ZA201402290B - Cysteamine and/or cystamine for treating ischemic injury - Google Patents
Cysteamine and/or cystamine for treating ischemic injuryInfo
- Publication number
- ZA201402290B ZA201402290B ZA2014/02290A ZA201402290A ZA201402290B ZA 201402290 B ZA201402290 B ZA 201402290B ZA 2014/02290 A ZA2014/02290 A ZA 2014/02290A ZA 201402290 A ZA201402290 A ZA 201402290A ZA 201402290 B ZA201402290 B ZA 201402290B
- Authority
- ZA
- South Africa
- Prior art keywords
- cystamine
- cysteamine
- ischemic injury
- treating ischemic
- treating
- Prior art date
Links
- OOTFVKOQINZBBF-UHFFFAOYSA-N cystamine Chemical compound CCSSCCN OOTFVKOQINZBBF-UHFFFAOYSA-N 0.000 title 1
- 229940099500 cystamine Drugs 0.000 title 1
- UFULAYFCSOUIOV-UHFFFAOYSA-N cysteamine Chemical compound NCCS UFULAYFCSOUIOV-UHFFFAOYSA-N 0.000 title 1
- 208000037906 ischaemic injury Diseases 0.000 title 1
- 229960003151 mercaptamine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161563034P | 2011-11-22 | 2011-11-22 | |
| PCT/US2012/066288 WO2013078335A1 (en) | 2011-11-22 | 2012-11-21 | Cysteamine and/or cystamine for treating ischemic injury |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201402290B true ZA201402290B (en) | 2017-06-28 |
Family
ID=47297472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2014/02290A ZA201402290B (en) | 2011-11-22 | 2014-03-27 | Cysteamine and/or cystamine for treating ischemic injury |
Country Status (16)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR096628A1 (es) * | 2013-06-17 | 2016-01-20 | Raptor Pharmaceuticals Inc | Formulación en perlas de cisteamina de liberación retardada y métodos de preparación y uso de ella |
| KR20180034466A (ko) * | 2015-07-02 | 2018-04-04 | 호리즌 오펀 엘엘씨 | Ado-저항성 시스테아민 유사체 및 그의 용도 |
| CN106591461A (zh) * | 2016-12-29 | 2017-04-26 | 天津协和华美医学诊断技术有限公司 | 一种检测遗传性易栓症相关基因群的检测试剂盒 |
| KR20190119046A (ko) * | 2017-01-19 | 2019-10-21 | 오톨로직 파마슈틱스, 인크. | N-아세틸시스테인의 제제 및 이의 용도 |
| US11357750B2 (en) | 2017-01-25 | 2022-06-14 | Children's Hospital Medical Center | Cysteamine prodrugs |
| WO2021022012A1 (en) * | 2019-07-30 | 2021-02-04 | The Regents Of The University Of California | Methods and composition for treating respiratory obstructive diseases |
| CN113484453B (zh) * | 2021-07-07 | 2022-08-09 | 天津中医药大学 | 一种缺血性脑卒中预警方法 |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2809918A (en) | 1955-10-17 | 1957-10-15 | Victor M Hermelin | Sustained release pharmaceutical preparations |
| DE2010416B2 (de) | 1970-03-05 | 1979-03-29 | Hoechst Ag, 6000 Frankfurt | Oral anwendbare Arzneiform mit Retardwirkung |
| FR2471186A1 (fr) | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation |
| US4301146A (en) | 1980-07-29 | 1981-11-17 | G. D. Searle & Co. | Stabilization of 16-oxygenated prostanoic acid derivatives |
| FR2549051B1 (fr) | 1983-06-22 | 1986-05-16 | Centre Nat Rech Scient | Nouveaux agents radioprotecteurs ayant une structure amino-thioalkyle et procede pour leur preparation |
| FR2573077B1 (fr) * | 1984-11-13 | 1987-02-13 | Sanofi Sa | Nouveaux derives thiosulfonates, leur procede de preparation ainsi que les compositions pharmaceutiques les contenant |
| US4728512A (en) | 1985-05-06 | 1988-03-01 | American Home Products Corporation | Formulations providing three distinct releases |
| US4794001A (en) | 1986-03-04 | 1988-12-27 | American Home Products Corporation | Formulations providing three distinct releases |
| US4916130A (en) * | 1987-09-08 | 1990-04-10 | Green Cross Corporation | Platelet agglutination-inhibiting agent |
| JPH02243619A (ja) * | 1989-03-15 | 1990-09-27 | Green Cross Corp:The | 抗血小板凝集剤 |
| WO1990014087A1 (en) | 1989-05-17 | 1990-11-29 | Pfizer Inc. | 2-piperidino-1-alkanol derivatives as antiischemic agents |
| US5225202A (en) | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
| US5436255A (en) | 1992-07-23 | 1995-07-25 | Pfizer Inc. | Method of treating diseases susceptable to treatment by blocking NMDA-receptors |
| TW281670B (cg-RX-API-DMAC7.html) | 1993-09-02 | 1996-07-21 | Hoffmann La Roche | |
| ZA9610745B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610736B (en) | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
| WO1997023202A1 (en) | 1995-12-22 | 1997-07-03 | STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITYA ND THE UNIVERSITY OF OREGON, EUGENE OREGON | Subtype-selective nmda receptor ligands and the use thereof |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| US6087398A (en) * | 1996-03-01 | 2000-07-11 | South Alabama Medical Science Foundation | Sickle cell anemia treatment |
| FR2753098B1 (fr) * | 1996-09-06 | 1998-11-27 | Sod Conseils Rech Applic | Composition pharmaceutique comprenant au moins un inhibiteur de no synthase et au moins un piegeur des formes reactives de l'oxygene |
| DE19643790A1 (de) | 1996-10-30 | 1998-05-07 | Merck Patent Gmbh | Benzoxazol-Derivat |
| BR9814867A (pt) | 1997-10-24 | 2000-10-03 | Warner Lambert Co | Método para tratar discinesias relacionadas a doenças ou induzidas por drogas |
| PE20000728A1 (es) | 1998-06-26 | 2000-08-21 | Cocensys Inc | Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda |
| WO2000025109A1 (en) | 1998-10-28 | 2000-05-04 | Scofield Dillon F | Electrodynamic particle size analyzer |
| AU1153601A (en) | 1999-10-29 | 2001-05-08 | Merck Sharp & Dohme Limited | Method to treat pain utilizing benzimidazole NMDA NR2B antagonists |
| US6432976B1 (en) | 1999-10-29 | 2002-08-13 | Merck & Co., Inc. | 8-aza-bicyclo[3.2.1]octane NMDA/NR2B antagonists |
| US6489477B1 (en) | 1999-10-29 | 2002-12-03 | Merck & Co., Inc. | 2-aza-bicyclo[2.2.2]octane NMDA/NR2B antigonists |
| US6369076B1 (en) | 1999-10-29 | 2002-04-09 | Merck & Co. Inc. | 5-benzyl-octahydroindole and 6-benzyl-decahydroquinoline NMDA/NR2B antagonists |
| US6316474B1 (en) | 1999-10-29 | 2001-11-13 | Merck & Co., Inc. | 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists |
| US6476041B1 (en) | 1999-10-29 | 2002-11-05 | Merck & Co., Inc. | 1,4 substituted piperidinyl NMDA/NR2B antagonists |
| US6291499B1 (en) | 1999-10-29 | 2001-09-18 | Merck & Co., Inc. | 2-cyclohexyl benzimidazole NMDA/NR2B antagonists |
| ATE515261T1 (de) * | 2003-12-19 | 2011-07-15 | Omega Bio Pharma Ip3 Ltd | Zusammensetzungen zur behandlung von diabetes |
| WO2005107730A2 (en) * | 2004-05-03 | 2005-11-17 | Omega Bio-Pharma (I.P.3) Limited | Cysteamines for treating complications of hypercholesterolemia and diabetes |
| JP5583022B2 (ja) * | 2007-11-30 | 2014-09-03 | ザ レジェンツ オブ ザ ユニヴァースティ オブ カリフォルニア | システアミン生成物を用いる非アルコール性脂肪性肝炎（ｎａｓｈ）の治療方法 |
| RU2428192C1 (ru) * | 2010-06-10 | 2011-09-10 | Войсковая Часть 41598 | Радиозащитное средство |
-
2012
- 2012-11-21 KR KR1020147010492A patent/KR20140097132A/ko not_active Ceased
- 2012-11-21 CN CN201810067673.7A patent/CN108042517A/zh active Pending
- 2012-11-21 SG SG11201402472QA patent/SG11201402472QA/en unknown
- 2012-11-21 US US14/360,095 patent/US20140322315A1/en not_active Abandoned
- 2012-11-21 CN CN201280057439.7A patent/CN103974698A/zh active Pending
- 2012-11-21 EP EP12798116.5A patent/EP2782564B1/en not_active Not-in-force
- 2012-11-21 BR BR112014012167A patent/BR112014012167A2/pt not_active IP Right Cessation
- 2012-11-21 SG SG10201800159QA patent/SG10201800159QA/en unknown
- 2012-11-21 MX MX2014004469A patent/MX2014004469A/es unknown
- 2012-11-21 AU AU2012340670A patent/AU2012340670B2/en not_active Ceased
- 2012-11-21 MY MYPI2014001446A patent/MY165953A/en unknown
- 2012-11-21 WO PCT/US2012/066288 patent/WO2013078335A1/en not_active Ceased
- 2012-11-21 CA CA2851387A patent/CA2851387A1/en not_active Abandoned
- 2012-11-21 JP JP2014542590A patent/JP6411215B2/ja not_active Expired - Fee Related
- 2012-11-21 HK HK15103104.0A patent/HK1202440A1/xx unknown
- 2012-11-21 RU RU2014125282A patent/RU2638807C2/ru not_active IP Right Cessation
-
2014
- 2014-03-27 ZA ZA2014/02290A patent/ZA201402290B/en unknown
- 2014-05-14 IL IL232608A patent/IL232608A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2014125282A (ru) | 2015-12-27 |
| IL232608A0 (en) | 2014-06-30 |
| EP2782564B1 (en) | 2019-01-09 |
| CN108042517A (zh) | 2018-05-18 |
| US20140322315A1 (en) | 2014-10-30 |
| CN103974698A (zh) | 2014-08-06 |
| MY165953A (en) | 2018-05-18 |
| JP6411215B2 (ja) | 2018-10-24 |
| SG11201402472QA (en) | 2014-06-27 |
| MX2014004469A (es) | 2014-08-01 |
| JP2014533701A (ja) | 2014-12-15 |
| RU2638807C2 (ru) | 2017-12-15 |
| SG10201800159QA (en) | 2018-02-27 |
| WO2013078335A1 (en) | 2013-05-30 |
| BR112014012167A2 (pt) | 2017-05-30 |
| AU2012340670A1 (en) | 2014-04-17 |
| AU2012340670B2 (en) | 2016-12-22 |
| KR20140097132A (ko) | 2014-08-06 |
| CA2851387A1 (en) | 2013-05-30 |
| HK1202440A1 (zh) | 2015-10-02 |
| EP2782564A1 (en) | 2014-10-01 |
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