ZA72797B - Improvements relating to benzomorphanes,the acid addition salts as well as processes for the production thereof - Google Patents

Improvements relating to benzomorphanes,the acid addition salts as well as processes for the production thereof

Info

Publication number
ZA72797B
ZA72797B ZA720797A ZA72797A ZA72797B ZA 72797 B ZA72797 B ZA 72797B ZA 720797 A ZA720797 A ZA 720797A ZA 72797 A ZA72797 A ZA 72797A ZA 72797 B ZA72797 B ZA 72797B
Authority
ZA
South Africa
Prior art keywords
benzomorphanes
processes
production
well
acid addition
Prior art date
Application number
ZA720797A
Other languages
English (en)
Inventor
H Merz
K Stockhaus
A Langbein
H Wick
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ZA72797B publication Critical patent/ZA72797B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA720797A 1971-02-08 1972-02-07 Improvements relating to benzomorphanes,the acid addition salts as well as processes for the production thereof ZA72797B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2105743A DE2105743C3 (de) 1971-02-08 1971-02-08 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
ZA72797B true ZA72797B (en) 1973-10-31

Family

ID=5798071

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA720797A ZA72797B (en) 1971-02-08 1972-02-07 Improvements relating to benzomorphanes,the acid addition salts as well as processes for the production thereof

Country Status (2)

Country Link
DE (1) DE2105743C3 (xx)
ZA (1) ZA72797B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
JP5451611B2 (ja) 2007-07-26 2014-03-26 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１のサイクリックインヒビター
CA2704628C (en) 2007-11-16 2016-11-29 Boehringer Ingelheim International Gmbh Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
WO2009075835A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceutical, Inc CYCLIC UREA INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
US8598160B2 (en) 2008-02-15 2013-12-03 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
PL2300461T3 (pl) 2008-05-01 2013-09-30 Vitae Pharmaceuticals Inc Cykliczne inhibitory dehydrogenazy 11beta-hydroksysteroidów 1
JP5538365B2 (ja) 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
CL2009001058A1 (es) 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
US8765780B2 (en) 2008-05-13 2014-07-01 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CA2729998A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2687525B1 (en) 2008-07-25 2015-09-23 Boehringer Ingelheim International GmbH Cyclic inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
UA109255C2 (xx) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклічні інгібітори 11бета-гідроксистероїддегідрогенази 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
AR078887A1 (es) 2009-11-06 2011-12-07 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina y composiciones farmaceuticas que los contienen.
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
DE2105743C3 (de) 1979-11-29
DE2105743A1 (en) 1972-08-31
DE2105743B2 (de) 1979-04-05

Similar Documents

Publication Publication Date Title
ZA72797B (en) Improvements relating to benzomorphanes,the acid addition salts as well as processes for the production thereof
HK62577A (en) Basically substituted benzyl-phthalazinone derivatives, acid addition salts thereof and process for the production thereof
CA969180A (en) N-(furyl-methyl)-morphinanes, the acid addition salts as well as processes for production thereof
BE786840A (fr) Procede de preparation de 1,2,4-triazine -5-ones
CA969938A (en) 2-(furylmethyl)-6,7-benzomorphanes, the acid addition salts as well as processes for the production thereof
IL39735A0 (en) 3,20-dioxo-pregn-4-ene 21-carboxylic acid derivatives
YU137772A (en) Process for preparing 7p-amino-cephem-4-carboxylic acid compounds
IL41815A0 (en) Process for the production of 2,5-dichloro-3-nitro-benzoic acid
IE36597B1 (en) Process for preparing a 1,2-dihydrophthalazine
HU168381B (en) Process for production of derivatives of 8,12-diizoprostanic acid
ZA747790B (en) Process for the preparation of citric acid esters, citric acid or salts of citric acid
YU264480A (en) Process for obtaining the p-biphenylester of 11,15-bis-(tetrahydropyran-5-yloxy)-16-substituted tetranorprostadienic acid
YU39457B (en) Process for the manufacture of herbicidal 1,2-dialkyl-3,5-diphenylpirazole salts
AU4312972A (en) Substituted phenllimida zolidinones, the acid addition salts thereof and processes for their preparation
ZA721845B (en) Process for the production of optically active 1,4-benzodiazepinen
KE2800A (en) Process for the manufacture of 6-id(-)-alpha-aminophenylacetamido/-penicillanic acid
CA985649A (en) L-n-benzoyl-m or p-tyrosylanilides production by exzymatic reaction
CA975795A (en) Process for the production of trans-chrysanthemic acid
CA975379A (en) Process for the production of thiodipropionic acid compounds
PH9700A (en) A process for the manufacture of 20beta-hydroxy-9-oxo-1,2,3,4,10,19-hexanor-5,9-seco-pregnan-5-oic acid
IL39950A (en) Process for the production of citric acid by fermentation
IL38341A0 (en) Process for the manufacture of 2-chloroethane-phosphonic acid
BE765324A (fr) Procede de preparation d'un polychlorophenol, de haute purete
HU173178B (hu) Novyjj sposob poluchenija l-skobka-skobka zakryta-2-amino-3-skobka-3-zapjataja vverkh-4-zapjataja bberkh-digidroksi-fenil-skobka zakryta-propionnojj kisloty
YU34616B (en) Process for preparing 2,4,6-triiodo-3-acetyl-amino-benzoic acid