ZA200904470B - Gelatin-transglutaminase hemostatic dressings and sealants - Google Patents

Gelatin-transglutaminase hemostatic dressings and sealants

Info

Publication number
ZA200904470B
ZA200904470B ZA200904470A ZA200904470A ZA200904470B ZA 200904470 B ZA200904470 B ZA 200904470B ZA 200904470 A ZA200904470 A ZA 200904470A ZA 200904470 A ZA200904470 A ZA 200904470A ZA 200904470 B ZA200904470 B ZA 200904470B
Authority
ZA
South Africa
Prior art keywords
sealants
gelatin
hemostatic dressings
transglutaminase
transglutaminase hemostatic
Prior art date
Application number
ZA200904470A
Other languages
English (en)
Inventor
Orahn Preiss-Bloom
Ishay Attar
Natalie Iram
Original Assignee
Lifebond Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39733194&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200904470(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lifebond Ltd filed Critical Lifebond Ltd
Publication of ZA200904470B publication Critical patent/ZA200904470B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A61L15/325Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/10Polypeptides; Proteins
    • A61L24/104Gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0038Gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/04Materials for stopping bleeding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200904470A 2006-12-15 2009-06-26 Gelatin-transglutaminase hemostatic dressings and sealants ZA200904470B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87515006P 2006-12-15 2006-12-15

Publications (1)

Publication Number Publication Date
ZA200904470B true ZA200904470B (en) 2010-04-28

Family

ID=39733194

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200904470A ZA200904470B (en) 2006-12-15 2009-06-26 Gelatin-transglutaminase hemostatic dressings and sealants

Country Status (5)

Country Link
US (1) US8133484B2 (xx)
EP (2) EP2586467B1 (xx)
CN (1) CN105079871A (xx)
CA (1) CA2836067C (xx)
ZA (1) ZA200904470B (xx)

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CN101854960B (zh) 2006-12-15 2014-06-25 生命连结有限公司 明胶-转谷氨酰胺酶止血敷料和密封材料
WO2009153750A2 (en) 2008-06-18 2009-12-23 Lifebond Ltd Improved cross-linked compositions
JP2012529976A (ja) * 2009-06-15 2012-11-29 セラマテック インコーポレイテッド 止血性材料および送達デバイス
US9066991B2 (en) * 2009-12-22 2015-06-30 Lifebond Ltd. Modification of enzymatic crosslinkers for controlling properties of crosslinked matrices
WO2012017415A2 (en) 2010-08-05 2012-02-09 Lifebond Ltd. Dry composition wound dressings and adhesives
US9492952B2 (en) 2010-08-30 2016-11-15 Endo-Surgery, Inc. Super-hydrophilic structures
US20120143228A1 (en) 2010-08-30 2012-06-07 Agency For Science Technology And Research Adhesive structure with stiff protrusions on adhesive surface
US9447169B2 (en) * 2011-03-04 2016-09-20 Orthovita, Inc. Flowable collagen-based hemostat and methods of use
CN104220079B (zh) 2011-12-29 2018-01-12 伊西康公司 在其表面上具有组织穿刺突起的粘合结构
US8969648B2 (en) 2012-04-06 2015-03-03 Ethicon, Inc. Blood clotting substrate and medical device
US8926881B2 (en) 2012-04-06 2015-01-06 DePuy Synthes Products, LLC Super-hydrophobic hierarchical structures, method of forming them and medical devices incorporating them
WO2014112208A1 (ja) * 2013-01-18 2014-07-24 独立行政法人物質・材料研究機構 組織接着剤及びその製造方法
US9446166B2 (en) 2013-01-24 2016-09-20 Ethicon, Inc. Fibrin sealant compositions with chemical crosslinking
US10124084B2 (en) 2014-03-24 2018-11-13 Datt Life Sciences Private Limited Ready to use biodegradable and biocompatible device and a method of preparation thereof
US10660945B2 (en) 2015-08-07 2020-05-26 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
US10751444B2 (en) 2015-08-07 2020-08-25 Victor Matthew Phillips Flowable hemostatic gel composition and its methods of use
CN105288638B (zh) * 2015-10-27 2018-07-06 江苏金维氨生物工程有限公司 一种提高支链氨基酸粉剂堆积密度的方法
US20210353501A1 (en) * 2017-03-31 2021-11-18 Medcura, Inc. Hydrophobically-modified polymer foams and methods of use
WO2019049927A1 (ja) 2017-09-07 2019-03-14 天野エンザイム株式会社 安定化蛋白質脱アミド酵素乾燥組成物
CA3078432A1 (en) * 2017-10-04 2019-05-09 Bio-Change Ltd. Cross-linked protein foams and methods of using thereof a polyvalent cellular scaffold
CN108478849B (zh) * 2018-02-07 2021-04-16 广州迈普再生医学科技股份有限公司 一种可吸收可黏附止血海绵及其制备方法
CN111068102B (zh) * 2019-12-18 2022-04-12 陕西科技大学 酶促凝血抗菌可控的明胶基水凝胶及其制备方法
CN114939185B (zh) * 2022-05-19 2023-03-24 北京化工大学 一种阳离子化多糖多酚复合止血涂层的制备方法
CN115737905B (zh) * 2022-11-01 2023-12-08 重庆工商大学 一种负载纳米二氧化硅的人工骨膜及其制备方法和应用

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US2398004A (en) 1943-07-20 1946-04-09 Eastman Kodak Co Controlling the isoelectric point of gelatin
US2558065A (en) 1949-05-03 1951-06-26 Linwood F Tice Method of preparing solutions of gelatin in polyhydric alcohols
US2803548A (en) 1955-02-07 1957-08-20 Louis Milani Foods Inc Method of making gelatin-containing food preparations which dissolve at room temperature and gel at room temperature
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Also Published As

Publication number Publication date
EP2455109A2 (en) 2012-05-23
EP2586467A3 (en) 2013-07-17
CA2836067A1 (en) 2008-06-26
EP2455109B1 (en) 2015-02-11
US20080213243A1 (en) 2008-09-04
US8133484B2 (en) 2012-03-13
EP2586467B1 (en) 2018-05-02
EP2455109B2 (en) 2021-11-03
CN105079871A (zh) 2015-11-25
CA2836067C (en) 2016-02-09
EP2586467A2 (en) 2013-05-01
EP2455109A3 (en) 2012-06-13

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