ZA202204081B - Compressed nicotine lozenge - Google Patents
Compressed nicotine lozengeInfo
- Publication number
- ZA202204081B ZA202204081B ZA2022/04081A ZA202204081A ZA202204081B ZA 202204081 B ZA202204081 B ZA 202204081B ZA 2022/04081 A ZA2022/04081 A ZA 2022/04081A ZA 202204081 A ZA202204081 A ZA 202204081A ZA 202204081 B ZA202204081 B ZA 202204081B
- Authority
- ZA
- South Africa
- Prior art keywords
- module
- lozenge
- compressed
- nicotine lozenge
- nicotine
- Prior art date
Links
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title abstract 5
- 239000007937 lozenge Substances 0.000 title abstract 5
- 229960002715 nicotine Drugs 0.000 title abstract 5
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title abstract 5
- 150000005846 sugar alcohols Chemical class 0.000 abstract 2
- 230000006835 compression Effects 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/599,629 US11759419B2 (en) | 2019-10-11 | 2019-10-11 | Compressed nicotine lozenge |
| PCT/DK2020/050103 WO2021069036A1 (en) | 2019-10-11 | 2020-04-17 | Compressed nicotine lozenge |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA202204081B true ZA202204081B (en) | 2024-08-28 |
Family
ID=70464804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2022/04081A ZA202204081B (en) | 2019-10-11 | 2022-04-11 | Compressed nicotine lozenge |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11759419B2 (https=) |
| EP (2) | EP4445897A3 (https=) |
| JP (1) | JP7574286B2 (https=) |
| KR (1) | KR20220080165A (https=) |
| CN (1) | CN114630653B (https=) |
| AU (2) | AU2020363748B2 (https=) |
| BR (1) | BR112022006691A2 (https=) |
| CA (1) | CA3154225A1 (https=) |
| DK (1) | DK3923910T3 (https=) |
| ES (1) | ES2991040T3 (https=) |
| FI (1) | FI3923910T3 (https=) |
| MX (1) | MX2022004349A (https=) |
| MY (1) | MY206865A (https=) |
| PL (1) | PL3923910T3 (https=) |
| UA (1) | UA129748C2 (https=) |
| WO (1) | WO2021069036A1 (https=) |
| ZA (1) | ZA202204081B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220354785A1 (en) * | 2021-04-22 | 2022-11-10 | Nicoventures Trading Limited | Oral lozenge products |
| US12295412B2 (en) | 2022-01-28 | 2025-05-13 | Altria Client Services Llc | Oral pouch product |
| JP2026509969A (ja) * | 2023-01-27 | 2026-03-26 | フィリップ・モーリス・プロダクツ・ソシエテ・アノニム | 活性成分の経口送達のためのシステム |
| WO2024156323A1 (en) * | 2023-01-27 | 2024-08-02 | Fertin Pharma A/S | An adhesive oral disc for sustained release of cannabinoids |
| WO2025011727A1 (en) * | 2023-07-07 | 2025-01-16 | Fertin Pharma A/S | Dissolvable orally adhering nicotine tablet |
| KR20250033557A (ko) * | 2023-08-31 | 2025-03-10 | 주식회사 케이티앤지 | 니코틴 파우치 충진제 및 이의 제조방법 |
| KR20250033558A (ko) * | 2023-08-31 | 2025-03-10 | 주식회사 케이티앤지 | 니코틴 파우치 충진제 및 이의 제조방법 |
| KR20250033563A (ko) * | 2023-08-31 | 2025-03-10 | 주식회사 케이티앤지 | 니코틴 파우치 충진제 및 이의 제조방법 |
| EP4543417A1 (en) * | 2023-09-12 | 2025-04-30 | Fertin Pharma A/S | Orally disintegrating nicotine tablet for use under lip |
| CN121445113A (zh) * | 2024-08-02 | 2026-02-03 | 深圳市吉迩科技有限公司 | 一种尼古丁组合物及其制备方法、尼古丁制品 |
| WO2026057139A1 (en) * | 2024-09-12 | 2026-03-19 | Fertin Pharma A/S | Fast dissolvable solid oral dosage form |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CL2009001025A1 (es) | 2008-05-01 | 2010-09-24 | Smithkline Beecham Corp | Composicion de pastilla para chupar que comprende: a) un granulo patron con al menos: un agente tampon alcalino, un modificador de la disolucion y una carga, b) un principio activo de nicotina definido extragranular y al menos un agente tampon alcalino; procedimiento de preparacion; util para eliminar o reducir el uso de tabaco. |
| ES2592882T3 (es) * | 2008-10-14 | 2016-12-02 | Mcneil Ab | Forma de dosificación intra-oral de múltiples porciones y uso de la misma |
| CA2758618C (en) | 2009-04-24 | 2017-03-28 | Omya Development Ag | Particulate material for controlled release of active ingredients |
| UA112974C2 (uk) | 2010-09-16 | 2016-11-25 | Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид | Нікотиновмісна композиція (варіанти) |
| US20130078307A1 (en) | 2011-09-22 | 2013-03-28 | Niconovum Usa, Inc. | Nicotine-containing pharmaceutical composition |
| US9351936B2 (en) | 2013-10-03 | 2016-05-31 | Altria Client Services Llc | Nicotine lozenge |
| US20170172995A1 (en) * | 2015-09-08 | 2017-06-22 | Venkateswara Rao Repaka | Pharmaceutical compositions of Nicotine and process for preparation thereof |
| CA2916077C (en) | 2015-12-22 | 2023-06-20 | Euro-Pharm International Canada Inc. | Nicotine-containing solid oral formulations and uses thereof |
| RU2736072C1 (ru) | 2016-11-18 | 2020-11-11 | Фертин Фарма А/С | Таблетка, содержащая отдельное связывающее вещество и эритрит |
| US10543205B2 (en) | 2016-11-18 | 2020-01-28 | Fertin Pharma A/S | Oral delivery vehicle containing nicotine |
| ES2975449T3 (es) | 2017-05-22 | 2024-07-05 | Johnson & Johnson Consumer Inc | Forma farmacéutica de pastilla |
-
2019
- 2019-10-11 US US16/599,629 patent/US11759419B2/en active Active
-
2020
- 2020-04-17 KR KR1020227015714A patent/KR20220080165A/ko active Pending
- 2020-04-17 BR BR112022006691A patent/BR112022006691A2/pt unknown
- 2020-04-17 WO PCT/DK2020/050103 patent/WO2021069036A1/en not_active Ceased
- 2020-04-17 PL PL20721410.7T patent/PL3923910T3/pl unknown
- 2020-04-17 DK DK20721410.7T patent/DK3923910T3/da active
- 2020-04-17 AU AU2020363748A patent/AU2020363748B2/en active Active
- 2020-04-17 JP JP2022521536A patent/JP7574286B2/ja active Active
- 2020-04-17 MX MX2022004349A patent/MX2022004349A/es unknown
- 2020-04-17 CN CN202080070762.2A patent/CN114630653B/zh active Active
- 2020-04-17 ES ES20721410T patent/ES2991040T3/es active Active
- 2020-04-17 UA UAA202201332A patent/UA129748C2/uk unknown
- 2020-04-17 EP EP24192344.0A patent/EP4445897A3/en active Pending
- 2020-04-17 EP EP20721410.7A patent/EP3923910B1/en active Active
- 2020-04-17 CA CA3154225A patent/CA3154225A1/en active Pending
- 2020-04-17 FI FIEP20721410.7T patent/FI3923910T3/fi active
- 2020-04-17 MY MYPI2022001878A patent/MY206865A/en unknown
-
2022
- 2022-04-11 ZA ZA2022/04081A patent/ZA202204081B/en unknown
-
2023
- 2023-08-03 US US18/364,862 patent/US12478579B2/en active Active
-
2024
- 2024-03-15 AU AU2024201729A patent/AU2024201729B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP4445897A2 (en) | 2024-10-16 |
| MX2022004349A (es) | 2022-06-08 |
| PL3923910T3 (pl) | 2024-11-18 |
| AU2020363748B2 (en) | 2024-04-11 |
| US12478579B2 (en) | 2025-11-25 |
| ES2991040T3 (es) | 2024-12-02 |
| EP3923910A1 (en) | 2021-12-22 |
| FI3923910T3 (fi) | 2024-10-24 |
| DK3923910T3 (da) | 2024-11-11 |
| EP3923910B1 (en) | 2024-09-11 |
| UA129748C2 (uk) | 2025-07-23 |
| JP2022551314A (ja) | 2022-12-08 |
| BR112022006691A2 (pt) | 2022-07-12 |
| CN114630653B (zh) | 2026-01-30 |
| AU2024201729B2 (en) | 2025-10-09 |
| AU2020363748A1 (en) | 2022-04-28 |
| CA3154225A1 (en) | 2021-04-15 |
| EP4445897A3 (en) | 2025-01-15 |
| MY206865A (en) | 2025-01-10 |
| US20240000706A1 (en) | 2024-01-04 |
| KR20220080165A (ko) | 2022-06-14 |
| US11759419B2 (en) | 2023-09-19 |
| CN114630653A (zh) | 2022-06-14 |
| AU2024201729A1 (en) | 2024-04-04 |
| US20210106521A1 (en) | 2021-04-15 |
| JP7574286B2 (ja) | 2024-10-28 |
| WO2021069036A1 (en) | 2021-04-15 |
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