CA2644804A1 - A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation - Google Patents

A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation Download PDF

Info

Publication number
CA2644804A1
CA2644804A1 CA002644804A CA2644804A CA2644804A1 CA 2644804 A1 CA2644804 A1 CA 2644804A1 CA 002644804 A CA002644804 A CA 002644804A CA 2644804 A CA2644804 A CA 2644804A CA 2644804 A1 CA2644804 A1 CA 2644804A1
Authority
CA
Canada
Prior art keywords
compound
dosage form
cyclohexane polyalcohol
alkyl
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002644804A
Other languages
English (en)
French (fr)
Inventor
Antonio Cruz
Joanne Mclaurin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waratah Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2644804A1 publication Critical patent/CA2644804A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002644804A 2006-03-09 2007-03-09 A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation Abandoned CA2644804A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US78052606P 2006-03-09 2006-03-09
US60/780,526 2006-03-09
US81986406P 2006-07-11 2006-07-11
US60/819,864 2006-07-11
US89766707P 2007-01-26 2007-01-26
US60/897,667 2007-01-26
PCT/CA2007/000395 WO2007101353A1 (en) 2006-03-09 2007-03-09 A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation

Publications (1)

Publication Number Publication Date
CA2644804A1 true CA2644804A1 (en) 2007-09-13

Family

ID=38474578

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002644804A Abandoned CA2644804A1 (en) 2006-03-09 2007-03-09 A cyclohexane polyalcohol formulation for treatment of disorders of protein aggregation

Country Status (14)

Country Link
US (1) US20100113613A1 (cg-RX-API-DMAC7.html)
EP (1) EP1996175A4 (cg-RX-API-DMAC7.html)
JP (1) JP2009529502A (cg-RX-API-DMAC7.html)
KR (1) KR20090026247A (cg-RX-API-DMAC7.html)
CN (1) CN103054837A (cg-RX-API-DMAC7.html)
AU (1) AU2007222864A1 (cg-RX-API-DMAC7.html)
BR (1) BRPI0708725A2 (cg-RX-API-DMAC7.html)
CA (1) CA2644804A1 (cg-RX-API-DMAC7.html)
EA (1) EA200801967A1 (cg-RX-API-DMAC7.html)
IL (1) IL193970A0 (cg-RX-API-DMAC7.html)
MX (1) MX2008011553A (cg-RX-API-DMAC7.html)
NZ (1) NZ571181A (cg-RX-API-DMAC7.html)
WO (1) WO2007101353A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200908303B (cg-RX-API-DMAC7.html)

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US7521481B2 (en) 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
WO2008034244A1 (en) * 2006-09-21 2008-03-27 Waratah Pharmaceuticals Inc. The combination of a cyclohexanehexol and a nsaid for the treatment of neurodegenerative diseases
CA2670405A1 (en) * 2006-11-24 2008-05-29 Waratah Pharmaceuticals Inc. Combination treatments for alzheimer's disease and related neurodegenerative diseases
DE102007030695A1 (de) * 2007-07-01 2009-01-08 Sciconcept Gmbh Co-Kristalle aus Harnstoff mit Amid- und/oder Harnstoffderivaten
US9925282B2 (en) 2009-01-29 2018-03-27 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
WO2012173808A1 (en) * 2011-06-03 2012-12-20 Elan Pharmaceuticals, Inc. Scyllo-inositol for the treatment of behavioral and psychiatric disorders
US10058530B2 (en) 2012-10-25 2018-08-28 The General Hospital Corporation Combination therapies for the treatment of Alzheimer's disease and related disorders
JP6499077B2 (ja) 2012-10-25 2019-04-10 ザ ジェネラル ホスピタル コーポレイション アルツハイマー病と関連疾患の治療のための併用療法
US20160129084A1 (en) * 2013-03-06 2016-05-12 Acorda Therapeutics, Inc. Therapeutic Dosing of a Neuregulin or a Fragment Thereof for Treatment or Prophylaxis of Heart Failure
US10525005B2 (en) 2013-05-23 2020-01-07 The General Hospital Corporation Cromolyn compositions and methods thereof
US10188757B2 (en) 2013-10-22 2019-01-29 The General Hospital Corporation Cromolyn derivatives and related methods of imaging and treatment
JP2019524865A (ja) 2016-08-31 2019-09-05 ザ ジェネラル ホスピタル コーポレイション 神経変性疾患と関連する神経炎症におけるマクロファージ／ミクログリア
JP7202376B2 (ja) 2017-07-20 2023-01-11 エーゼットセラピーズ， インコーポレイテッド クロモリンナトリウムおよびイブプロフェンの粉末製剤
JP2021529771A (ja) 2018-07-02 2021-11-04 ザ ジェネラル ホスピタル コーポレイション クロモリンナトリウムおよびα−ラクトースの粉末製剤
WO2020074944A1 (en) 2018-10-11 2020-04-16 Sanifit Therapeutics S.A. Inositol phosphates for the treatment of ectopic calcification
MX2021006869A (es) 2018-12-10 2021-07-02 Massachusetts Gen Hospital Esteres de cromolin y usos de los mismos.
EP4132507A4 (en) 2020-04-06 2024-05-15 The General Hospital Corporation METHODS FOR TREATING CORONAVIRUS-INDUCED INFLAMMATORY CONDITIONS

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US4515722A (en) * 1982-03-30 1985-05-07 Merck & Co., Inc. Phosphatidyl inositol analogs useful as anti-inflammatory/analgesic agents
US4474806A (en) * 1982-05-10 1984-10-02 Merck & Co., Inc. Sulfonyl or carbonyl inositol derivatives useful as anti-inflammatory/analgesic agents
US4952396A (en) * 1986-11-19 1990-08-28 Linus Pauling Institute Of Science & Medicine Method of using phytic acid for inhibiting tumor growth
US4847082A (en) * 1987-01-21 1989-07-11 Robert Sabin Method of treatment of Alzheimer's disease using phytic acid
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US5217959A (en) * 1990-09-06 1993-06-08 Robert Sabin Method of treating multiple sclerosis with phytic acid
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KR0185215B1 (ko) * 1990-11-30 1999-05-01 요시다 쇼오지 서방성 안구삽입용 약제
SE9102068L (sv) * 1991-07-03 1993-01-04 Perstorp Ab Derivat av inositol, kompositioner innehaallande dessa samt anvaendning daerav
SE469260B (sv) * 1992-02-25 1993-06-14 Perstorp Ab En farmaceutisk komposition med foerbaettrad biotillgaenglighet avseende inositolfosfat
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US5840294A (en) * 1993-03-29 1998-11-24 Queen's University At Kingston Method for treating amyloidosis
DK0619369T3 (da) * 1993-04-05 2003-10-06 Aveve Nv Phytathydrolyse og enzymsammensætning til hydrolyse af phytat
ES2130440T3 (es) * 1993-08-11 1999-07-01 Hokko Chem Ind Co Proceso para producir d-(quiro)-inositol.
SE502574C2 (sv) * 1994-01-25 1995-11-13 Perstorp Ab En farmaceutisk komposition med förbättrad biotillgänglighet hos inositolfosfat
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US5880099A (en) * 1996-09-20 1999-03-09 The Regents Of The University Of California Inositol polyphosphates and methods of using same
US5977078A (en) * 1996-09-20 1999-11-02 The Regents Of The Univesity Of California Inositol polyphosphate derivatives and methods of using same
US5998485A (en) * 1997-06-16 1999-12-07 Cedars-Sinai Medical Center Method for modulating immune response with inositol
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DE10031955A1 (de) * 2000-06-30 2002-01-17 Deutsches Krebsforsch Curcumin-Derivate mit gegenüber Curcumin verbesserter Wasserlöslichkeit und diese enthaltende Arzneimittel
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US7521481B2 (en) * 2003-02-27 2009-04-21 Mclaurin Joanne Methods of preventing, treating and diagnosing disorders of protein aggregation
ATE458042T1 (de) * 2003-10-14 2010-03-15 Hokko Chem Ind Co Verfahren zur herstellung von scyllo-inositol
EP2186518A1 (en) * 2004-11-17 2010-05-19 McLaurin, Joanne Composition and methods for treatment of disorders of protein aggregation

Also Published As

Publication number Publication date
AU2007222864A1 (en) 2007-09-13
IL193970A0 (en) 2009-08-03
CN103054837A (zh) 2013-04-24
EA200801967A1 (ru) 2009-04-28
AU2007222864A8 (en) 2010-06-10
WO2007101353A1 (en) 2007-09-13
BRPI0708725A2 (pt) 2011-06-07
EP1996175A1 (en) 2008-12-03
EP1996175A4 (en) 2009-06-10
US20100113613A1 (en) 2010-05-06
MX2008011553A (es) 2008-12-09
JP2009529502A (ja) 2009-08-20
ZA200908303B (en) 2012-08-29
NZ571181A (en) 2011-12-22
KR20090026247A (ko) 2009-03-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20140922