ZA201800558B - Combination therapy using acamprosate and d-cycloserine - Google Patents

Combination therapy using acamprosate and d-cycloserine

Info

Publication number
ZA201800558B
ZA201800558B ZA201800558A ZA201800558A ZA201800558B ZA 201800558 B ZA201800558 B ZA 201800558B ZA 201800558 A ZA201800558 A ZA 201800558A ZA 201800558 A ZA201800558 A ZA 201800558A ZA 201800558 B ZA201800558 B ZA 201800558B
Authority
ZA
South Africa
Prior art keywords
acamprosate
cycloserine
combination therapy
therapy
combination
Prior art date
Application number
ZA201800558A
Other languages
English (en)
Inventor
Steven L Johns
Craig A Erickson
Original Assignee
Confluence Pharmaceuticals Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Confluence Pharmaceuticals Llc filed Critical Confluence Pharmaceuticals Llc
Publication of ZA201800558B publication Critical patent/ZA201800558B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
ZA201800558A 2015-08-04 2018-01-26 Combination therapy using acamprosate and d-cycloserine ZA201800558B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562200864P 2015-08-04 2015-08-04
PCT/US2016/045547 WO2017024129A1 (en) 2015-08-04 2016-08-04 Combination therapy using acamprosate and d-cycloserine

Publications (1)

Publication Number Publication Date
ZA201800558B true ZA201800558B (en) 2019-10-30

Family

ID=57944041

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA201800558A ZA201800558B (en) 2015-08-04 2018-01-26 Combination therapy using acamprosate and d-cycloserine

Country Status (11)

Country Link
US (2) US20180221315A1 (enExample)
EP (1) EP3331518A4 (enExample)
JP (2) JP2018526345A (enExample)
KR (1) KR20180034442A (enExample)
AU (2) AU2016303610A1 (enExample)
CA (1) CA2993614A1 (enExample)
HK (1) HK1255584A1 (enExample)
IL (1) IL257035A (enExample)
SG (1) SG10201914045QA (enExample)
WO (1) WO2017024129A1 (enExample)
ZA (1) ZA201800558B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017024129A1 (en) * 2015-08-04 2017-02-09 Confluence Pharmaceuticals, Llc Combination therapy using acamprosate and d-cycloserine
IL270654B2 (en) 2017-05-17 2024-07-01 Confluence Pharmaceuticals Llc Formulations of homotaurines and salts thereof
CN110996946A (zh) 2017-05-25 2020-04-10 格莱泰施有限责任公司 用于治疗创伤后应激障碍的制剂
US11291654B2 (en) * 2018-09-13 2022-04-05 Syneurx International (Taiwan) Corp. Formulations of cycloserine compounds and applications thereof
JP2025069475A (ja) * 2022-03-08 2025-05-01 ソシウム株式会社 Tdp-43の凝集の抑制剤、tdp-43が過剰発現している細胞の細胞死の抑制剤、及びtdp-43の凝集を伴う疾患の治療又は予防剤
CN119212703A (zh) * 2023-04-27 2024-12-27 寿协株式会社 肌萎缩性侧索硬化症的治疗剂或预防剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1073432T1 (de) * 1998-04-14 2002-02-07 The General Hospital Corp., Boston Verwendung von glycinrezeptoragonisten und glycinaufnahmeinhibitoren zur behandlung neuropsychiatrischer beschwerden
US20100216734A1 (en) * 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2010532331A (ja) * 2007-07-05 2010-10-07 アンセルム(アンスチチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル) 抗痙攣医薬組成物
DK2395990T3 (en) * 2009-02-12 2015-02-23 Univ Indiana Res & Tech Corp Material and methods for the treatment of developmental disorders comprising co-morbid and idiopathic autism
WO2010099217A1 (en) * 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
KR20130002292A (ko) * 2011-06-28 2013-01-07 주식회사 비보존 다중 타겟팅의 상승 효과를 유발하는 유효물질의 조합 및 그 용도
US10709668B2 (en) * 2015-05-04 2020-07-14 Confluence Pharmaceuticals, Llc Sprinkle formulations of acamprosate
WO2017024129A1 (en) * 2015-08-04 2017-02-09 Confluence Pharmaceuticals, Llc Combination therapy using acamprosate and d-cycloserine

Also Published As

Publication number Publication date
HK1255584A1 (zh) 2019-08-23
JP2018526345A (ja) 2018-09-13
KR20180034442A (ko) 2018-04-04
EP3331518A1 (en) 2018-06-13
US20180221315A1 (en) 2018-08-09
US20200360316A1 (en) 2020-11-19
SG10201914045QA (en) 2020-03-30
IL257035A (en) 2018-03-29
EP3331518A4 (en) 2019-04-03
WO2017024129A1 (en) 2017-02-09
JP2021152060A (ja) 2021-09-30
AU2016303610A1 (en) 2018-02-01
AU2022202218A1 (en) 2022-04-21
CA2993614A1 (en) 2017-02-09

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