KR20220080165A - 압축 니코틴 로젠지 - Google Patents

압축 니코틴 로젠지 Download PDF

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Publication number
KR20220080165A
KR20220080165A KR1020227015714A KR20227015714A KR20220080165A KR 20220080165 A KR20220080165 A KR 20220080165A KR 1020227015714 A KR1020227015714 A KR 1020227015714A KR 20227015714 A KR20227015714 A KR 20227015714A KR 20220080165 A KR20220080165 A KR 20220080165A
Authority
KR
South Korea
Prior art keywords
lozenge
module
nicotine
water
compressed oral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020227015714A
Other languages
English (en)
Korean (ko)
Inventor
브루노 프롭스트고르 닐센
도르테 샤킹거 보센
하이디 지글러 브룬
켄트 알빈 닐슨
리케 프랭거-라스무센
Original Assignee
페르틴 파르마 에이/에스
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 페르틴 파르마 에이/에스 filed Critical 페르틴 파르마 에이/에스
Publication of KR20220080165A publication Critical patent/KR20220080165A/ko
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020227015714A 2019-10-11 2020-04-17 압축 니코틴 로젠지 Pending KR20220080165A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/599,629 US11759419B2 (en) 2019-10-11 2019-10-11 Compressed nicotine lozenge
US16/599,629 2019-10-11
PCT/DK2020/050103 WO2021069036A1 (en) 2019-10-11 2020-04-17 Compressed nicotine lozenge

Publications (1)

Publication Number Publication Date
KR20220080165A true KR20220080165A (ko) 2022-06-14

Family

ID=70464804

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020227015714A Pending KR20220080165A (ko) 2019-10-11 2020-04-17 압축 니코틴 로젠지

Country Status (17)

Country Link
US (2) US11759419B2 (https=)
EP (2) EP4445897A3 (https=)
JP (1) JP7574286B2 (https=)
KR (1) KR20220080165A (https=)
CN (1) CN114630653B (https=)
AU (2) AU2020363748B2 (https=)
BR (1) BR112022006691A2 (https=)
CA (1) CA3154225A1 (https=)
DK (1) DK3923910T3 (https=)
ES (1) ES2991040T3 (https=)
FI (1) FI3923910T3 (https=)
MX (1) MX2022004349A (https=)
MY (1) MY206865A (https=)
PL (1) PL3923910T3 (https=)
UA (1) UA129748C2 (https=)
WO (1) WO2021069036A1 (https=)
ZA (1) ZA202204081B (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025048200A1 (ko) * 2023-08-31 2025-03-06 주식회사 케이티앤지 니코틴 파우치 충진제 및 이의 제조방법
WO2025048224A1 (ko) * 2023-08-31 2025-03-06 주식회사 케이티앤지 니코틴 파우치 충진제 및 이의 제조방법
WO2025048222A1 (ko) * 2023-08-31 2025-03-06 주식회사 케이티앤지 니코틴 파우치 충진제 및 이의 제조방법

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220354785A1 (en) * 2021-04-22 2022-11-10 Nicoventures Trading Limited Oral lozenge products
US12295412B2 (en) 2022-01-28 2025-05-13 Altria Client Services Llc Oral pouch product
JP2026509969A (ja) * 2023-01-27 2026-03-26 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム 活性成分の経口送達のためのシステム
WO2024156323A1 (en) * 2023-01-27 2024-08-02 Fertin Pharma A/S An adhesive oral disc for sustained release of cannabinoids
WO2025011727A1 (en) * 2023-07-07 2025-01-16 Fertin Pharma A/S Dissolvable orally adhering nicotine tablet
EP4543417A1 (en) * 2023-09-12 2025-04-30 Fertin Pharma A/S Orally disintegrating nicotine tablet for use under lip
CN121445113A (zh) * 2024-08-02 2026-02-03 深圳市吉迩科技有限公司 一种尼古丁组合物及其制备方法、尼古丁制品
WO2026057139A1 (en) * 2024-09-12 2026-03-19 Fertin Pharma A/S Fast dissolvable solid oral dosage form

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2009001025A1 (es) 2008-05-01 2010-09-24 Smithkline Beecham Corp Composicion de pastilla para chupar que comprende: a) un granulo patron con al menos: un agente tampon alcalino, un modificador de la disolucion y una carga, b) un principio activo de nicotina definido extragranular y al menos un agente tampon alcalino; procedimiento de preparacion; util para eliminar o reducir el uso de tabaco.
ES2592882T3 (es) * 2008-10-14 2016-12-02 Mcneil Ab Forma de dosificación intra-oral de múltiples porciones y uso de la misma
CA2758618C (en) 2009-04-24 2017-03-28 Omya Development Ag Particulate material for controlled release of active ingredients
UA112974C2 (uk) 2010-09-16 2016-11-25 Джеі. Бі. Кемікалс Енд Фармасьютікалс Лімітид Нікотиновмісна композиція (варіанти)
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9351936B2 (en) 2013-10-03 2016-05-31 Altria Client Services Llc Nicotine lozenge
US20170172995A1 (en) * 2015-09-08 2017-06-22 Venkateswara Rao Repaka Pharmaceutical compositions of Nicotine and process for preparation thereof
CA2916077C (en) 2015-12-22 2023-06-20 Euro-Pharm International Canada Inc. Nicotine-containing solid oral formulations and uses thereof
RU2736072C1 (ru) 2016-11-18 2020-11-11 Фертин Фарма А/С Таблетка, содержащая отдельное связывающее вещество и эритрит
US10543205B2 (en) 2016-11-18 2020-01-28 Fertin Pharma A/S Oral delivery vehicle containing nicotine
ES2975449T3 (es) 2017-05-22 2024-07-05 Johnson & Johnson Consumer Inc Forma farmacéutica de pastilla

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2025048200A1 (ko) * 2023-08-31 2025-03-06 주식회사 케이티앤지 니코틴 파우치 충진제 및 이의 제조방법
WO2025048224A1 (ko) * 2023-08-31 2025-03-06 주식회사 케이티앤지 니코틴 파우치 충진제 및 이의 제조방법
WO2025048222A1 (ko) * 2023-08-31 2025-03-06 주식회사 케이티앤지 니코틴 파우치 충진제 및 이의 제조방법

Also Published As

Publication number Publication date
EP4445897A2 (en) 2024-10-16
MX2022004349A (es) 2022-06-08
PL3923910T3 (pl) 2024-11-18
AU2020363748B2 (en) 2024-04-11
US12478579B2 (en) 2025-11-25
ES2991040T3 (es) 2024-12-02
EP3923910A1 (en) 2021-12-22
FI3923910T3 (fi) 2024-10-24
DK3923910T3 (da) 2024-11-11
ZA202204081B (en) 2024-08-28
EP3923910B1 (en) 2024-09-11
UA129748C2 (uk) 2025-07-23
JP2022551314A (ja) 2022-12-08
BR112022006691A2 (pt) 2022-07-12
CN114630653B (zh) 2026-01-30
AU2024201729B2 (en) 2025-10-09
AU2020363748A1 (en) 2022-04-28
CA3154225A1 (en) 2021-04-15
EP4445897A3 (en) 2025-01-15
MY206865A (en) 2025-01-10
US20240000706A1 (en) 2024-01-04
US11759419B2 (en) 2023-09-19
CN114630653A (zh) 2022-06-14
AU2024201729A1 (en) 2024-04-04
US20210106521A1 (en) 2021-04-15
JP7574286B2 (ja) 2024-10-28
WO2021069036A1 (en) 2021-04-15

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