ZA784475B - Piperazinopyrrolobenzodiazepines - Google Patents
PiperazinopyrrolobenzodiazepinesInfo
- Publication number
- ZA784475B ZA784475B ZA00784475A ZA784475A ZA784475B ZA 784475 B ZA784475 B ZA 784475B ZA 00784475 A ZA00784475 A ZA 00784475A ZA 784475 A ZA784475 A ZA 784475A ZA 784475 B ZA784475 B ZA 784475B
- Authority
- ZA
- South Africa
- Prior art keywords
- piperazinopyrrolobenzodiazepines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/333—Radicals substituted by oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83969677A | 1977-10-05 | 1977-10-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA784475B true ZA784475B (en) | 1979-07-25 |
Family
ID=25280422
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00784475A ZA784475B (en) | 1977-10-05 | 1978-08-08 | Piperazinopyrrolobenzodiazepines |
| ZA00785599A ZA785599B (en) | 1977-10-05 | 1978-10-04 | New piperazinopyrrolobenzodiazepines,process for their manufacture and pharmaceutical preparations containing them |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00785599A ZA785599B (en) | 1977-10-05 | 1978-10-04 | New piperazinopyrrolobenzodiazepines,process for their manufacture and pharmaceutical preparations containing them |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0001585B1 (xx) |
| JP (1) | JPS5461199A (xx) |
| AT (1) | AT368157B (xx) |
| AU (1) | AU521335B2 (xx) |
| CA (1) | CA1113934A (xx) |
| DD (1) | DD138774A5 (xx) |
| DE (1) | DE2860861D1 (xx) |
| DK (1) | DK441278A (xx) |
| ES (1) | ES473900A1 (xx) |
| FI (1) | FI63578C (xx) |
| HK (1) | HK2185A (xx) |
| HU (1) | HU179948B (xx) |
| IE (1) | IE47390B1 (xx) |
| IL (1) | IL55664A (xx) |
| NO (1) | NO150159C (xx) |
| NZ (1) | NZ188580A (xx) |
| SG (1) | SG38684G (xx) |
| ZA (2) | ZA784475B (xx) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4737496A (en) * | 1986-10-01 | 1988-04-12 | Ciba-Geigy Corporation | 1,3,4,16b-tetrahydro-2H,10H-indolo[2,1-c]pyrazino-[1,2-a][1,4]benzodiazepines useful as serotonin-2 receptor antagonists |
| CA2026925A1 (en) * | 1989-10-05 | 1991-04-06 | Hiroshi Fukumi | Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use |
| EP0539164A1 (en) * | 1991-10-23 | 1993-04-28 | Sankyo Company Limited | Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use |
| AUPP433398A0 (en) * | 1998-06-25 | 1998-07-16 | Australian National University, The | Compounds and processes |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3763183A (en) * | 1972-07-10 | 1973-10-02 | Sterling Drug Inc | 1,2,3,10,11,11a-hexahydro-5h-pyrrolo (2,1-c)(1,4)benzodiazepines |
| US3985732A (en) * | 1974-04-26 | 1976-10-12 | American Cyanamid Company | 1,2,3,11A-Tetrahydro-10-methyl-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5,11(10H)-diones |
| US3984562A (en) * | 1975-02-24 | 1976-10-05 | American Cyanamid Company | Substituted benzodiazepines and method of use |
| US4017492A (en) * | 1976-04-02 | 1977-04-12 | The Upjohn Company | As-triazinobenzodiazepin-1-ones |
| US4073784A (en) * | 1977-03-09 | 1978-02-14 | The Upjohn Company | Certain as-triazino 4,3-a! 1,4!benzodiazepine-1,2-dione compounds |
-
1978
- 1978-08-08 ZA ZA00784475A patent/ZA784475B/xx unknown
- 1978-09-29 IL IL55664A patent/IL55664A/xx unknown
- 1978-10-02 DE DE7878101052T patent/DE2860861D1/de not_active Expired
- 1978-10-02 FI FI782994A patent/FI63578C/fi not_active IP Right Cessation
- 1978-10-02 EP EP78101052A patent/EP0001585B1/de not_active Expired
- 1978-10-03 ES ES473900A patent/ES473900A1/es not_active Expired
- 1978-10-03 DD DD78208254A patent/DD138774A5/xx unknown
- 1978-10-03 CA CA312,550A patent/CA1113934A/en not_active Expired
- 1978-10-04 NZ NZ188580A patent/NZ188580A/xx unknown
- 1978-10-04 AT AT0715178A patent/AT368157B/de not_active IP Right Cessation
- 1978-10-04 ZA ZA00785599A patent/ZA785599B/xx unknown
- 1978-10-04 IE IE1985/78A patent/IE47390B1/en unknown
- 1978-10-04 HU HU78CI1862A patent/HU179948B/hu unknown
- 1978-10-04 NO NO783360A patent/NO150159C/no unknown
- 1978-10-04 AU AU40401/78A patent/AU521335B2/en not_active Expired
- 1978-10-04 DK DK441278A patent/DK441278A/da not_active Application Discontinuation
- 1978-10-05 JP JP12212178A patent/JPS5461199A/ja active Pending
-
1984
- 1984-05-23 SG SG386/84A patent/SG38684G/en unknown
-
1985
- 1985-01-10 HK HK21/85A patent/HK2185A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU521335B2 (en) | 1982-03-25 |
| DE2860861D1 (en) | 1981-10-29 |
| IL55664A (en) | 1982-02-28 |
| ATA715178A (de) | 1982-01-15 |
| FI782994A (fi) | 1979-04-06 |
| NO150159B (no) | 1984-05-21 |
| HK2185A (en) | 1985-01-18 |
| CA1113934A (en) | 1981-12-08 |
| SG38684G (en) | 1985-03-29 |
| AU4040178A (en) | 1980-04-17 |
| IL55664A0 (en) | 1978-12-17 |
| DD138774A5 (de) | 1979-11-21 |
| ZA785599B (en) | 1979-09-26 |
| IE47390B1 (en) | 1984-03-07 |
| DK441278A (da) | 1979-04-06 |
| IE781985L (en) | 1979-04-05 |
| JPS5461199A (en) | 1979-05-17 |
| AT368157B (de) | 1982-09-27 |
| NO150159C (no) | 1984-08-29 |
| ES473900A1 (es) | 1979-04-16 |
| EP0001585A1 (de) | 1979-05-02 |
| EP0001585B1 (de) | 1981-07-22 |
| FI63578C (fi) | 1983-07-11 |
| NO783360L (no) | 1979-04-06 |
| FI63578B (fi) | 1983-03-31 |
| NZ188580A (en) | 1981-12-15 |
| HU179948B (en) | 1983-01-28 |
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