ZA201005959B - 4-(pyrrolo[2,3-c]pyridine-3-yl)-pyrimidine-2-amine derivatives - Google Patents
4-(pyrrolo[2,3-c]pyridine-3-yl)-pyrimidine-2-amine derivativesInfo
- Publication number
- ZA201005959B ZA201005959B ZA2010/05959A ZA201005959A ZA201005959B ZA 201005959 B ZA201005959 B ZA 201005959B ZA 2010/05959 A ZA2010/05959 A ZA 2010/05959A ZA 201005959 A ZA201005959 A ZA 201005959A ZA 201005959 B ZA201005959 B ZA 201005959B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrrolo
- pyrimidine
- pyridine
- amine derivatives
- amine
- Prior art date
Links
- ULPADEPZZAIIOV-UHFFFAOYSA-N 4-(1h-pyrrolo[2,3-c]pyridin-3-yl)pyrimidin-2-amine Chemical class NC1=NC=CC(C=2C3=CC=NC=C3NC=2)=N1 ULPADEPZZAIIOV-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008005493A DE102008005493A1 (de) | 2008-01-22 | 2008-01-22 | 4-(Pyrrolo[2,3-c] pyridine-3-yl)-pyrimidin-2-yl-amin-derivate |
| PCT/EP2008/011098 WO2009092431A1 (de) | 2008-01-22 | 2008-12-23 | 4-(pyrrolo[2,3-c]pyridine-3-yl)-pyrimidin-2-amin-derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201005959B true ZA201005959B (en) | 2011-04-28 |
Family
ID=40386204
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/05959A ZA201005959B (en) | 2008-01-22 | 2010-08-20 | 4-(pyrrolo[2,3-c]pyridine-3-yl)-pyrimidine-2-amine derivatives |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20100292262A1 (OSRAM) |
| EP (1) | EP2231664A1 (OSRAM) |
| JP (1) | JP5524864B2 (OSRAM) |
| KR (1) | KR20100112626A (OSRAM) |
| CN (1) | CN101918404A (OSRAM) |
| AR (1) | AR070212A1 (OSRAM) |
| AU (1) | AU2008348816B2 (OSRAM) |
| BR (1) | BRPI0821936A2 (OSRAM) |
| CA (1) | CA2712612A1 (OSRAM) |
| DE (1) | DE102008005493A1 (OSRAM) |
| IL (1) | IL206905A0 (OSRAM) |
| MX (1) | MX2010007927A (OSRAM) |
| WO (1) | WO2009092431A1 (OSRAM) |
| ZA (1) | ZA201005959B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101723936B (zh) * | 2008-10-27 | 2014-01-15 | 上海睿星基因技术有限公司 | 激酶抑制剂及其在药学中的用途 |
| JP2014515368A (ja) | 2011-05-26 | 2014-06-30 | 第一三共株式会社 | プロテインキナーゼ阻害剤としての複素環化合物 |
| DK2922828T3 (da) | 2012-11-21 | 2020-08-31 | Ptc Therapeutics Inc | 4,6-diamino-pyrimidin-derivater som bmi-1-inhibitorer til at behandle cancer |
| TWI663166B (zh) | 2013-04-24 | 2019-06-21 | 健生藥品公司 | 新化合物 |
| CA2922657C (en) * | 2013-08-30 | 2022-04-12 | Ptc Therapeutics, Inc. | Substituted pyrimidine bmi-1 inhibitors |
| TWI704146B (zh) | 2013-09-26 | 2020-09-11 | 比利時商健生藥品公司 | 用作ＮＩＫ抑制劑之新的1-(４-嘧啶基)-１Ｈ-吡唑並[３,２-ｃ]吡啶衍生物 |
| TWI627173B (zh) | 2013-09-26 | 2018-06-21 | 比利時商健生藥品公司 | 作為ＮＩＫ抑制劑的新穎３－（１Ｈ－吡唑－４－基）－１Ｈ－吡咯并［２，３－ｃ］吡啶衍生物 |
| US10584115B2 (en) | 2013-11-21 | 2020-03-10 | Ptc Therapeutics, Inc. | Substituted pyridine and pyrazine BMI-1 inhibitors |
| CN107074882B (zh) | 2014-10-23 | 2019-07-30 | 詹森药业有限公司 | 作为nik抑制剂的新的吡唑并嘧啶衍生物 |
| KR102500071B1 (ko) | 2014-10-23 | 2023-02-14 | 얀센 파마슈티카 엔.브이. | Ｎｉｋ 억제제로서의 신규 화합물 |
| ES2704749T3 (es) | 2014-10-23 | 2019-03-19 | Janssen Pharmaceutica Nv | Nuevos derivados de pirazol en calidad de inhibidores de nik |
| EA033238B1 (ru) | 2014-10-23 | 2019-09-30 | Янссен Фармацевтика Нв | Новые производные тиенопиримидина в качестве ингибиторов nik |
| BR112021002630A2 (pt) | 2018-08-17 | 2021-05-11 | Ptc Therapeutics, Inc. | método para tratar câncer pancreático |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5747469A (en) | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
| GB9904387D0 (en) | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
| GB0308466D0 (en) | 2003-04-11 | 2003-05-21 | Novartis Ag | Organic compounds |
| WO2005123672A2 (en) * | 2004-06-14 | 2005-12-29 | Takeda San Diego, Inc. | Kinase inhibitors |
| WO2006050076A1 (en) | 2004-10-29 | 2006-05-11 | Janssen Pharmaceutica, N.V. | Pyrimidinyl substituted fused-pyrrolyl compounds useful in treating kinase disorders |
| KR20080063809A (ko) * | 2005-09-30 | 2008-07-07 | 버텍스 파마슈티칼스 인코포레이티드 | 야누스 키나아제의 억제제로서 유용한 데아자퓨린 |
| DE102006012617A1 (de) * | 2006-03-20 | 2007-09-27 | Merck Patent Gmbh | 4-(Pyrrolopyridinyl)-pyrimidinyl-2-amin-derivate |
-
2008
- 2008-01-22 DE DE102008005493A patent/DE102008005493A1/de not_active Withdrawn
- 2008-12-23 AU AU2008348816A patent/AU2008348816B2/en not_active Ceased
- 2008-12-23 JP JP2010543386A patent/JP5524864B2/ja not_active Expired - Fee Related
- 2008-12-23 KR KR1020107018575A patent/KR20100112626A/ko not_active Withdrawn
- 2008-12-23 WO PCT/EP2008/011098 patent/WO2009092431A1/de not_active Ceased
- 2008-12-23 US US12/863,817 patent/US20100292262A1/en not_active Abandoned
- 2008-12-23 CA CA2712612A patent/CA2712612A1/en not_active Abandoned
- 2008-12-23 CN CN200880125171XA patent/CN101918404A/zh active Pending
- 2008-12-23 MX MX2010007927A patent/MX2010007927A/es not_active Application Discontinuation
- 2008-12-23 BR BRPI0821936-2A patent/BRPI0821936A2/pt not_active IP Right Cessation
- 2008-12-23 EP EP08871371A patent/EP2231664A1/de not_active Withdrawn
-
2009
- 2009-01-21 AR ARP090100174A patent/AR070212A1/es unknown
-
2010
- 2010-07-08 IL IL206905A patent/IL206905A0/en unknown
- 2010-08-20 ZA ZA2010/05959A patent/ZA201005959B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP5524864B2 (ja) | 2014-06-18 |
| AR070212A1 (es) | 2010-03-25 |
| IL206905A0 (en) | 2010-12-30 |
| JP2011510028A (ja) | 2011-03-31 |
| WO2009092431A1 (de) | 2009-07-30 |
| EP2231664A1 (de) | 2010-09-29 |
| CA2712612A1 (en) | 2009-07-30 |
| KR20100112626A (ko) | 2010-10-19 |
| DE102008005493A8 (de) | 2010-03-25 |
| AU2008348816A1 (en) | 2009-07-30 |
| AU2008348816B2 (en) | 2011-10-20 |
| BRPI0821936A2 (pt) | 2015-06-16 |
| DE102008005493A1 (de) | 2009-07-23 |
| CN101918404A (zh) | 2010-12-15 |
| MX2010007927A (es) | 2010-08-09 |
| US20100292262A1 (en) | 2010-11-18 |
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