ZA796356B - New hydroxypropyl-triazole compounds, their production and their medicinal use - Google Patents

New hydroxypropyl-triazole compounds, their production and their medicinal use

Info

Publication number
ZA796356B
ZA796356B ZA00796356A ZA796356A ZA796356B ZA 796356 B ZA796356 B ZA 796356B ZA 00796356 A ZA00796356 A ZA 00796356A ZA 796356 A ZA796356 A ZA 796356A ZA 796356 B ZA796356 B ZA 796356B
Authority
ZA
South Africa
Prior art keywords
production
triazole compounds
hydroxypropyl
medicinal use
new
Prior art date
Application number
ZA00796356A
Other languages
English (en)
Inventor
E Regel
I Haller
K Buechel
M Plempel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA796356B publication Critical patent/ZA796356B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Lubricants (AREA)
  • Liquid Developers In Electrophotography (AREA)
ZA00796356A 1978-11-25 1979-11-23 New hydroxypropyl-triazole compounds, their production and their medicinal use ZA796356B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782851086 DE2851086A1 (de) 1978-11-25 1978-11-25 Hydroxypropyl-triazole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
ZA796356B true ZA796356B (en) 1980-12-31

Family

ID=6055560

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00796356A ZA796356B (en) 1978-11-25 1979-11-23 New hydroxypropyl-triazole compounds, their production and their medicinal use

Country Status (18)

Country Link
US (1) US4381306A (fi)
EP (1) EP0011768B1 (fi)
JP (1) JPS55108860A (fi)
AT (1) ATE324T1 (fi)
AU (1) AU536920B2 (fi)
CA (1) CA1130296A (fi)
DD (1) DD146824A5 (fi)
DE (2) DE2851086A1 (fi)
DK (1) DK152493C (fi)
ES (1) ES486279A1 (fi)
FI (1) FI65992C (fi)
HU (1) HU179414B (fi)
IE (1) IE48880B1 (fi)
IL (1) IL58782A (fi)
NO (1) NO793673L (fi)
NZ (1) NZ192195A (fi)
PH (1) PH16119A (fi)
ZA (1) ZA796356B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4927839A (en) * 1979-03-07 1990-05-22 Imperial Chemical Industries Plc Method of preventing fungal attack on wood, hides, leather or paint films using a triazole
US4551469A (en) * 1979-03-07 1985-11-05 Imperial Chemical Industries Plc Antifungal triazole ethanol derivatives
US4654332A (en) * 1979-03-07 1987-03-31 Imperial Chemical Industries Plc Heterocyclic compounds
AU542623B2 (en) * 1980-05-16 1985-02-28 Bayer Aktiengesellschaft 1-hydroxyethyl-azole derivatives
DE3018865A1 (de) * 1980-05-16 1981-11-26 Bayer Ag, 5090 Leverkusen Antimikrobielle mittel
NZ198085A (en) * 1980-08-18 1985-09-13 Ici Plc Regulation of plant growth with certain 2,2-di(hydrocarbyl)-1-(1,2,4-triazol-1-yl)ethan-2-ols
EP0046337A3 (en) * 1980-08-20 1982-09-15 Imperial Chemical Industries Plc Triazole compounds, a process for preparing them, their use as plant and pharmaceutical fungicides and as plant growth regulators and compositions containing them
EP0048548B1 (en) * 1980-08-28 1984-11-14 Imperial Chemical Industries Plc Pharmaceutical compositions of fungicidal triazole derivatives
AT375359B (de) * 1980-09-02 1984-07-25 Ici Plc Verfahren zur herstellung von neuen verbindungen
AU8314482A (en) * 1981-05-19 1982-11-25 Imperial Chemical Industries Plc 3-triazolyl(imidazolyl)-2,2 bis phenyl-propionamides
DE3232647A1 (de) * 1982-09-02 1984-03-08 Bayer Ag, 5090 Leverkusen Substituierte tert.-butanol-derivate, verfahren zu ihrer herstellung und diese enthaltende antimykotische mittel
DE3245504A1 (de) * 1982-12-09 1984-06-14 Bayer Ag, 5090 Leverkusen Fungizide mittel, deren herstellung und verwendung
DE3461637D1 (en) * 1983-02-16 1987-01-22 Pfizer Ltd Triazole antifungal agents
US5194427A (en) * 1987-11-09 1993-03-16 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
US5006513A (en) * 1987-11-09 1991-04-09 Miles Inc. Antimycotic compositions of nikkomycin compounds and azole antimycotica
ES2039273T3 (es) * 1987-11-09 1993-09-16 Bayer Ag Compuestos antimicoticos a base de combinaciones de nicomicina y azol antimicotico.
US5096889A (en) * 1987-11-09 1992-03-17 Bayer Ag Antimycotic compositions of nikkomycin compounds and azole antimycotics
EP0440608A1 (en) * 1987-12-17 1991-08-14 E.I. Du Pont De Nemours And Company Antifungal carbinols
US4914087A (en) * 1988-02-29 1990-04-03 Bayer Ag Nikkomycin derivatives, antimycotic compositions of nikkomycin derivatives and azole antimycotics
US5098920A (en) * 1990-05-04 1992-03-24 G. D. Searle & Co. 1h-substituted-1,2,4-triazole compounds and methods of use thereof for treatment of cardiovascular disorders
US5155117A (en) * 1991-04-12 1992-10-13 G. D. Searle & Co. 1-arylheteroarylalkyl substituted-1h-1,2,4-triazole compounds for treatment of circulatory disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4002763A (en) * 1972-09-26 1977-01-11 Bayer Aktiengesellschaft 1,2,4-Triazole antimycotic compositions and use thereof
DE2324424A1 (de) * 1973-05-15 1974-12-05 Bayer Ag Antimikrobielle mittel
DE2431407C2 (de) * 1974-06-29 1982-12-02 Bayer Ag, 5090 Leverkusen 1,2,4-Triazol-1-yl-alkanone und -alkanole, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Fungizide
GB1569267A (en) * 1975-12-16 1980-06-11 Ici Ltd Substituted propiophenones and herbicidal and fungicidal compositions containing them
DE2623129C3 (de) * 1976-05-22 1980-04-10 Nordmark-Werke Gmbh, 2000 Hamburg U-Diphenyl-3-(imidazol-l-yl) -propan-2-ole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2705679A1 (de) * 1977-02-11 1978-08-17 Bayer Ag Antimikrobielle mittel

Also Published As

Publication number Publication date
IL58782A (en) 1984-02-29
DK152493B (da) 1988-03-07
AU5317279A (en) 1980-05-29
EP0011768B1 (de) 1981-10-21
NO793673L (no) 1980-05-28
US4381306A (en) 1983-04-26
IL58782A0 (en) 1980-02-29
DD146824A5 (de) 1981-03-04
ES486279A1 (es) 1980-05-16
AU536920B2 (en) 1984-05-31
EP0011768A1 (de) 1980-06-11
DK152493C (da) 1988-07-25
JPS6258355B2 (fi) 1987-12-05
DE2961083D1 (en) 1981-12-24
FI65992B (fi) 1984-04-30
JPS55108860A (en) 1980-08-21
HU179414B (en) 1982-10-28
DK499679A (da) 1980-05-26
CA1130296A (en) 1982-08-24
ATE324T1 (de) 1981-11-15
FI65992C (fi) 1984-08-10
IE792241L (en) 1980-05-25
NZ192195A (en) 1981-10-19
FI793688A (fi) 1980-05-26
IE48880B1 (en) 1985-06-12
DE2851086A1 (de) 1980-06-04
PH16119A (en) 1983-06-30

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