ZA201503594B - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
ZA201503594B
ZA201503594B ZA2015/03594A ZA201503594A ZA201503594B ZA 201503594 B ZA201503594 B ZA 201503594B ZA 2015/03594 A ZA2015/03594 A ZA 2015/03594A ZA 201503594 A ZA201503594 A ZA 201503594A ZA 201503594 B ZA201503594 B ZA 201503594B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compositions
pharmaceutical
compositions
Prior art date
Application number
ZA2015/03594A
Other languages
English (en)
Inventor
Andrew Spaltenstein
Brian Alvin Johns
Shenshen Cai
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of ZA201503594B publication Critical patent/ZA201503594B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
ZA2015/03594A 2012-12-14 2015-05-21 Pharmaceutical compositions ZA201503594B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261737177P 2012-12-14 2012-12-14
PCT/US2013/075196 WO2014093941A1 (en) 2012-12-14 2013-12-14 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ZA201503594B true ZA201503594B (en) 2018-11-28

Family

ID=50935020

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2015/03594A ZA201503594B (en) 2012-12-14 2015-05-21 Pharmaceutical compositions

Country Status (20)

Country Link
US (2) US9795619B2 (cg-RX-API-DMAC7.html)
EP (1) EP2931285A4 (cg-RX-API-DMAC7.html)
JP (1) JP2016503030A (cg-RX-API-DMAC7.html)
KR (1) KR20150093819A (cg-RX-API-DMAC7.html)
CN (1) CN104902905A (cg-RX-API-DMAC7.html)
AU (1) AU2013358897B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015013695A2 (cg-RX-API-DMAC7.html)
CA (1) CA2893959A1 (cg-RX-API-DMAC7.html)
CL (1) CL2015001660A1 (cg-RX-API-DMAC7.html)
CR (1) CR20150313A (cg-RX-API-DMAC7.html)
EA (1) EA201590862A1 (cg-RX-API-DMAC7.html)
HK (1) HK1209638A1 (cg-RX-API-DMAC7.html)
IL (1) IL238807A0 (cg-RX-API-DMAC7.html)
MA (1) MA38182A1 (cg-RX-API-DMAC7.html)
MX (1) MX2015007563A (cg-RX-API-DMAC7.html)
PE (1) PE20151326A1 (cg-RX-API-DMAC7.html)
PH (1) PH12015501156A1 (cg-RX-API-DMAC7.html)
SG (2) SG10201704467SA (cg-RX-API-DMAC7.html)
WO (1) WO2014093941A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201503594B (cg-RX-API-DMAC7.html)

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JO3387B1 (ar) 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
US9795619B2 (en) * 2012-12-14 2017-10-24 Glaxosmithkline Llc Pharmaceutical compositions
AU2013361401C1 (en) 2012-12-21 2018-08-09 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their pharmaceutical use
US9637516B2 (en) 2012-12-31 2017-05-02 Hetero Research Foundation Betulinic acid proline derivatives as HIV inhibitors
NO2865735T3 (cg-RX-API-DMAC7.html) 2013-07-12 2018-07-21
EP3019503B1 (en) 2013-07-12 2017-09-06 Gilead Sciences, Inc. Polycyclic-carbamoylpyridone compounds and their use for the treatment of hiv infections
NO2717902T3 (cg-RX-API-DMAC7.html) 2014-06-20 2018-06-23
TW201613936A (en) 2014-06-20 2016-04-16 Gilead Sciences Inc Crystalline forms of(2R,5S,13aR)-8-hydroxy-7,9-dioxo-n-(2,4,6-trifluorobenzyl)-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide
TWI744723B (zh) 2014-06-20 2021-11-01 美商基利科學股份有限公司 多環型胺甲醯基吡啶酮化合物之合成
US20170129916A1 (en) 2014-06-26 2017-05-11 Hetero Research Foundation Novel betulinic proline imidazole derivatives as hiv inhibitors
KR20170056702A (ko) * 2014-09-26 2017-05-23 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 지효성 약제학적 조성물
TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
MA40886B1 (fr) 2015-02-09 2020-03-31 Hetero Research Foundation Nouveau triterpénone en c-3 avec des dérivés d'amide inverse en c-28 en tant qu'inhibiteurs du vih
WO2016147099A2 (en) 2015-03-16 2016-09-22 Hetero Research Foundation C-3 novel triterpenone with c-28 amide derivatives as hiv inhibitors
PT3466490T (pt) 2015-04-02 2020-12-24 Gilead Sciences Inc Compostos de carbamoilpiridona policíclicos e sua utilização farmacêutica
WO2018042331A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
WO2018042332A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
EP3654980A1 (en) 2017-07-21 2020-05-27 VIIV Healthcare Company Regimens for treating hib infections and aids

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WO2003011254A1 (en) * 2001-07-31 2003-02-13 Capricorn Pharma Inc. Amorphous drug beads
US20080206161A1 (en) * 2002-10-25 2008-08-28 Dov Tamarkin Quiescent foamable compositions, steroids, kits and uses thereof
US20050142205A1 (en) * 2003-07-18 2005-06-30 Julia Rashba-Step Methods for encapsulating small spherical particles prepared by controlled phase separation
US20060019934A1 (en) * 2004-05-20 2006-01-26 Saxena Brij B Anti-HIV-1 activity of betulinol derivatives
TW200628161A (en) 2004-11-12 2006-08-16 Panacos Pharmaceuticals Inc Novel betulin derivatives, preparation thereof and use thereof
CN1682740A (zh) * 2005-03-11 2005-10-19 中国药科大学 五环三萜类化合物在制备糖原磷酸化酶抑制剂中的应用
US20090023698A1 (en) 2005-03-29 2009-01-22 Krasutsky Pavel A Methods of manufacturing bioactive 3-esters of betulinic aldehyde and betulinic acid
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FI121468B (fi) 2006-06-07 2010-11-30 Valtion Teknillinen Betuliiniperäiset yhdisteet antimikrobisina aineina
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CZ301318B6 (cs) 2008-11-13 2010-01-13 Univerzita Palackého v Olomouci 2-Deoxyglykosidy triterpenoidu, zpusob jejich prípravy a jejich použití jako lécivo
MX383683B (es) * 2008-12-11 2025-03-11 Shionogi & Co Sintesis de inhibidores de integrasa de vih de carbamoil-piridona e intermediarios.
US8802727B2 (en) 2009-07-14 2014-08-12 Hetero Research Foundation, Hetero Drugs Limited Pharmaceutically acceptable salts of betulinic acid derivatives
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CN102883608A (zh) * 2010-02-11 2013-01-16 葛兰素史密丝克莱恩有限责任公司 白桦脂醇衍生物
TWI577377B (zh) * 2010-09-16 2017-04-11 Ｖｉｉｖ醫療保健公司 醫藥組合物
WO2013020246A1 (en) 2011-08-08 2013-02-14 Glaxosmithkline Llc Methylene derivatives of betulin
WO2013020245A1 (en) 2011-08-08 2013-02-14 Glaxosmithkline Llc Carbonyl derivatives of betulin
CA2859032A1 (en) 2011-12-14 2013-06-20 Glaxosmithkline Llc Propenoate derivatives of betulin
JO3387B1 (ar) * 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
US20150209273A1 (en) 2012-08-28 2015-07-30 Glaxosmithkline Llc Pharmaceutical Compositions
US9795619B2 (en) * 2012-12-14 2017-10-24 Glaxosmithkline Llc Pharmaceutical compositions
KR20170056702A (ko) 2014-09-26 2017-05-23 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 지효성 약제학적 조성물

Also Published As

Publication number Publication date
IL238807A0 (en) 2015-06-30
EP2931285A4 (en) 2016-06-01
PH12015501156A1 (en) 2015-08-10
WO2014093941A1 (en) 2014-06-19
AU2013358897A1 (en) 2015-07-02
AU2013358897B2 (en) 2017-01-05
CL2015001660A1 (es) 2015-10-02
CN104902905A (zh) 2015-09-09
HK1209638A1 (en) 2016-04-08
EA201590862A1 (ru) 2016-05-31
BR112015013695A2 (pt) 2017-07-11
CA2893959A1 (en) 2014-06-19
MA38182A1 (fr) 2018-04-30
US20150313917A1 (en) 2015-11-05
EP2931285A1 (en) 2015-10-21
CR20150313A (es) 2015-10-19
US9795619B2 (en) 2017-10-24
MX2015007563A (es) 2015-10-14
KR20150093819A (ko) 2015-08-18
US20180042944A1 (en) 2018-02-15
JP2016503030A (ja) 2016-02-01
SG10201704467SA (en) 2017-06-29
SG11201503807TA (en) 2015-06-29
PE20151326A1 (es) 2015-10-12

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