ZA200904378B - Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same - Google Patents
Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the sameInfo
- Publication number
- ZA200904378B ZA200904378B ZA200904378A ZA200904378A ZA200904378B ZA 200904378 B ZA200904378 B ZA 200904378B ZA 200904378 A ZA200904378 A ZA 200904378A ZA 200904378 A ZA200904378 A ZA 200904378A ZA 200904378 B ZA200904378 B ZA 200904378B
- Authority
- ZA
- South Africa
- Prior art keywords
- pharmaceutical composition
- same
- composition containing
- maleic acid
- antiviral agent
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20070005269 | 2007-01-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200904378B true ZA200904378B (en) | 2010-05-26 |
Family
ID=39636116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200904378A ZA200904378B (en) | 2007-01-17 | 2009-06-23 | Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same |
Country Status (17)
Country | Link |
---|---|
US (1) | US20090325904A1 (ja) |
EP (1) | EP2124953A4 (ja) |
JP (1) | JP4980431B2 (ja) |
KR (1) | KR100935904B1 (ja) |
CN (1) | CN101616674B (ja) |
AR (1) | AR064915A1 (ja) |
BR (1) | BRPI0806461B8 (ja) |
CA (1) | CA2673510C (ja) |
CL (1) | CL2008000070A1 (ja) |
CO (1) | CO6210809A2 (ja) |
EA (1) | EA015269B1 (ja) |
MX (1) | MX2009006826A (ja) |
MY (1) | MY163479A (ja) |
TW (1) | TWI384986B (ja) |
UA (1) | UA91655C2 (ja) |
WO (1) | WO2008088147A1 (ja) |
ZA (1) | ZA200904378B (ja) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103665043B (zh) | 2012-08-30 | 2017-11-10 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药及其在医药上的应用 |
JP2018504891A (ja) * | 2014-12-31 | 2018-02-22 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | リアルタイムPCRによる細胞溶解物からのHBV cccDNA定量化のための新規ハイスループット法 |
CN106977548A (zh) * | 2016-01-19 | 2017-07-25 | 四川海思科制药有限公司 | 倍司福韦复合物及其制备方法和用途 |
KR102623581B1 (ko) | 2016-07-18 | 2024-01-11 | 일동제약(주) | 항바이러스성 약물의 오로트산염, 이의 제조 방법 및 상기 염을 포함하는 약제학적 조성물 |
KR101899773B1 (ko) * | 2017-03-07 | 2018-09-18 | 일동제약(주) | 베시포비르 디피복실 또는 이의 약제학적 허용되는 염 함유 과립, 상기 과립을 포함하는 약제학적 조성물 및 이의 제조 방법 |
Family Cites Families (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2887481A (en) * | 1957-04-29 | 1959-05-19 | Schering Corp | Heterocyclic amides |
US3832460A (en) * | 1971-03-19 | 1974-08-27 | C Kosti | Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue |
DK161312C (da) * | 1982-03-11 | 1991-12-09 | Pfizer | Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden |
NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
WO1994012497A1 (en) * | 1992-11-20 | 1994-06-09 | Taisho Pharmaceutical Co., Ltd. | Heterocyclic compound |
EP0620222A3 (en) * | 1993-04-14 | 1995-04-12 | Lilly Co Eli | Tetrahydro-beta-carbolines. |
US5795909A (en) * | 1996-05-22 | 1998-08-18 | Neuromedica, Inc. | DHA-pharmaceutical agent conjugates of taxanes |
US6624138B1 (en) * | 2001-09-27 | 2003-09-23 | Gp Medical | Drug-loaded biological material chemically treated with genipin |
MY141789A (en) * | 2001-01-19 | 2010-06-30 | Lg Chem Investment Ltd | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same. |
US7927613B2 (en) * | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
EP1546164A4 (en) * | 2002-09-26 | 2006-06-07 | Lg Life Sciences Ltd | (+) - TRANS-ISOMERS OF (1-PHOSPHONOMETHOXY-2-ALKYLCYCLOPROPYL) METHYL NUCLEOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION OF STEREO-ISOMERS THEREOF, AND THE USE OF ANTIVIRAL AGENTS PRODUCED THEREOF |
AU2003268687A1 (en) * | 2002-09-30 | 2004-04-19 | Yamanouchi Pharmaceutical Co., Ltd. | Novel salt of 2-acylaminothiazole derivative |
US7167750B2 (en) * | 2003-02-03 | 2007-01-23 | Enteromedics, Inc. | Obesity treatment with electrically induced vagal down regulation |
PT1670785E (pt) * | 2003-10-02 | 2010-09-16 | Pharmacia & Upjohn Co Llc | Sais e polimorfos de um composto de indolinona substituída com pirrole |
GB0330002D0 (en) * | 2003-12-24 | 2004-01-28 | Astrazeneca Ab | Quinazoline derivatives |
TW200533358A (en) * | 2004-02-17 | 2005-10-16 | Anadys Pharmaceuticals Inc | Nucleoside phosphonate derivatives useful in the treatment of hiv infections |
WO2005105740A2 (en) * | 2004-04-26 | 2005-11-10 | Teva Pharmaceutical Industries Ltd. | Preparation of tegaserod and tegaserod maleate |
KR101033290B1 (ko) * | 2004-07-02 | 2011-05-09 | 주식회사 엘지생명과학 | 다이아이소프로필((1-(하이드록시메틸)-사이클로프로필)옥시)메틸포스포네이트의 새로운 제조 방법 |
DE102005034974A1 (de) * | 2005-07-22 | 2007-04-19 | Grünenthal GmbH | Salz von Dimethylaminomethyl-phenyl-cyclohexan und dessen kristalline Formen |
US7928226B2 (en) * | 2005-08-08 | 2011-04-19 | Agouron Pharmaceuticals Inc. | Salts and polymorphs of a VEGF-R inhibitor |
EP1948608B1 (en) * | 2005-11-08 | 2012-03-14 | Millennium Pharmaceuticals, Inc. | Pharmaceutical salts and polymorphs of n-(5-chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxy-benzamide , a factor xa inhibitor |
WO2008033466A2 (en) * | 2006-09-14 | 2008-03-20 | Combinatorx (Singapore) Pre. Ltd. | Compositions and methods for treatment of viral diseases |
MX2009003410A (es) * | 2006-09-29 | 2009-07-17 | Idenix Pharmaceuticals Inc | Fosfoindoles enantiomericamente puros como inhibidores de vih. |
-
2008
- 2008-01-10 TW TW097100957A patent/TWI384986B/zh active
- 2008-01-10 CL CL200800070A patent/CL2008000070A1/es unknown
- 2008-01-11 US US12/522,046 patent/US20090325904A1/en not_active Abandoned
- 2008-01-11 EA EA200970690A patent/EA015269B1/ru unknown
- 2008-01-11 CA CA2673510A patent/CA2673510C/en active Active
- 2008-01-11 EP EP08704733A patent/EP2124953A4/en not_active Withdrawn
- 2008-01-11 MY MYPI20092745A patent/MY163479A/en unknown
- 2008-01-11 CN CN2008800025393A patent/CN101616674B/zh active Active
- 2008-01-11 JP JP2009546316A patent/JP4980431B2/ja active Active
- 2008-01-11 UA UAA200907518A patent/UA91655C2/ru unknown
- 2008-01-11 WO PCT/KR2008/000194 patent/WO2008088147A1/en active Application Filing
- 2008-01-11 BR BRPI0806461A patent/BRPI0806461B8/pt active IP Right Grant
- 2008-01-11 MX MX2009006826A patent/MX2009006826A/es active IP Right Grant
- 2008-01-14 KR KR1020080004100A patent/KR100935904B1/ko active Protection Beyond IP Right Term
- 2008-01-16 AR ARP080100182A patent/AR064915A1/es not_active Application Discontinuation
-
2009
- 2009-06-23 ZA ZA200904378A patent/ZA200904378B/xx unknown
- 2009-07-17 CO CO09074840A patent/CO6210809A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BRPI0806461B8 (pt) | 2021-05-25 |
CL2008000070A1 (es) | 2008-07-25 |
BRPI0806461A2 (pt) | 2011-09-06 |
CO6210809A2 (es) | 2010-10-20 |
AR064915A1 (es) | 2009-05-06 |
CN101616674A (zh) | 2009-12-30 |
BRPI0806461B1 (pt) | 2019-09-03 |
EP2124953A1 (en) | 2009-12-02 |
US20090325904A1 (en) | 2009-12-31 |
CA2673510C (en) | 2012-08-21 |
UA91655C2 (ru) | 2010-08-10 |
CA2673510A1 (en) | 2008-07-24 |
KR100935904B1 (ko) | 2010-01-07 |
EA015269B1 (ru) | 2011-06-30 |
JP4980431B2 (ja) | 2012-07-18 |
JP2010516668A (ja) | 2010-05-20 |
TW200836744A (en) | 2008-09-16 |
EP2124953A4 (en) | 2011-02-09 |
MY163479A (en) | 2017-09-15 |
KR20080067969A (ko) | 2008-07-22 |
EA200970690A1 (ru) | 2009-12-30 |
MX2009006826A (es) | 2009-07-02 |
CN101616674B (zh) | 2012-06-13 |
TWI384986B (zh) | 2013-02-11 |
WO2008088147A1 (en) | 2008-07-24 |
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