ZA201603962B - Proline-rich peptides protective against s. pneumoniae - Google Patents

Proline-rich peptides protective against s. pneumoniae

Info

Publication number
ZA201603962B
ZA201603962B ZA2016/03962A ZA201603962A ZA201603962B ZA 201603962 B ZA201603962 B ZA 201603962B ZA 2016/03962 A ZA2016/03962 A ZA 2016/03962A ZA 201603962 A ZA201603962 A ZA 201603962A ZA 201603962 B ZA201603962 B ZA 201603962B
Authority
ZA
South Africa
Prior art keywords
pneumoniae
proline
protective against
rich peptides
peptides protective
Prior art date
Application number
ZA2016/03962A
Other languages
English (en)
Inventor
Arin Ghasparian
Armando Zuniga
Nina Geib
Marco Tamborini
Maja Jud
Gerd Pluschke
Nodarse Aniebrys Marrero
John Anthony Robinson
Original Assignee
Virometix Ag
Swiss Tropical And Public Health Inst
Univ Basel
Univ Zuerich
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virometix Ag, Swiss Tropical And Public Health Inst, Univ Basel, Univ Zuerich filed Critical Virometix Ag
Publication of ZA201603962B publication Critical patent/ZA201603962B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018—Lipids, e.g. in lipopeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73—Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16023—Virus like particles [VLP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2016/03962A 2013-12-03 2016-06-10 Proline-rich peptides protective against s. pneumoniae ZA201603962B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13195402 2013-12-03
PCT/EP2014/076313 WO2015082501A1 (en) 2013-12-03 2014-12-02 Proline-rich peptides protective against s. pneumoniae

Publications (1)

Publication Number Publication Date
ZA201603962B true ZA201603962B (en) 2020-02-26

Family

ID=49765797

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2016/03962A ZA201603962B (en) 2013-12-03 2016-06-10 Proline-rich peptides protective against s. pneumoniae

Country Status (12)

Country Link
US (2) US9943583B2 (enExample)
EP (1) EP3077410B1 (enExample)
JP (2) JP2017501990A (enExample)
KR (1) KR20160088323A (enExample)
CN (1) CN105793276A (enExample)
AU (1) AU2014359292B2 (enExample)
BR (1) BR112016012306A2 (enExample)
CA (1) CA2931570A1 (enExample)
HK (1) HK1225739A1 (enExample)
RU (1) RU2737638C2 (enExample)
WO (1) WO2015082501A1 (enExample)
ZA (1) ZA201603962B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3016815A1 (en) 2016-03-08 2017-09-14 KeMyth Biotech Co., Ltd. Use of pneumolysin peptides as antagonists against toll-like receptor 4 and methods of treating toll-like receptor 4 related diseases
CN110381992A (zh) * 2016-12-03 2019-10-25 Uab研究基金会 组合了肺炎球菌表面蛋白A的选择的α螺旋结构域和脯氨酸富集结构域的肺炎球菌疫苗
JP7356911B2 (ja) 2017-06-14 2023-10-05 ヴァイロメティックス アーゲー 呼吸器合胞体ウイルスに対する予防のための環状ペプチド
CN108559784B (zh) * 2018-07-06 2021-08-20 陕西省动物研究所 一种同时检测三种病原菌的三重pcr检测用引物、探针、试剂盒及检测方法
CA3121724A1 (en) 2018-12-20 2020-06-25 Virometix Ag Lipopeptide building blocks and synthetic virus-like particles
TWI739358B (zh) * 2019-03-25 2021-09-11 免疫功坊股份有限公司 帶有金屬結合區的複合多肽及其分子構建體
CA3130470A1 (en) * 2019-03-29 2020-10-08 Yoshikazu Yuki Pneumococcal surface proteins
WO2021260176A1 (en) 2020-06-25 2021-12-30 Virometix Ag Synthetic epitopes of betacoronaviruses
US20230355737A1 (en) 2020-09-28 2023-11-09 Dbv Technologies Particle comprising an rsv-f protein for use in rsv vaccination
CN121693342A (zh) 2023-07-12 2026-03-17 维罗迈科斯股份公司 肺炎球菌抗原的组合物
WO2025242657A1 (en) 2024-05-21 2025-11-27 Shape Biopharmaceuticals Ag Lipopeptide building blocks and aggregates

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US4663160A (en) * 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
GB8704647D0 (en) 1987-02-27 1987-04-01 Guy S & St Thomas S Hospitals Vaccine
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
US5391712A (en) 1991-08-30 1995-02-21 Beckman Instruments, Inc. Non-hemolytic streptolysin O variants
GB9202219D0 (en) * 1992-02-03 1992-03-18 Connaught Lab A synthetic heamophilus influenzae conjugate vaccine
US6251405B1 (en) * 1995-06-07 2001-06-26 Connaught Laboratories, Inc. Immunological combination compositions and methods
JP2000511769A (ja) 1996-04-02 2000-09-12 スミスクライン・ビーチャム・コーポレイション 新規化合物
JP2000508178A (ja) 1996-05-14 2000-07-04 スミスクライン・ビーチャム・コーポレイション 新規化合物
US6096863A (en) 1996-08-23 2000-08-01 Regents Of The University Of Minnesota Self-assembling amphiphiles for construction of peptide secondary structures
ATE348887T1 (de) 1996-10-31 2007-01-15 Human Genome Sciences Inc Streptococcus pneumoniae antigene und impfstoffe
US5980898A (en) 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
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CN1285753A (zh) 1997-12-02 2001-02-28 鲍德杰克特疫苗公司 透皮给药微粒疫苗组合物
IT1320157B1 (it) 2000-01-27 2003-11-18 Combistone Italia S P A Piano e/o rivestimento per arredamento e procedimento per la suaproduzione.
US7939087B2 (en) 2000-10-27 2011-05-10 Novartis Vaccines And Diagnostics, Inc. Nucleic acids and proteins from Streptococcus groups A & B
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
CN101124237A (zh) 2001-04-13 2008-02-13 惠氏 酿脓链球菌的表面蛋白
GB0210128D0 (en) 2002-05-02 2002-06-12 Chiron Spa Nucleic acids and proteins from streptococcus groups A & B
PT1551357E (pt) 2002-09-13 2014-10-10 Novartis Vaccines & Diagnostic Vacina contra os estreptococos do grupo b
WO2005002619A2 (en) 2003-06-26 2005-01-13 Chiron Corporation Immunogenic compositions for chlamydia trachomatis
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JP5276598B2 (ja) * 2006-12-09 2013-08-28 ウニヴェルジテート チューリッヒ プロレクトラート エムエヌヴェー コイルドコイル構造を有するリポペプチドビルディングブロック、リポペプチドヘリックスバンドル、合成ウイルス様粒子、および医薬製剤
SG10201600435UA (en) 2011-01-20 2016-02-26 Genocea Biosciences Inc Vaccines And Compositions Against Streptococcus Pneumoniae

Also Published As

Publication number Publication date
US9943583B2 (en) 2018-04-17
HK1225739A1 (zh) 2017-09-15
CN105793276A (zh) 2016-07-20
WO2015082501A1 (en) 2015-06-11
AU2014359292A1 (en) 2016-06-23
KR20160088323A (ko) 2016-07-25
RU2737638C2 (ru) 2020-12-01
CA2931570A1 (en) 2015-06-11
US20180256698A1 (en) 2018-09-13
US20160324947A1 (en) 2016-11-10
EP3077410A1 (en) 2016-10-12
EP3077410B1 (en) 2021-02-03
JP2017501990A (ja) 2017-01-19
BR112016012306A2 (pt) 2017-09-26
AU2014359292B2 (en) 2019-02-28
JP2020073487A (ja) 2020-05-14

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