992-08-20 Boehringer Ingelheim Kg Verwendung von anellierten tetrahydropyridinessigsaeurederivaten fuer die behandlung neurologischer erkrankungen
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
US5466688A (en) * 1994-10-20 1995-11-14 American Home Products Corporation Pyrido[3,4-B]indole derivatives as serotonergic agents
FR2796644B1 (fr) * 1999-07-23 2001-09-07 Adir Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB841225A (en) * 1957-09-12 1960-07-13 Roche Products Ltd Novel quinolizine derivatives and process for the manufacture of same
GB1055203A (en) * 1964-09-16 1967-01-18 Ici Ltd -ß-carboline derivatives, a process for their manufacture, and compositions containing them
US4091102A (en) * 1975-08-22 1978-05-23 Endo Laboratories, Inc. Anti-depressant trans-hexahydropyrido[3,4-b]indoles
EP0008249B1 (fr) * 1978-07-28 1981-08-26 Synthelabo Dérivés de fluorènes et fluoranthènes, leur procédé de préparation et leur application en thérapeutique
US4220774A (en) * 1978-10-26 1980-09-02 Omnium Chimique Vincadifformine synthesis process

Also Published As

Publication number Publication date
ES8105733A1 (es) 1981-06-16
EP0021857A1 (fr) 1981-01-07
CA1146942A (en) 1983-05-24
ATE2078T1 (de) 1983-01-15
ES487714A0 (es) 1980-12-16
DE3061373D1 (en) 1983-01-27
DK16880A (da) 1980-10-27
IL59131A0 (en) 1980-05-30
AU528231B2 (en) 1983-04-21
FR2455044B1 (es) 1982-05-21
FR2455044A1 (fr) 1980-11-21
GR74393B (es) 1984-06-28
US4272539A (en) 1981-06-09
NO794272L (no) 1980-10-28
IL59131A (en) 1983-10-31
PT70699A (fr) 1980-02-01
ES494263A0 (es) 1981-06-16
EP0021857B1 (fr) 1982-12-22
AU5463180A (en) 1980-10-30
ES8102124A1 (es) 1980-12-16
US4336256A (en) 1982-06-22
JPS55145687A (en) 1980-11-13

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