ZA200908303B - A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation - Google Patents
A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregationInfo
- Publication number
- ZA200908303B ZA200908303B ZA2009/08303A ZA200908303A ZA200908303B ZA 200908303 B ZA200908303 B ZA 200908303B ZA 2009/08303 A ZA2009/08303 A ZA 2009/08303A ZA 200908303 A ZA200908303 A ZA 200908303A ZA 200908303 B ZA200908303 B ZA 200908303B
- Authority
- ZA
- South Africa
- Prior art keywords
- disorders
- treatment
- protein aggregation
- cyclohexane polyalcohol
- polyalcohol formulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US78052606P | 2006-03-09 | 2006-03-09 | |
| US81986406P | 2006-07-11 | 2006-07-11 | |
| US89766707P | 2007-01-26 | 2007-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200908303B true ZA200908303B (en) | 2012-08-29 |
Family
ID=38474578
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2009/08303A ZA200908303B (en) | 2006-03-09 | 2009-11-24 | A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20100113613A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1996175A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009529502A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20090026247A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103054837A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007222864A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0708725A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2644804A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA200801967A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL193970A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2008011553A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ571181A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007101353A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200908303B (cg-RX-API-DMAC7.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| WO2008034244A1 (en) * | 2006-09-21 | 2008-03-27 | Waratah Pharmaceuticals Inc. | The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases |
| CA2670405A1 (en) * | 2006-11-24 | 2008-05-29 | Waratah Pharmaceuticals Inc. | Combination treatments for alzheimer's disease and related neurodegenerative diseases |
| DE102007030695A1 (de) * | 2007-07-01 | 2009-01-08 | Sciconcept Gmbh | Co-Kristalle aus Harnstoff mit Amid- und/oder Harnstoffderivaten |
| US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| WO2012173808A1 (en) * | 2011-06-03 | 2012-12-20 | Elan Pharmaceuticals, Inc. | Scyllo-inositol for the treatment of behavioral and psychiatric disorders |
| US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
| JP6499077B2 (ja) | 2012-10-25 | 2019-04-10 | ザ ジェネラル ホスピタル コーポレイション | アルツハイマー病と関連疾患の治療のための併用療法 |
| US20160129084A1 (en) * | 2013-03-06 | 2016-05-12 | Acorda Therapeutics, Inc. | Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure |
| US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
| US10188757B2 (en) | 2013-10-22 | 2019-01-29 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
| JP2019524865A (ja) | 2016-08-31 | 2019-09-05 | ザ ジェネラル ホスピタル コーポレイション | 神経変性疾患と関連する神経炎症におけるマクロファージ/ミクログリア |
| JP7202376B2 (ja) | 2017-07-20 | 2023-01-11 | エーゼットセラピーズ, インコーポレイテッド | クロモリンナトリウムおよびイブプロフェンの粉末製剤 |
| JP2021529771A (ja) | 2018-07-02 | 2021-11-04 | ザ ジェネラル ホスピタル コーポレイション | クロモリンナトリウムおよびα−ラクトースの粉末製剤 |
| WO2020074944A1 (en) | 2018-10-11 | 2020-04-16 | Sanifit Therapeutics S.A. | Inositol phosphates for the treatment of ectopic calcification |
| MX2021006869A (es) | 2018-12-10 | 2021-07-02 | Massachusetts Gen Hospital | Esteres de cromolin y usos de los mismos. |
| EP4132507A4 (en) | 2020-04-06 | 2024-05-15 | The General Hospital Corporation | METHODS FOR TREATING CORONAVIRUS-INDUCED INFLAMMATORY CONDITIONS |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4454151A (en) * | 1982-03-22 | 1984-06-12 | Syntex (U.S.A.) Inc. | Use of pyrrolo pyrroles in treatment of ophthalmic diseases |
| US4515722A (en) * | 1982-03-30 | 1985-05-07 | Merck & Co., Inc. | Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents |
| US4474806A (en) * | 1982-05-10 | 1984-10-02 | Merck & Co., Inc. | Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents |
| US4952396A (en) * | 1986-11-19 | 1990-08-28 | Linus Pauling Institute Of Science & Medicine | Method of using phytic acid for inhibiting tumor growth |
| US4847082A (en) * | 1987-01-21 | 1989-07-11 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
| US4758430A (en) * | 1987-01-21 | 1988-07-19 | Robert Sabin | Method of treatment of Alzheimer's disease using phytic acid |
| SE8904355D0 (sv) * | 1989-12-21 | 1989-12-21 | Perstorp Ab | Medicament |
| US5217959A (en) * | 1990-09-06 | 1993-06-08 | Robert Sabin | Method of treating multiple sclerosis with phytic acid |
| US5112814A (en) * | 1990-10-24 | 1992-05-12 | Robert Sabin | Method of treatment of Parkinson's disease using phytic acid |
| KR0185215B1 (ko) * | 1990-11-30 | 1999-05-01 | 요시다 쇼오지 | 서방성 안구삽입용 약제 |
| SE9102068L (sv) * | 1991-07-03 | 1993-01-04 | Perstorp Ab | Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav |
| SE469260B (sv) * | 1992-02-25 | 1993-06-14 | Perstorp Ab | En farmaceutisk komposition med foerbaettrad biotillgaenglighet avseende inositolfosfat |
| NZ314111A (en) * | 1992-10-05 | 1997-08-22 | Virginia Tech Intell Prop | Preparation of d-chiro-inositol by reducing d-chiro-3-inosose |
| US5643562A (en) * | 1993-03-29 | 1997-07-01 | Queen's University Of Kingston | Method for treating amyloidosis |
| US5972328A (en) * | 1993-03-29 | 1999-10-26 | Queen's University At Kingston | Method for treating amyloidosis |
| US5840294A (en) * | 1993-03-29 | 1998-11-24 | Queen's University At Kingston | Method for treating amyloidosis |
| DK0619369T3 (da) * | 1993-04-05 | 2003-10-06 | Aveve Nv | Phytathydrolyse og enzymsammensætning til hydrolyse af phytat |
| ES2130440T3 (es) * | 1993-08-11 | 1999-07-01 | Hokko Chem Ind Co | Proceso para producir d-(quiro)-inositol. |
| SE502574C2 (sv) * | 1994-01-25 | 1995-11-13 | Perstorp Ab | En farmaceutisk komposition med förbättrad biotillgänglighet hos inositolfosfat |
| US5858326A (en) * | 1995-06-06 | 1999-01-12 | Neurochem, Inc. | Methods of increasing amyloid deposition |
| US5756541A (en) * | 1996-03-11 | 1998-05-26 | Qlt Phototherapeutics Inc | Vision through photodynamic therapy of the eye |
| US6232486B1 (en) * | 1996-06-11 | 2001-05-15 | Nutrimed Biotech | Molecular probes and modulators for PI-PLC and PI 3-kinase |
| US5880099A (en) * | 1996-09-20 | 1999-03-09 | The Regents Of The University Of California | Inositol polyphosphates and methods of using same |
| US5977078A (en) * | 1996-09-20 | 1999-11-02 | The Regents Of The Univesity Of California | Inositol polyphosphate derivatives and methods of using same |
| US5998485A (en) * | 1997-06-16 | 1999-12-07 | Cedars-Sinai Medical Center | Method for modulating immune response with inositol |
| US6153603A (en) * | 1997-06-27 | 2000-11-28 | Perstorp Ab | Method of treating angiogenesis in tumor tissue |
| US6310073B1 (en) * | 1998-07-28 | 2001-10-30 | Queen's University At Kingston | Methods and compositions to treat glycosaminoglycan-associated molecular interactions |
| US6818430B1 (en) * | 1999-06-07 | 2004-11-16 | Hokko Chemical Industry Co., Ltd. | Process for producing L-epi-2-inosose and novel process for producing epi-inositol |
| US6329256B1 (en) * | 1999-09-24 | 2001-12-11 | Advanced Micro Devices, Inc. | Self-aligned damascene gate formation with low gate resistance |
| NZ518685A (en) * | 1999-10-18 | 2004-04-30 | Muscletech Res And Dev Inc | Whey protein derivatives as food supplements that increase nitric oxide production in the body to enhance muscle size and strength |
| US6331313B1 (en) * | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| DE10031955A1 (de) * | 2000-06-30 | 2002-01-17 | Deutsches Krebsforsch | Curcumin-Derivate mit gegenüber Curcumin verbesserter Wasserlöslichkeit und diese enthaltende Arzneimittel |
| AU2002236988A1 (en) * | 2001-02-06 | 2002-08-19 | Novartis Ag | Photodynamic therapy of occult choroidal neovascularization linked to age-related macular degeneration |
| CA2437561A1 (en) * | 2001-02-06 | 2002-08-15 | Qlt Inc. | Use of additional photodynamic therapy in the treatment of choroidal neovasculature |
| US20030181531A1 (en) * | 2003-02-11 | 2003-09-25 | David Sherris | Compositions and methods of administering tubulin binding agents for the treatment of ocular diseases |
| WO2003007944A1 (en) * | 2001-07-20 | 2003-01-30 | Qlt, Inc. | Treatment of macular edema with photodynamic therapy |
| US20040058313A1 (en) * | 2002-04-24 | 2004-03-25 | Abreu Marcio Marc | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
| US7521481B2 (en) * | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| ATE458042T1 (de) * | 2003-10-14 | 2010-03-15 | Hokko Chem Ind Co | Verfahren zur herstellung von scyllo-inositol |
| EP2186518A1 (en) * | 2004-11-17 | 2010-05-19 | McLaurin, Joanne | Composition and methods for treatment of disorders of protein aggregation |
-
2007
- 2007-03-09 JP JP2008557568A patent/JP2009529502A/ja active Pending
- 2007-03-09 CA CA002644804A patent/CA2644804A1/en not_active Abandoned
- 2007-03-09 EA EA200801967A patent/EA200801967A1/ru unknown
- 2007-03-09 CN CN201210257027XA patent/CN103054837A/zh active Pending
- 2007-03-09 BR BRPI0708725-0A patent/BRPI0708725A2/pt not_active IP Right Cessation
- 2007-03-09 AU AU2007222864A patent/AU2007222864A1/en not_active Abandoned
- 2007-03-09 EP EP07710726A patent/EP1996175A4/en not_active Withdrawn
- 2007-03-09 NZ NZ571181A patent/NZ571181A/en not_active IP Right Cessation
- 2007-03-09 US US12/282,030 patent/US20100113613A1/en not_active Abandoned
- 2007-03-09 WO PCT/CA2007/000395 patent/WO2007101353A1/en not_active Ceased
- 2007-03-09 MX MX2008011553A patent/MX2008011553A/es not_active Application Discontinuation
- 2007-03-09 KR KR1020087024122A patent/KR20090026247A/ko not_active Ceased
-
2008
- 2008-09-08 IL IL193970A patent/IL193970A0/en unknown
-
2009
- 2009-11-24 ZA ZA2009/08303A patent/ZA200908303B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2007222864A1 (en) | 2007-09-13 |
| IL193970A0 (en) | 2009-08-03 |
| CN103054837A (zh) | 2013-04-24 |
| EA200801967A1 (ru) | 2009-04-28 |
| AU2007222864A8 (en) | 2010-06-10 |
| WO2007101353A1 (en) | 2007-09-13 |
| CA2644804A1 (en) | 2007-09-13 |
| BRPI0708725A2 (pt) | 2011-06-07 |
| EP1996175A1 (en) | 2008-12-03 |
| EP1996175A4 (en) | 2009-06-10 |
| US20100113613A1 (en) | 2010-05-06 |
| MX2008011553A (es) | 2008-12-09 |
| JP2009529502A (ja) | 2009-08-20 |
| NZ571181A (en) | 2011-12-22 |
| KR20090026247A (ko) | 2009-03-12 |
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