ZA201405598B - Method for preparing compound by novel michael addition reaction using water or various acids as additive - Google Patents

Method for preparing compound by novel michael addition reaction using water or various acids as additive

Info

Publication number
ZA201405598B
ZA201405598B ZA2014/05598A ZA201405598A ZA201405598B ZA 201405598 B ZA201405598 B ZA 201405598B ZA 2014/05598 A ZA2014/05598 A ZA 2014/05598A ZA 201405598 A ZA201405598 A ZA 201405598A ZA 201405598 B ZA201405598 B ZA 201405598B
Authority
ZA
South Africa
Prior art keywords
additive
water
addition reaction
michael addition
preparing compound
Prior art date
Application number
ZA2014/05598A
Other languages
English (en)
Inventor
Hee Bong Lee
Ji Eun An
Bong Chan Kim
Ae Ri Park
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of ZA201405598B publication Critical patent/ZA201405598B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58Preparation of carboxylic acid halides
    • C07C51/64Separation; Purification; Stabilisation; Use of additives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C07B37/02Addition
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C67/347Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/48Separation; Purification; Stabilisation; Use of additives
    • C07C67/62Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA2014/05598A 2012-02-03 2014-07-29 Method for preparing compound by novel michael addition reaction using water or various acids as additive ZA201405598B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120011317 2012-02-03
PCT/KR2013/000829 WO2013115595A1 (ko) 2012-02-03 2013-02-01 물 또는 다양한 산을 첨가제로 이용한 새로운 마이클-첨가 반응을 통하여 화합물을 제조하는 방법

Publications (1)

Publication Number Publication Date
ZA201405598B true ZA201405598B (en) 2015-09-30

Family

ID=48905559

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/05598A ZA201405598B (en) 2012-02-03 2014-07-29 Method for preparing compound by novel michael addition reaction using water or various acids as additive

Country Status (16)

Country Link
KR (1) KR101539761B1 (enExample)
CN (1) CN104159884B (enExample)
AU (1) AU2013215796B2 (enExample)
BR (1) BR112014018985B1 (enExample)
CL (1) CL2014002029A1 (enExample)
CO (1) CO7030967A2 (enExample)
EA (1) EA026411B1 (enExample)
MA (1) MA35906B1 (enExample)
MX (1) MX355336B (enExample)
MY (1) MY168411A (enExample)
PE (1) PE20142331A1 (enExample)
PH (1) PH12014501704B1 (enExample)
SG (1) SG11201404396TA (enExample)
TN (1) TN2014000329A1 (enExample)
WO (1) WO2013115595A1 (enExample)
ZA (1) ZA201405598B (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9774740B2 (en) 2008-01-28 2017-09-26 Afiniti Europe Technologies Limited Techniques for benchmarking pairing strategies in a contact center system
CN108191647B (zh) * 2018-02-22 2020-09-29 江苏尚莱特医药化工材料有限公司 2,2-二氟二羧酸二烷基酯的合成方法
CN113149823B (zh) * 2021-03-29 2023-12-08 上海青平药业有限公司 一种2-r1戊酸的制备方法
CN113354495A (zh) * 2021-05-20 2021-09-07 上海应用技术大学 一种二氟酮羰基取代不对称腈类化合物及其制备与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS573159B2 (enExample) * 1973-12-05 1982-01-20
EP0188256B1 (en) * 1985-01-14 1991-08-21 NeoRx Metal radionuclide labeled proteins for diagnosis and therapy
ATE387421T1 (de) * 2001-03-07 2008-03-15 Firmenich & Cie Verfahren zur herstellung von michael-addukten
WO2009082134A2 (en) * 2007-12-21 2009-07-02 Lg Life Sciences, Ltd. Dipeptidyl peptidase-iv inhibiting compounds, methods of preparing the same, and pharmaceutical compositions containing the same as active agent

Also Published As

Publication number Publication date
EA201491463A1 (ru) 2014-11-28
BR112014018985A8 (pt) 2017-07-11
KR20130090360A (ko) 2013-08-13
SG11201404396TA (en) 2015-06-29
TN2014000329A1 (en) 2015-12-21
WO2013115595A1 (ko) 2013-08-08
PH12014501704A1 (en) 2014-10-13
CN104159884A (zh) 2014-11-19
MX2014009309A (es) 2014-11-10
KR101539761B1 (ko) 2015-07-28
CO7030967A2 (es) 2014-08-21
BR112014018985B1 (pt) 2021-01-19
CN104159884B (zh) 2016-01-13
MX355336B (es) 2018-04-16
PH12014501704B1 (en) 2014-10-13
AU2013215796B2 (en) 2016-09-15
CL2014002029A1 (es) 2014-12-26
MA35906B1 (fr) 2014-12-01
AU2013215796A1 (en) 2014-08-21
PE20142331A1 (es) 2015-01-17
BR112014018985A2 (enExample) 2017-06-20
EA026411B1 (ru) 2017-04-28
MY168411A (en) 2018-11-09

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