ZA704243B - Improvement in the preparation of 17-monoesters of 17alpha,21-dihydroxy-steroids - Google Patents

Improvement in the preparation of 17-monoesters of 17alpha,21-dihydroxy-steroids

Info

Publication number
ZA704243B
ZA704243B ZA704243A ZA704243A ZA704243B ZA 704243 B ZA704243 B ZA 704243B ZA 704243 A ZA704243 A ZA 704243A ZA 704243 A ZA704243 A ZA 704243A ZA 704243 B ZA704243 B ZA 704243B
Authority
ZA
South Africa
Prior art keywords
17alpha
monoesters
steroids
dihydroxy
improvement
Prior art date
Application number
ZA704243A
Other languages
English (en)
Inventor
A Ercoli
R Gardi
R Vitali
Original Assignee
Warner Lambert Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Pharmaceutical filed Critical Warner Lambert Pharmaceutical
Publication of ZA704243B publication Critical patent/ZA704243B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prevention Of Electric Corrosion (AREA)
ZA704243A 1969-06-26 1969-07-22 Improvement in the preparation of 17-monoesters of 17alpha,21-dihydroxy-steroids ZA704243B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT18717/69A IT1034011B (it) 1969-06-26 1969-06-26 Processo per la prapratzione di 17 monoesteri di 17 a 21 diossisteroidi per idrolisi die corpispondenti 17 21 ortoesteri ciclici a ph control lato

Publications (1)

Publication Number Publication Date
ZA704243B true ZA704243B (en) 1971-03-31

Family

ID=11153377

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA704243A ZA704243B (en) 1969-06-26 1969-07-22 Improvement in the preparation of 17-monoesters of 17alpha,21-dihydroxy-steroids

Country Status (11)

Country Link
US (1) US3755302A (cs)
CH (1) CH583252A5 (cs)
DK (1) DK129988B (cs)
FI (1) FI48186C (cs)
FR (1) FR2051186A5 (cs)
GB (1) GB1296458A (cs)
IT (1) IT1034011B (cs)
NL (1) NL162914C (cs)
NO (1) NO133936C (cs)
SE (1) SE356976B (cs)
ZA (1) ZA704243B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3857941A (en) * 1970-06-22 1974-12-31 Warner Lambert Co Pharmaceutical compositions and use of prednisolone 17-benzoate
GB1440063A (en) * 1972-08-11 1976-06-23 Glaxo Lab Ltd 17alpha-esters of 17alpha,21-dihydroxy-20-oxo-steroids
US3992422A (en) * 1975-08-14 1976-11-16 Schering Corporation Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes
EP0029151B1 (en) * 1979-11-16 1985-09-25 STEROSYNT Ltd. 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates
US6315985B1 (en) * 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
US6858596B2 (en) * 2000-08-05 2005-02-22 Smithkline Beecham Corporation Formulation containing anti-inflammatory androstane derivative
CA2417825C (en) * 2000-08-05 2008-07-22 Glaxo Group Limited 6.alpha., 9.alpha.-difluoro-17.alpha.-`(2-furanylcarboxyl)oxy!-11.beta.-hydroxy-16.alpha.-methyl-3-oxo-androst-1,4,-diene-17-carbothioic acid s-fluoromethyl ester as an anti-inflammatory agent
GB0019172D0 (en) * 2000-08-05 2000-09-27 Glaxo Group Ltd Novel compounds
US6777399B2 (en) 2000-08-05 2004-08-17 Smithkline Beecham Corporation Anti-inflammatory androstane derivative compositions
US6759398B2 (en) * 2000-08-05 2004-07-06 Smithkline Beecham Corporation Anti-inflammatory androstane derivative
MY137522A (en) * 2001-04-30 2009-02-27 Glaxo Group Ltd Novel anti-inflammatory androstane derivatives.
WO2002100879A1 (en) * 2001-06-12 2002-12-19 Glaxo Group Limited Novel anti-inflammatory 17.alpha.-heterocyclic-esters of 17.beta.carbothioate androstane derivatives
US20050175545A1 (en) * 2002-02-04 2005-08-11 Keith Biggadike Formulation for inhalation comprising a glucocorticoid and a beta 2-adrenoreceptor agonist
GB0202635D0 (en) * 2002-02-05 2002-03-20 Glaxo Wellcome Mfg Pte Ltd Formulation containing novel anti-inflammatory androstane derivative
GB2389530B (en) * 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
GB0507165D0 (en) * 2005-04-08 2005-05-18 Glaxo Group Ltd Novel crystalline pharmaceutical product
GB0615108D0 (en) * 2006-07-28 2006-09-06 Glaxo Group Ltd Novel formulations
CN102964414A (zh) * 2012-12-14 2013-03-13 中国科学院上海有机化学研究所 17位甾体羧酸酯的合成方法
CN115010198B (zh) * 2022-07-11 2023-05-09 西安国康瑞金制药有限公司 一种整合在倍他米松上氟中的废水处理工艺

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2897216A (en) * 1954-11-01 1959-07-28 Schering Corp Process for the preparation of steroidal dienes and intermediates obtained thereby
GB1070751A (en) * 1964-01-28 1967-06-01 Glaxo Lab Ltd 17-esters of 17-hydroxy-21-desoxy-steroids
US3345387A (en) * 1964-05-25 1967-10-03 Merck & Co Inc Process for producing 16beta-alkyl and 16beta-alkyl steroids of the pregnane series
US3499081A (en) * 1966-12-21 1970-03-03 Squibb & Sons Inc 9-chloroprogestational agents
IT1061787B (it) * 1967-03-01 1983-04-30 Vismara Francesco Spa Miglioramenti relativi alla preparazione di 17 benzoato di betametazone
US3455968A (en) * 1967-05-15 1969-07-15 Schering Corp 9alpha-halogeno-11beta-azido-steroids and methods for their manufacture

Also Published As

Publication number Publication date
NO133936C (cs) 1976-07-21
SE356976B (cs) 1973-06-12
DK129988C (cs) 1975-06-23
DK129988B (da) 1974-12-09
IT1034011B (it) 1979-09-10
US3755302A (en) 1973-08-28
FR2051186A5 (cs) 1971-04-02
DE2031205B2 (de) 1975-09-25
NL162914B (nl) 1980-02-15
FI48186B (cs) 1974-04-01
GB1296458A (cs) 1972-11-15
NO133936B (cs) 1976-04-12
FI48186C (fi) 1974-07-10
NL7009254A (cs) 1970-12-29
CH583252A5 (cs) 1976-12-31
DE2031205A1 (de) 1971-02-04
NL162914C (nl) 1980-07-15

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