CL2015001660A1 - Composicion farmaceutica oral de accion prolongada (pap) que comprende un compuesto derivado de betulina en forma de microparticulas y encapsulado en un polimero, y un sistema tensoactivo que comprende un tensoactivo, un estabilizador y una sal amortiguadora; metodo para la prevencion y el tratamiento de una infeccion por vih. - Google Patents

Composicion farmaceutica oral de accion prolongada (pap) que comprende un compuesto derivado de betulina en forma de microparticulas y encapsulado en un polimero, y un sistema tensoactivo que comprende un tensoactivo, un estabilizador y una sal amortiguadora; metodo para la prevencion y el tratamiento de una infeccion por vih.

Info

Publication number
CL2015001660A1
CL2015001660A1 CL2015001660A CL2015001660A CL2015001660A1 CL 2015001660 A1 CL2015001660 A1 CL 2015001660A1 CL 2015001660 A CL2015001660 A CL 2015001660A CL 2015001660 A CL2015001660 A CL 2015001660A CL 2015001660 A1 CL2015001660 A1 CL 2015001660A1
Authority
CL
Chile
Prior art keywords
surfactant
betulin
pap
microparticles
encapsulated
Prior art date
Application number
CL2015001660A
Other languages
English (en)
Spanish (es)
Inventor
Brian Alvin Johns
Shenshen Cai
Andrew Spaltenstein
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of CL2015001660A1 publication Critical patent/CL2015001660A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
CL2015001660A 2012-12-14 2015-06-12 Composicion farmaceutica oral de accion prolongada (pap) que comprende un compuesto derivado de betulina en forma de microparticulas y encapsulado en un polimero, y un sistema tensoactivo que comprende un tensoactivo, un estabilizador y una sal amortiguadora; metodo para la prevencion y el tratamiento de una infeccion por vih. CL2015001660A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261737177P 2012-12-14 2012-12-14

Publications (1)

Publication Number Publication Date
CL2015001660A1 true CL2015001660A1 (es) 2015-10-02

Family

ID=50935020

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2015001660A CL2015001660A1 (es) 2012-12-14 2015-06-12 Composicion farmaceutica oral de accion prolongada (pap) que comprende un compuesto derivado de betulina en forma de microparticulas y encapsulado en un polimero, y un sistema tensoactivo que comprende un tensoactivo, un estabilizador y una sal amortiguadora; metodo para la prevencion y el tratamiento de una infeccion por vih.

Country Status (20)

Country Link
US (2) US9795619B2 (cg-RX-API-DMAC7.html)
EP (1) EP2931285A4 (cg-RX-API-DMAC7.html)
JP (1) JP2016503030A (cg-RX-API-DMAC7.html)
KR (1) KR20150093819A (cg-RX-API-DMAC7.html)
CN (1) CN104902905A (cg-RX-API-DMAC7.html)
AU (1) AU2013358897B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015013695A2 (cg-RX-API-DMAC7.html)
CA (1) CA2893959A1 (cg-RX-API-DMAC7.html)
CL (1) CL2015001660A1 (cg-RX-API-DMAC7.html)
CR (1) CR20150313A (cg-RX-API-DMAC7.html)
EA (1) EA201590862A1 (cg-RX-API-DMAC7.html)
HK (1) HK1209638A1 (cg-RX-API-DMAC7.html)
IL (1) IL238807A0 (cg-RX-API-DMAC7.html)
MA (1) MA38182A1 (cg-RX-API-DMAC7.html)
MX (1) MX2015007563A (cg-RX-API-DMAC7.html)
PE (1) PE20151326A1 (cg-RX-API-DMAC7.html)
PH (1) PH12015501156A1 (cg-RX-API-DMAC7.html)
SG (2) SG10201704467SA (cg-RX-API-DMAC7.html)
WO (1) WO2014093941A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201503594B (cg-RX-API-DMAC7.html)

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TWI695003B (zh) 2014-12-23 2020-06-01 美商基利科學股份有限公司 多環胺甲醯基吡啶酮化合物及其醫藥用途
MA40886B1 (fr) 2015-02-09 2020-03-31 Hetero Research Foundation Nouveau triterpénone en c-3 avec des dérivés d'amide inverse en c-28 en tant qu'inhibiteurs du vih
WO2016147099A2 (en) 2015-03-16 2016-09-22 Hetero Research Foundation C-3 novel triterpenone with c-28 amide derivatives as hiv inhibitors
PT3466490T (pt) 2015-04-02 2020-12-24 Gilead Sciences Inc Compostos de carbamoilpiridona policíclicos e sua utilização farmacêutica
WO2018042331A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
WO2018042332A1 (en) * 2016-08-31 2018-03-08 Glaxosmithkline Intellectual Property (No.2) Limited Combinations and uses and treatments thereof
EP3654980A1 (en) 2017-07-21 2020-05-27 VIIV Healthcare Company Regimens for treating hib infections and aids

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US9795619B2 (en) * 2012-12-14 2017-10-24 Glaxosmithkline Llc Pharmaceutical compositions
KR20170056702A (ko) 2014-09-26 2017-05-23 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 지효성 약제학적 조성물

Also Published As

Publication number Publication date
IL238807A0 (en) 2015-06-30
EP2931285A4 (en) 2016-06-01
PH12015501156A1 (en) 2015-08-10
WO2014093941A1 (en) 2014-06-19
AU2013358897A1 (en) 2015-07-02
AU2013358897B2 (en) 2017-01-05
CN104902905A (zh) 2015-09-09
HK1209638A1 (en) 2016-04-08
EA201590862A1 (ru) 2016-05-31
BR112015013695A2 (pt) 2017-07-11
CA2893959A1 (en) 2014-06-19
MA38182A1 (fr) 2018-04-30
US20150313917A1 (en) 2015-11-05
EP2931285A1 (en) 2015-10-21
CR20150313A (es) 2015-10-19
US9795619B2 (en) 2017-10-24
MX2015007563A (es) 2015-10-14
KR20150093819A (ko) 2015-08-18
US20180042944A1 (en) 2018-02-15
JP2016503030A (ja) 2016-02-01
SG10201704467SA (en) 2017-06-29
SG11201503807TA (en) 2015-06-29
PE20151326A1 (es) 2015-10-12
ZA201503594B (en) 2018-11-28

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