ZA776131B - Monocyclic b-lactams with antibacterial activity - Google Patents

Monocyclic b-lactams with antibacterial activity

Info

Publication number
ZA776131B
ZA776131B ZA00776131A ZA776131A ZA776131B ZA 776131 B ZA776131 B ZA 776131B ZA 00776131 A ZA00776131 A ZA 00776131A ZA 776131 A ZA776131 A ZA 776131A ZA 776131 B ZA776131 B ZA 776131B
Authority
ZA
South Africa
Prior art keywords
lactams
monocyclic
antibacterial activity
antibacterial
activity
Prior art date
Application number
ZA00776131A
Other languages
English (en)
Inventor
R Hall
W Huffman
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of ZA776131B publication Critical patent/ZA776131B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00776131A 1976-11-15 1977-10-14 Monocyclic b-lactams with antibacterial activity ZA776131B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/742,149 US4144333A (en) 1976-11-15 1976-11-15 Monocyclic beta-lactams with antibacterial activity

Publications (1)

Publication Number Publication Date
ZA776131B true ZA776131B (en) 1978-06-28

Family

ID=24983681

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00776131A ZA776131B (en) 1976-11-15 1977-10-14 Monocyclic b-lactams with antibacterial activity

Country Status (22)

Country Link
US (1) US4144333A (it)
JP (1) JPS5363370A (it)
AU (1) AU514506B2 (it)
BE (1) BE860773A (it)
CA (1) CA1120935A (it)
CH (2) CH638781A5 (it)
DE (1) DE2751041A1 (it)
DK (1) DK497677A (it)
ES (2) ES464008A1 (it)
FI (1) FI773383A (it)
FR (1) FR2392006A1 (it)
GB (2) GB1594003A (it)
IE (1) IE45982B1 (it)
IL (1) IL53342A (it)
IT (1) IT1088885B (it)
LU (1) LU78497A1 (it)
NL (1) NL7712508A (it)
NO (1) NO150040C (it)
PH (1) PH22249A (it)
PT (1) PT67251B (it)
SE (1) SE7712645L (it)
ZA (1) ZA776131B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4257947A (en) * 1977-08-03 1981-03-24 Smithkline Corporation 3-Amino-2-hydroxy, halo or mercaptomethyl-4-oxoazetidines
DE3166235D1 (en) * 1980-02-14 1984-10-31 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
EP0187355A1 (en) 1981-09-23 1986-07-16 E.R. Squibb & Sons, Inc. Process for preparing beta-lactam antibiotics
FR2515182B1 (fr) * 1981-10-23 1986-05-09 Roussel Uclaf Nouveaux produits derives de l'acide 3-amino 2-oxo azetidine 1-sulfamique, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH563396A5 (it) * 1970-06-05 1975-06-30 Ciba Geigy Ag
US3943123A (en) * 1971-04-30 1976-03-09 Koninklijke Nederlandsche Gist-En Spiritusfabriek N.V. Novel beta-lactams and novel process
US3840556A (en) * 1971-05-28 1974-10-08 Lilly Co Eli Penicillin conversion by halogen electrophiles and anti-bacterials derived thereby
DE2204105A1 (de) * 1972-01-28 1973-08-02 Beecham Group Ltd Seco-penicilline und verfahren zu ihrer herstellung
US3920696A (en) * 1973-04-02 1975-11-18 Lilly Co Eli 2s-carboxyalkylthio-3r-imidoazetidin-4-ones and compounds useful in their preparation
US3917644A (en) * 1973-08-03 1975-11-04 Lilly Co Eli Azetidinesulfenic acids
US3901880A (en) * 1974-09-11 1975-08-26 Hoffmann La Roche (s)-alanyl-3-(+60 -(s)-chloro-3-(s)-hydroxy-2-oxo-azetidinylmethyl)-(s)-alanine
US4000154A (en) * 1975-09-03 1976-12-28 Smithkline Corporation 3-Substituted-6β-(amino- and acylamino)-7-oxo-1,3-diazabicyclo[3.2.0]-h

Also Published As

Publication number Publication date
IT1088885B (it) 1985-06-10
IL53342A0 (en) 1978-01-31
LU78497A1 (it) 1978-03-20
JPS5363370A (en) 1978-06-06
JPS6324990B2 (it) 1988-05-23
FI773383A (fi) 1978-05-16
FR2392006B1 (it) 1981-07-24
NO773900L (no) 1978-05-18
BE860773A (fr) 1978-05-16
AU514506B2 (en) 1981-02-12
NO150040B (no) 1984-04-30
PT67251A (en) 1977-12-01
PT67251B (en) 1979-04-16
DE2751041A1 (de) 1978-05-24
GB1594003A (en) 1981-07-30
CH641448A5 (de) 1984-02-29
SE7712645L (sv) 1978-05-16
GB1594004A (en) 1981-07-30
IE45982B1 (en) 1983-01-12
CH638781A5 (de) 1983-10-14
ES464008A1 (es) 1978-08-01
NO150040C (no) 1984-08-15
PH22249A (en) 1988-07-01
NL7712508A (nl) 1978-05-17
ES464000A1 (es) 1978-07-16
US4144333A (en) 1979-03-13
DK497677A (da) 1978-05-16
IE45982L (en) 1978-05-15
FR2392006A1 (fr) 1978-12-22
IL53342A (en) 1981-07-31
AU3058677A (en) 1979-05-17
CA1120935A (en) 1982-03-30

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