ZA201202610B - Il-1 binding proteins - Google Patents
Il-1 binding proteinsInfo
- Publication number
- ZA201202610B ZA201202610B ZA2012/02610A ZA201202610A ZA201202610B ZA 201202610 B ZA201202610 B ZA 201202610B ZA 2012/02610 A ZA2012/02610 A ZA 2012/02610A ZA 201202610 A ZA201202610 A ZA 201202610A ZA 201202610 B ZA201202610 B ZA 201202610B
- Authority
- ZA
- South Africa
- Prior art keywords
- binding proteins
- proteins
- binding
- Prior art date
Links
- 102000014914 Carrier Proteins Human genes 0.000 title 1
- 108091008324 binding proteins Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
- G01N2333/545—IL-1
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
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- Pulmonology (AREA)
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- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (2)
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| US25185609P | 2009-10-15 | 2009-10-15 | |
| PCT/US2010/052849 WO2011047266A1 (en) | 2009-10-15 | 2010-10-15 | Il-1 binding proteins |
Publications (1)
| Publication Number | Publication Date |
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| ZA201202610B true ZA201202610B (en) | 2012-12-27 |
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Family Applications (1)
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| ZA2012/02610A ZA201202610B (en) | 2009-10-15 | 2012-04-11 | Il-1 binding proteins |
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|---|---|
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| EP (1) | EP2488201A4 (enExample) |
| JP (1) | JP2013507929A (enExample) |
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| AU (1) | AU2010306681A1 (enExample) |
| BR (1) | BR112012007365A2 (enExample) |
| CA (1) | CA2775402A1 (enExample) |
| IL (1) | IL219202A0 (enExample) |
| IN (1) | IN2012DN02634A (enExample) |
| MX (1) | MX2012004412A (enExample) |
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| WO (1) | WO2011047266A1 (enExample) |
| ZA (1) | ZA201202610B (enExample) |
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| CN102112154B (zh) | 2008-05-30 | 2013-10-30 | 埃克斯生物科技公司 | 白细胞介素-1α抗体及使用方法 |
| NZ589436A (en) | 2008-06-03 | 2012-12-21 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| RU2010153580A (ru) | 2008-06-03 | 2012-07-20 | Эбботт Лэборетриз (Us) | Иммуноглобулины с двумя вариабельными доменами и их применение |
| RU2011104348A (ru) * | 2008-07-08 | 2012-08-20 | Эбботт Лэборетриз (Us) | Иммуноглобулины с двойным вариабельным доменом против простагландина е2 и их применение |
| TW201119673A (en) * | 2009-09-01 | 2011-06-16 | Abbott Lab | Dual variable domain immunoglobulins and uses thereof |
| JP2013507928A (ja) * | 2009-10-15 | 2013-03-07 | アボット・ラボラトリーズ | 二重可変ドメイン免疫グロブリンおよびその使用 |
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| MX341578B (es) | 2011-02-08 | 2016-08-25 | Abbvie Inc | Tratamiento de la osteoartritis y del dolor. |
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| US20140213459A1 (en) * | 2011-05-27 | 2014-07-31 | Roland Beckmann | Antibodies with improved folding stability |
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| TW201623331A (zh) * | 2014-03-12 | 2016-07-01 | 普羅帝納生物科學公司 | 抗黑色素瘤細胞黏著分子(mcam)抗體類及使用彼等之相關方法 |
| WO2015168474A1 (en) * | 2014-04-30 | 2015-11-05 | President And Fellows Of Harvard College | Fusion proteins for treating cancer and related methods |
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| SG11201703767XA (en) | 2014-11-10 | 2017-06-29 | Genentech Inc | Anti-interleukin-33 antibodies and uses thereof |
| AU2015345320A1 (en) * | 2014-11-10 | 2017-04-06 | F. Hoffmann-La Roche Ag | Anti-IL-1beta antibodies and methods of use |
| CN107109494B (zh) | 2014-11-10 | 2023-10-27 | 豪夫迈·罗氏有限公司 | Il-33介导型疾病的治疗方法和诊断方法 |
| US10093733B2 (en) | 2014-12-11 | 2018-10-09 | Abbvie Inc. | LRP-8 binding dual variable domain immunoglobulin proteins |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US20180291097A1 (en) * | 2015-06-04 | 2018-10-11 | Craig Basson | Use of il-1 beta binding antibodies to treat peripheral arterial disease |
| TW201710286A (zh) | 2015-06-15 | 2017-03-16 | 艾伯維有限公司 | 抗vegf、pdgf及/或其受體之結合蛋白 |
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| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
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| MA47130B1 (fr) * | 2016-12-21 | 2025-05-30 | Cephalon, Inc. | Anticorps se liant spécifiquement à l'il-15 humaine et leurs utilisations |
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| CN110818793A (zh) * | 2018-08-14 | 2020-02-21 | 中山康方生物医药有限公司 | 抗IL-1β的抗体、其药物组合物及其用途 |
| CN113227137A (zh) * | 2018-12-21 | 2021-08-06 | 诺华股份有限公司 | IL-1β抗体在骨髓增生异常综合征的治疗或预防中的用途 |
| KR102503349B1 (ko) | 2019-05-14 | 2023-02-23 | 프로벤션 바이오, 인코포레이티드 | 제1형 당뇨병을 예방하기 위한 방법 및 조성물 |
| KR102087743B1 (ko) * | 2019-06-10 | 2020-03-12 | 을지대학교 산학협력단 | IL-1beta에 특이적으로 결합하는 항체 및 그의 용도 |
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| CN113651888B (zh) * | 2020-08-13 | 2022-08-16 | 广东东阳光药业有限公司 | Il-11的抗体及其应用 |
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| WO1995001997A1 (en) * | 1993-07-09 | 1995-01-19 | Smithkline Beecham Corporation | RECOMBINANT AND HUMANIZED IL-1β ANTIBODIES FOR TREATMENT OF IL-1 MEDIATED INFLAMMATORY DISORDERS IN MAN |
| JP4955185B2 (ja) * | 2000-06-29 | 2012-06-20 | アボット・ラボラトリーズ | 二重特異性抗体ならびに作製方法および使用方法 |
| US20030026806A1 (en) * | 2000-10-27 | 2003-02-06 | Amgen Inc. | Antibodies and other selective IL-1 binding agents that allow binding to IL-1 receptor but not activation thereof |
| WO2003073982A2 (en) * | 2002-02-28 | 2003-09-12 | Eli Lilly And Company | Anti-interleukin-1 beta analogs |
| WO2004067568A2 (en) * | 2003-01-24 | 2004-08-12 | Applied Molecular Evolution, Inc | Human il-1 beta antagonists |
| GB0303337D0 (en) * | 2003-02-13 | 2003-03-19 | Celltech R&D Ltd | Biological products |
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| EP2314623B1 (en) * | 2005-06-21 | 2012-07-04 | XOMA Technology Ltd. | IL-1beta binding antibodies and fragments thereof |
| US7612181B2 (en) * | 2005-08-19 | 2009-11-03 | Abbott Laboratories | Dual variable domain immunoglobulin and uses thereof |
| US20090215992A1 (en) * | 2005-08-19 | 2009-08-27 | Chengbin Wu | Dual variable domain immunoglobulin and uses thereof |
| AU2006306280B2 (en) * | 2005-10-26 | 2010-06-17 | Novartis Ag | Novel use of IL-1beta compounds |
| DK2097455T3 (en) | 2006-11-02 | 2014-12-15 | Genentech Inc | HUMANIZED ANTI-FACTOR D ANTIBODIES |
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| KR20110110349A (ko) * | 2009-01-29 | 2011-10-06 | 아보트 러보러터리즈 | Il-1 결합 단백질 |
| US20110016506A1 (en) * | 2009-07-15 | 2011-01-20 | Yung-Yu Lu | Set-Top Box |
| NZ628792A (en) * | 2010-05-14 | 2016-03-31 | Abbvie Inc | Il-1 binding proteins |
-
2010
- 2010-10-15 MX MX2012004412A patent/MX2012004412A/es not_active Application Discontinuation
- 2010-10-15 CA CA2775402A patent/CA2775402A1/en not_active Abandoned
- 2010-10-15 WO PCT/US2010/052849 patent/WO2011047266A1/en not_active Ceased
- 2010-10-15 EP EP10824167.0A patent/EP2488201A4/en not_active Withdrawn
- 2010-10-15 US US12/905,499 patent/US8398966B2/en active Active
- 2010-10-15 KR KR1020127012405A patent/KR20120104542A/ko not_active Withdrawn
- 2010-10-15 CN CN2010800563660A patent/CN102655880A/zh active Pending
- 2010-10-15 JP JP2012534395A patent/JP2013507929A/ja not_active Withdrawn
- 2010-10-15 IN IN2634DEN2012 patent/IN2012DN02634A/en unknown
- 2010-10-15 RU RU2012119788/10A patent/RU2012119788A/ru not_active Application Discontinuation
- 2010-10-15 AU AU2010306681A patent/AU2010306681A1/en not_active Abandoned
- 2010-10-15 UY UY0001032949A patent/UY32949A/es not_active Application Discontinuation
- 2010-10-15 AR ARP100103772A patent/AR078650A1/es unknown
- 2010-10-15 BR BR112012007365A patent/BR112012007365A2/pt not_active IP Right Cessation
- 2010-10-15 TW TW099135501A patent/TW201124427A/zh unknown
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2012
- 2012-04-11 ZA ZA2012/02610A patent/ZA201202610B/en unknown
- 2012-04-15 IL IL219202A patent/IL219202A0/en unknown
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2013
- 2013-02-25 US US13/775,540 patent/US20130295004A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AR078650A1 (es) | 2011-11-23 |
| IN2012DN02634A (enExample) | 2015-09-04 |
| UY32949A (es) | 2011-02-28 |
| EP2488201A4 (en) | 2013-12-25 |
| US20110142761A1 (en) | 2011-06-16 |
| CN102655880A (zh) | 2012-09-05 |
| CA2775402A1 (en) | 2011-04-21 |
| US8398966B2 (en) | 2013-03-19 |
| IL219202A0 (en) | 2012-06-28 |
| WO2011047266A1 (en) | 2011-04-21 |
| BR112012007365A2 (pt) | 2016-11-22 |
| EP2488201A1 (en) | 2012-08-22 |
| AU2010306681A1 (en) | 2012-04-19 |
| JP2013507929A (ja) | 2013-03-07 |
| RU2012119788A (ru) | 2013-11-20 |
| MX2012004412A (es) | 2012-05-08 |
| TW201124427A (en) | 2011-07-16 |
| US20130295004A1 (en) | 2013-11-07 |
| KR20120104542A (ko) | 2012-09-21 |
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