ZA74488B - New pyridine derivatives,process for their preparation and applications thereof - Google Patents
New pyridine derivatives,process for their preparation and applications thereofInfo
- Publication number
- ZA74488B ZA74488B ZA740488A ZA74488A ZA74488B ZA 74488 B ZA74488 B ZA 74488B ZA 740488 A ZA740488 A ZA 740488A ZA 74488 A ZA74488 A ZA 74488A ZA 74488 B ZA74488 B ZA 74488B
- Authority
- ZA
- South Africa
- Prior art keywords
- applications
- preparation
- pyridine derivatives
- new pyridine
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7303503A FR2215948B1 (fi) | 1973-02-01 | 1973-02-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA74488B true ZA74488B (en) | 1974-11-27 |
Family
ID=9114160
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA740488A ZA74488B (en) | 1973-02-01 | 1974-01-23 | New pyridine derivatives,process for their preparation and applications thereof |
Country Status (16)
Country | Link |
---|---|
US (1) | US4051141A (fi) |
JP (1) | JPS5231357B2 (fi) |
AT (1) | AT338261B (fi) |
AU (1) | AU473141B2 (fi) |
BE (1) | BE809812A (fi) |
CA (1) | CA1038871A (fi) |
CH (1) | CH593287A5 (fi) |
DK (1) | DK136651B (fi) |
ES (2) | ES422581A1 (fi) |
FR (1) | FR2215948B1 (fi) |
GB (1) | GB1445524A (fi) |
IL (3) | IL44061A (fi) |
NL (1) | NL7401237A (fi) |
PH (2) | PH11451A (fi) |
SE (2) | SE416203B (fi) |
ZA (1) | ZA74488B (fi) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2345150A2 (fr) * | 1975-08-06 | 1977-10-21 | Centre Etd Ind Pharma | Nouveaux derives de la thienopyridine, et leur application |
FR2313055A2 (fr) * | 1975-06-05 | 1976-12-31 | Parcor | Nouveaux derives substitues de la thieno-pyridine, leur procede de preparation et leurs applications |
FR2312246A1 (fr) * | 1975-05-28 | 1976-12-24 | Parcor | Derives de la tetrahydro-4,5,6,7 thieno (3,2-c) pyridine, leur procede de preparation et leurs applications |
FR2312247A1 (fr) * | 1975-05-30 | 1976-12-24 | Parcor | Derives de la thieno-pyridine, leur procede de preparation et leurs applications |
FR2315274A1 (fr) * | 1975-06-27 | 1977-01-21 | Parcor | Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications |
US4163852A (en) * | 1975-07-09 | 1979-08-07 | Parcor | Process for the preparation of tetrahydro-thieno[3,2-c]- and [2,3-c]pyridine derivatives |
JPS5283950A (en) * | 1976-01-02 | 1977-07-13 | Sentore Deechiyuude Puuru Rand | Medicine for disease derived from blood magma |
FR2338703A1 (fr) * | 1976-01-22 | 1977-08-19 | Parcor | Derives de thieno (3,2-c) pyridine, leur procede de preparation et leurs applications |
FR2376860A1 (fr) * | 1977-01-07 | 1978-08-04 | Parcor | Tetrahydro-4,5,6,7 thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application therapeutique |
GB2038625B (en) * | 1978-12-29 | 1983-01-12 | Parcor | Therapeutic composition having an antithrombotic and antiblood-platelet-aggregating activity |
FR2395028A2 (fr) * | 1977-06-22 | 1979-01-19 | Centre Etd Ind Pharma | Derives pyridiniques, leur preparation et leurs application therapeutique |
GB2038178B (en) * | 1978-12-29 | 1983-03-09 | Parcor | Antithrombotic therapeutic compsition |
US4464377A (en) * | 1977-06-22 | 1984-08-07 | BLANCHARD Jean | Anti-thrombotic therapeutic compositions |
FR2397417A1 (fr) * | 1977-07-12 | 1979-02-09 | Parcor | Procede de preparation de derives de la thienopyridine |
JPS5498337A (en) * | 1978-01-06 | 1979-08-03 | Dai Ichi Seiyaku Co Ltd | Anticarcinogenic and/or antimetastatic agent |
JPS54105236A (en) * | 1978-02-06 | 1979-08-18 | Dai Ichi Seiyaku Co Ltd | Antithrombogenetic agent for shunt and/or artificial blood vessel |
US4490377A (en) * | 1980-07-29 | 1984-12-25 | Syntex (U.S.A.) Inc. | Acid stabilized compositions of thieno-pyridine derived compounds |
US4400384A (en) * | 1980-10-06 | 1983-08-23 | Sanofi, S.A. | 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-c] pyridine methanesulfonate and other novel salts thereof |
US4321266A (en) * | 1980-10-06 | 1982-03-23 | Sanofi | 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine |
FR2495158A1 (fr) * | 1980-11-28 | 1982-06-04 | Sanofi Sa | Nouveau procede de preparation de derives de la tetrahydro-5, 6, 7, 7a 4h-thieno (3, 2-c) pyridinone-2 |
FR2495157A1 (fr) * | 1980-11-28 | 1982-06-04 | Sanofi Sa | Procede nouveau de preparation des tetrahydro-5, 6, 7, 7a 4h-thieno (3, 2-c) pyridinones-2 |
FR2495156A1 (fr) * | 1980-11-28 | 1982-06-04 | Sanofi Sa | Derives de la thieno-pyridinone, leur procede de preparation et leur application therapeutique |
FR2508442A1 (fr) * | 1981-06-30 | 1982-12-31 | Sanofi Sa | Procede de preparation d'ethylamines b-cyclo-substituees et produits ainsi obtenus |
FR2530247B1 (fr) * | 1982-07-13 | 1986-05-16 | Sanofi Sa | Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique |
IT8222600A0 (it) * | 1982-07-28 | 1982-07-28 | Pietro Tommaso Tessitore | Nuovi idrossibenzensolfonati della 5-(o-clorobenzil)-4,5,6,7-tetraidro tieno parentesi quadra aperta 3,2-c parentesi quadra chiusa piridina. |
JPS6044344U (ja) * | 1983-09-03 | 1985-03-28 | オムロン株式会社 | リレ−の駆動回路 |
FR2566775B1 (fr) * | 1984-06-27 | 1986-10-31 | Synthelabo | Derives de tetrahydro-4,5,6,7 furo ou 1h-pyrrolo(2,3-c)pyridine, leur preparation et leur application en therapeutique |
FR2570701B1 (fr) * | 1984-09-27 | 1987-05-22 | Synthelabo | Derives de furo(3,2-c)pyridines, leur preparation et leur application en therapeutique |
JPS6185391A (ja) * | 1984-10-03 | 1986-04-30 | Nisshin Flour Milling Co Ltd | 5−(2−クロロベンジル)−4,5,6,7−テトラヒドロチエノ〔3,2−c〕ピリジンの製造方法 |
GB8429087D0 (en) * | 1984-11-16 | 1984-12-27 | Scras | Thienopyridine derivatives |
FR2612777A1 (fr) * | 1987-03-26 | 1988-09-30 | Inst Nat Sante Rech Med | Composition medicamenteuse pour le traitement et la prevention de maladies dues a une cytotoxicite a mediation cellulaire, renfermant au moins un derive de la pyridine comme principe actif |
US4906756A (en) * | 1988-05-10 | 1990-03-06 | Syntex (U.S.A.) Inc. | 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives |
US5053393A (en) * | 1988-07-20 | 1991-10-01 | Monsanto Company | Novel platelet-aggregation inhibitor |
US4879313A (en) * | 1988-07-20 | 1989-11-07 | Mosanto Company | Novel platelet-aggregation inhibitors |
US5037808A (en) * | 1988-07-20 | 1991-08-06 | Monsanto Co. | Indolyl platelet-aggregation inhibitors |
US4992463A (en) * | 1988-07-20 | 1991-02-12 | Monsanto Company | Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation |
JPH02145581A (ja) * | 1988-10-11 | 1990-06-05 | Lonza Ag | 置換チエニルエチルアミンとその製造方法 |
GB8824400D0 (en) * | 1988-10-18 | 1988-11-23 | Glaxo Group Ltd | Chemical compounds |
US4997945A (en) * | 1990-01-25 | 1991-03-05 | Syntex (U.S.A.) Inc. | Carbamate salts of 2-(2'-thienyl)alkylamines |
FI101150B (fi) * | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
CA2087743C (en) * | 1992-02-06 | 1999-04-27 | Akio Odawara | Pharmaceutical composition for inhibiting platelet aggregation |
US5296603A (en) * | 1992-06-08 | 1994-03-22 | Fuji Photo Film Co., Ltd. | 3-amino-5-o-chlorobenzyl-4,5,6,7-tetrahydrothieno[3,2-c]-pyridine-2-carboxylic acid compounds |
US5294621A (en) * | 1992-10-07 | 1994-03-15 | Ortho Pharmaceutical Corporation | Thieno tetrahydropyridines useful as class III antiarrhythmic agents |
NZ334389A (en) * | 1996-08-28 | 2001-05-25 | Ube Industries | Cyclic amine derivatives |
US6043368A (en) * | 1996-09-04 | 2000-03-28 | Poli Industria Chimica, S.P.A. | Method of making thieno-pyridine derivatives |
US5872128A (en) * | 1997-10-15 | 1999-02-16 | Invamed, Inc. | Stabilized composition of ticlopidine hydrochloride |
KR100567950B1 (ko) | 1998-02-27 | 2006-04-05 | 상꾜 가부시키가이샤 | 환상 아미노화합물 |
US20080113025A1 (en) * | 1998-11-02 | 2008-05-15 | Elan Pharma International Limited | Compositions comprising nanoparticulate naproxen and controlled release hydrocodone |
US20090297597A1 (en) * | 1998-11-02 | 2009-12-03 | Gary Liversidge | Modified Release Ticlopidine Compositions |
KR100768034B1 (ko) | 1999-03-17 | 2007-10-17 | 다이이찌 세이야꾸 가부시기가이샤 | 의약 조성물 |
MXPA03005770A (es) | 2000-12-25 | 2003-09-10 | Sankyo Co | Composiciones medicinales que contienen aspirina. |
US6495691B1 (en) | 2001-07-06 | 2002-12-17 | Brantford Chemicals Inc. | Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives |
US20050192245A1 (en) * | 2002-07-18 | 2005-09-01 | Sankyo Company, Limited | Medicinal composition for treating arteriosclerosis |
CA2454015C (en) * | 2003-12-23 | 2009-11-24 | Brantford Chemicals Inc. | A process for the preparation of tetrahydrothieno [3,2-c] pyridine derivatives |
CA2611938A1 (en) * | 2005-06-13 | 2007-01-25 | Elan Corporation, Plc | Modified release ticlopidine compositions |
US20100062066A1 (en) * | 2006-11-14 | 2010-03-11 | Acusphere, Inc | Formulations of Tetrahydropyridine Antiplatelet Agents for Parenteral or Oral Administration |
EP1980563A1 (en) | 2007-04-09 | 2008-10-15 | BATTULA, Srinivasa Reddy | Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate |
US20090042869A1 (en) * | 2007-06-20 | 2009-02-12 | University Of Utah Research Foundation | SIGNAL-DEPENDENT SPLICING OF TISSUE FACTOR PRE-mRNA IN PLATELET CELLS |
CN102241690B (zh) | 2010-05-13 | 2015-08-12 | 天津药物研究院 | 一类含腈基的噻吩并吡啶酯类衍生物、其制备方法和用途 |
DE102014108210A1 (de) | 2014-06-11 | 2015-12-17 | Dietrich Gulba | Rodentizid |
EP4070658A1 (de) | 2021-04-06 | 2022-10-12 | BIORoxx GmbH | Verwendung von blutgerinnungshemmenden verbindungen als rodentizide |
-
1973
- 1973-02-01 FR FR7303503A patent/FR2215948B1/fr not_active Expired
-
1974
- 1974-01-15 CH CH49874A patent/CH593287A5/xx active Protection Beyond IP Right Term
- 1974-01-16 BE BE139867A patent/BE809812A/xx not_active IP Right Cessation
- 1974-01-22 IL IL44061A patent/IL44061A/en unknown
- 1974-01-22 IL IL49786A patent/IL49786A/en unknown
- 1974-01-23 ZA ZA740488A patent/ZA74488B/xx unknown
- 1974-01-24 ES ES422581A patent/ES422581A1/es not_active Expired
- 1974-01-28 SE SE7401036A patent/SE416203B/xx active Protection Beyond IP Right Term
- 1974-01-28 AT AT67874A patent/AT338261B/de not_active IP Right Cessation
- 1974-01-29 PH PH15449A patent/PH11451A/en unknown
- 1974-01-29 NL NL7401237A patent/NL7401237A/xx unknown
- 1974-01-30 AU AU65010/74A patent/AU473141B2/en not_active Expired
- 1974-01-30 GB GB439274A patent/GB1445524A/en not_active Expired
- 1974-01-31 JP JP49013559A patent/JPS5231357B2/ja not_active Expired
- 1974-01-31 CA CA191,469A patent/CA1038871A/en not_active Expired
- 1974-02-01 DK DK55574AA patent/DK136651B/da not_active IP Right Cessation
-
1976
- 1976-02-20 US US05/660,248 patent/US4051141A/en not_active Expired - Lifetime
- 1976-03-02 ES ES445702A patent/ES445702A1/es not_active Expired
- 1976-04-30 PH PH18386A patent/PH11759A/en unknown
- 1976-06-14 IL IL49786A patent/IL49786A0/xx unknown
-
1977
- 1977-03-17 SE SE7703028A patent/SE421624B/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
PH11451A (en) | 1978-02-01 |
IL49786A0 (en) | 1976-08-31 |
JPS5046688A (fi) | 1975-04-25 |
PH11759A (en) | 1978-06-27 |
AU6501074A (en) | 1975-07-31 |
US4051141A (en) | 1977-09-27 |
BE809812A (fr) | 1974-07-16 |
ATA67874A (de) | 1976-12-15 |
SE416203B (sv) | 1980-12-08 |
NL7401237A (fi) | 1974-08-05 |
GB1445524A (en) | 1976-08-11 |
JPS5231357B2 (fi) | 1977-08-13 |
DK136651B (da) | 1977-11-07 |
CH593287A5 (fi) | 1977-11-30 |
FR2215948A1 (fi) | 1974-08-30 |
SE7703028L (sv) | 1977-03-17 |
DE2404308B2 (de) | 1977-06-30 |
IL44061A0 (en) | 1974-05-16 |
FR2215948B1 (fi) | 1976-05-14 |
IL49786A (en) | 1977-06-30 |
IL44061A (en) | 1977-06-30 |
SE421624B (sv) | 1982-01-18 |
DE2404308A1 (de) | 1974-08-08 |
AT338261B (de) | 1977-08-10 |
ES422581A1 (es) | 1976-10-01 |
ES445702A1 (es) | 1977-06-01 |
DK136651C (fi) | 1978-04-17 |
AU473141B2 (en) | 1976-06-17 |
CA1038871A (en) | 1978-09-19 |
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