ZA202101462B - Blood plasma separation device - Google Patents

Blood plasma separation device

Info

Publication number
ZA202101462B
ZA202101462B ZA2021/01462A ZA202101462A ZA202101462B ZA 202101462 B ZA202101462 B ZA 202101462B ZA 2021/01462 A ZA2021/01462 A ZA 2021/01462A ZA 202101462 A ZA202101462 A ZA 202101462A ZA 202101462 B ZA202101462 B ZA 202101462B
Authority
ZA
South Africa
Prior art keywords
reservoir
fraction
blood plasma
region
separation device
Prior art date
Application number
ZA2021/01462A
Other languages
English (en)
Inventor
Marrinucci Dena
Ian Kleinemolen
Michael Abi-Samra Kameel
Original Assignee
Truvian Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Truvian Sciences Inc filed Critical Truvian Sciences Inc
Publication of ZA202101462B publication Critical patent/ZA202101462B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles or throttle valves
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0621—Control of the sequence of chambers filled or emptied
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Dispersion Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Public Health (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Centrifugal Separators (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • External Artificial Organs (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
ZA2021/01462A 2018-08-23 2021-03-03 Blood plasma separation device ZA202101462B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862722050P 2018-08-23 2018-08-23
US16/515,974 US11638918B2 (en) 2018-08-23 2019-07-18 Blood plasma separation device
PCT/US2019/044018 WO2020040945A1 (en) 2018-08-23 2019-07-30 Blood plasma separation device

Publications (1)

Publication Number Publication Date
ZA202101462B true ZA202101462B (en) 2024-03-27

Family

ID=69587179

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2021/01462A ZA202101462B (en) 2018-08-23 2021-03-03 Blood plasma separation device

Country Status (10)

Country Link
US (3) US11638918B2 (https=)
EP (1) EP3840878A1 (https=)
JP (1) JP2021536583A (https=)
CN (1) CN112689536A (https=)
AU (1) AU2019325155A1 (https=)
BR (1) BR112021003289A2 (https=)
CA (1) CA3110351A1 (https=)
MX (2) MX2021002115A (https=)
WO (1) WO2020040945A1 (https=)
ZA (1) ZA202101462B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114270178A (zh) 2019-02-26 2022-04-01 特鲁维安科学公司 测定装置及其使用方法
CN114302761A (zh) 2019-05-09 2022-04-08 特鲁维安科学公司 逆转血小板聚集的方法和组合物
CA3217713A1 (en) 2022-11-15 2024-05-15 Truvian Sciences, Inc. Systems and methods for drying reagents in multiwell plates
USD1116151S1 (en) 2023-05-03 2026-03-03 Truvian Sciences, Inc. Monolayer
US12287321B2 (en) 2023-09-08 2025-04-29 Truvian Sciences, Inc. Optical multianalyte detection

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040182795A1 (en) 2003-03-21 2004-09-23 Randel Dorian Apparatus and method for concentration of plasma from whole blood
US7220593B2 (en) 2002-10-03 2007-05-22 Battelle Memorial Institute Buffy coat separator float system and method
DE10313201A1 (de) * 2003-03-21 2004-10-07 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und mikrofluidisches Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Flüssigkeit, die Partikel enthält
CN101554601A (zh) * 2003-08-05 2009-10-14 贝克顿·迪金森公司 收集生物流体样品及处理选定成分的装置和方法
CN1603820A (zh) * 2003-09-29 2005-04-06 株式会社立佳 一种分离生物样品的仪器及其分离方法
JP4478776B2 (ja) * 2004-08-09 2010-06-09 独立行政法人物質・材料研究機構 血液分析装置及び血液分析方法
US7673758B2 (en) * 2005-08-10 2010-03-09 The Regents Of The University Of California Collection tubes apparatus, systems, and methods
GB201004072D0 (en) * 2010-03-11 2010-04-28 Turzi Antoine Process, tube and device for the preparation of wound healant composition
KR101197974B1 (ko) * 2011-11-01 2012-11-05 박현정 신속한 원심분리가 가능한 원심분리용 용기
KR20140136277A (ko) * 2013-05-20 2014-11-28 삼성전자주식회사 미세유동장치
JP6419130B2 (ja) * 2016-10-31 2018-11-07 シスメックス株式会社 測定用カートリッジおよび送液方法
CN106582908B (zh) * 2016-11-30 2019-09-13 深圳市达科为生物工程有限公司 一种富血小板血浆快速分离装置及方法

Also Published As

Publication number Publication date
EP3840878A1 (en) 2021-06-30
US20240197976A1 (en) 2024-06-20
AU2019325155A1 (en) 2021-04-15
JP2021536583A (ja) 2021-12-27
BR112021003289A2 (pt) 2021-05-18
US20200064329A1 (en) 2020-02-27
US11944735B2 (en) 2024-04-02
MX2021002115A (es) 2021-06-23
MX2024014368A (es) 2024-12-06
US11638918B2 (en) 2023-05-02
WO2020040945A1 (en) 2020-02-27
CN112689536A (zh) 2021-04-20
US20230241608A1 (en) 2023-08-03
CA3110351A1 (en) 2020-02-27

Similar Documents

Publication Publication Date Title
ZA202101462B (en) Blood plasma separation device
EP4527425A3 (en) Blood separation systems employing centrifugal and spinning membrane separation techniques
WO2012145414A3 (en) Apparatus and method for separating and concentrating fluids containing multiple components
SG11201902975TA (en) Plasma separation apparatus and plasma separation method
EP2863221A3 (en) Device and method of extracting high-concentration plasma from whole blood
GB2556582A (en) Microfluidic devices and methods of use thereof
MX2017002606A (es) Sistema y metodo para extraer gas de un pozo.
MY179012A (en) Emulsion extraction and processing from an oil/water separator
WO2009044552A1 (ja) 分析用デバイスとこれを使用する分析装置および分析方法
WO2010019317A3 (en) System and method for collecting plasma protein fractions from separated blood components
WO2018048754A8 (en) Systems and methods for extracting a sample from an ingestible device
WO2011052910A3 (ko) 원심분리 키트 및 이를 이용한 원심분리 방법
EP4600632A3 (en) System and method for collecting plasma
BR112014009877A2 (pt) aparelho de separação de fluido e método de separação seletiva para fluido misturado
MX2017001368A (es) Separacion de plasma asistido por vacio.
EP3782730A3 (en) Depth filtration device for separating specimen phases
CL2013000729A1 (es) Metodo para separar semillas endogamicas de una poblacion mixta de semillas hibridas y endogamicas, donde el metodo comprende, proporcionar una poblacion mixta de semillas hibridas y endogamicas, someter dichas semillas a un dispositivo que separa dicha poblacion mixta en una poblacion de semillas endogamicas, y una poblacion de semillas hibridas, donde la separacion de las semillas es a traves de luz del infrarrojo cercano; maquina.
WO2016153590A3 (en) Platelet rich plasma and bone marrow aspirate cell separation and removal methods and devices
WO2015177654A3 (en) A microfluidic device that separates cells
MX2011012222A (es) Metodo y aparato para separar sangre entera.
WO2017151883A3 (en) Biological fluid separation device
WO2011112831A3 (en) System and method for separating solids from fluids
MY185910A (en) Method for the separation of the isoprenic constituents of guayule
ZA202201084B (en) Cyclonic separator
EA201892547A1 (ru) Способ отделения биомассы от твердого продукта ферментации