ZA200907643B - Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof - Google Patents

Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Info

Publication number
ZA200907643B
ZA200907643B ZA2009/07643A ZA200907643A ZA200907643B ZA 200907643 B ZA200907643 B ZA 200907643B ZA 2009/07643 A ZA2009/07643 A ZA 2009/07643A ZA 200907643 A ZA200907643 A ZA 200907643A ZA 200907643 B ZA200907643 B ZA 200907643B
Authority
ZA
South Africa
Prior art keywords
methylpyrrolidine
preparing
processes
tartrate salts
tartrate
Prior art date
Application number
ZA2009/07643A
Other languages
English (en)
Inventor
Michael Christie
Joseph James Petraitis
Original Assignee
Cephalon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cephalon Inc filed Critical Cephalon Inc
Publication of ZA200907643B publication Critical patent/ZA200907643B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Catalysts (AREA)
ZA2009/07643A 2007-05-03 2009-10-30 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof ZA200907643B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US92735607P 2007-05-03 2007-05-03
PCT/US2008/005702 WO2008137087A1 (en) 2007-05-03 2008-05-02 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Publications (1)

Publication Number Publication Date
ZA200907643B true ZA200907643B (en) 2014-03-26

Family

ID=39688886

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2009/07643A ZA200907643B (en) 2007-05-03 2009-10-30 Processes for preparing (r)-2-methylpyrrolidine and (s)-2-methylpyrrolidine and tartrate salts thereof

Country Status (14)

Country Link
EP (1) EP2152669A1 (Direct)
JP (1) JP5698887B2 (Direct)
KR (1) KR20100017565A (Direct)
CN (1) CN101679237A (Direct)
AU (1) AU2008248168B2 (Direct)
BR (1) BRPI0810330A2 (Direct)
CA (1) CA2686033A1 (Direct)
EA (1) EA019031B1 (Direct)
IL (1) IL201627A (Direct)
MX (1) MX2009011787A (Direct)
NZ (1) NZ580948A (Direct)
UA (1) UA99913C2 (Direct)
WO (1) WO2008137087A1 (Direct)
ZA (1) ZA200907643B (Direct)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA017004B1 (ru) 2006-07-25 2012-09-28 Сефалон, Инк. Пиридизиноновые производные
US8383657B2 (en) 2007-12-21 2013-02-26 Abbott Laboratories Thiazolylidine urea and amide derivatives and methods of use thereof
WO2009097306A1 (en) * 2008-01-30 2009-08-06 Cephalon, Inc. Substituted pyridazine derivatives which have histamine h3 antagonist activity
ES2707123T3 (es) * 2014-12-23 2019-04-02 Cephalon Inc Métodos para la preparación de derivados 2, 4-diaminopirimidin bicíclicos fusionados
AU2019335542A1 (en) * 2018-09-07 2021-04-01 Sanofi Process for the preparation of methyl 6-(2,4-dichlorophenyl)-5-(4-((3s)-1-(3-fluoropropyl)pyrrolidin-3-yl)oxyphenyl)-8,9-dihydro-7H-benzo(7)annulene-2-carboxylate

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3329974A1 (de) 1983-08-19 1985-02-28 Bayer Ag, 5090 Leverkusen Herstellung von hydrierten nitrilkautschuken
DE3433392A1 (de) 1984-09-12 1986-03-20 Bayer Ag, 5090 Leverkusen Hydrierung nitrilgruppenhaltiger ungesaettigter polymerer
FR2714849B1 (fr) 1994-01-13 1996-04-05 Inst Francais Du Petrole Procédé de préparation d'un catalyseur d'hydrogénation soluble en phase liquide organique.
DE4403479A1 (de) 1994-02-04 1995-08-10 Basf Ag Verfahren zur Herstellung von Hydroxylammoniumsalzen
WO2004024707A2 (en) * 2002-09-16 2004-03-25 Abbott Laboratories Process for preparing amine type substituted benzofurans
US7153889B2 (en) 2002-11-12 2006-12-26 Abbott Laboratories Bicyclic-substituted amines as histamine-3 receptor ligands
US8110519B2 (en) 2004-03-08 2012-02-07 Japan Science & Technology Agency Polymer-supported metal cluster composition
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
BRPI0511778A (pt) 2004-06-02 2008-01-15 Hoffmann La Roche derivados da naftalina úteis como ligantes do receptor 3 da histamina
US8158652B2 (en) 2004-12-01 2012-04-17 Msd K.K. Substituted pyridone derivative
AU2005316337A1 (en) 2004-12-17 2006-06-22 Janssen Pharmaceutica, N.V. Tetrahydroisoquinoline compounds for treatment of CNS disorders
WO2006078775A1 (en) 2005-01-21 2006-07-27 Schering Corporation Imidazole and benzimidazole derivatives useful as histamine h3 antagonists
JP2008534542A (ja) 2005-03-31 2008-08-28 ユセベ ファルマ ソシエテ アノニム オキサゾール部分又はチアゾール部分を含む化合物、それらの製造方法及びそれらの使用
GB0514812D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds
AU2006308167A1 (en) 2005-10-27 2007-05-03 Ucb Pharma, S.A. Compounds comprising a lactam or a lactam derivative moiety, processes for making them, and their uses
WO2007094962A2 (en) 2006-02-09 2007-08-23 Athersys, Inc. Pyrazoles for the treatment of obesity and other cns disorders
WO2007099423A1 (en) 2006-03-02 2007-09-07 Pfizer Products Inc. 1-pyrrolidine indane derivatives as histamine-3 receptor antagonists
US20090163482A1 (en) 2006-03-13 2009-06-25 Mchardy Stanton Furst Tetralines antagonists of the h-3 receptor
EP2035372A1 (en) 2006-06-29 2009-03-18 Arena Pharmaceuticals, Inc. Modulators of the histamine h3-receptor useful for the treatment of disorders related thereto
EA017004B1 (ru) 2006-07-25 2012-09-28 Сефалон, Инк. Пиридизиноновые производные

Also Published As

Publication number Publication date
EA200971019A1 (ru) 2010-04-30
WO2008137087A1 (en) 2008-11-13
CA2686033A1 (en) 2008-11-13
UA99913C2 (ru) 2012-10-25
IL201627A0 (en) 2010-05-31
JP5698887B2 (ja) 2015-04-08
EP2152669A1 (en) 2010-02-17
EA019031B1 (ru) 2013-12-30
CN101679237A (zh) 2010-03-24
BRPI0810330A2 (pt) 2014-10-14
JP2010526142A (ja) 2010-07-29
KR20100017565A (ko) 2010-02-16
IL201627A (en) 2014-06-30
MX2009011787A (es) 2009-11-13
AU2008248168B2 (en) 2013-03-21
AU2008248168A1 (en) 2008-11-13
NZ580948A (en) 2011-04-29

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