ZA200904378B - Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same - Google Patents

Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same

Info

Publication number
ZA200904378B
ZA200904378B ZA200904378A ZA200904378A ZA200904378B ZA 200904378 B ZA200904378 B ZA 200904378B ZA 200904378 A ZA200904378 A ZA 200904378A ZA 200904378 A ZA200904378 A ZA 200904378A ZA 200904378 B ZA200904378 B ZA 200904378B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical composition
same
composition containing
maleic acid
antiviral agent
Prior art date
Application number
ZA200904378A
Other languages
English (en)
Inventor
Ki Sook Park
Ji Hye Lee
Jung Min Yun
Original Assignee
Lg Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd filed Critical Lg Life Sciences Ltd
Publication of ZA200904378B publication Critical patent/ZA200904378B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • A61K31/41621,2-Diazoles condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
ZA200904378A 2007-01-17 2009-06-23 Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same ZA200904378B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20070005269 2007-01-17

Publications (1)

Publication Number Publication Date
ZA200904378B true ZA200904378B (en) 2010-05-26

Family

ID=39636116

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200904378A ZA200904378B (en) 2007-01-17 2009-06-23 Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same

Country Status (17)

Country Link
US (1) US20090325904A1 (ja)
EP (1) EP2124953A4 (ja)
JP (1) JP4980431B2 (ja)
KR (1) KR100935904B1 (ja)
CN (1) CN101616674B (ja)
AR (1) AR064915A1 (ja)
BR (1) BRPI0806461B8 (ja)
CA (1) CA2673510C (ja)
CL (1) CL2008000070A1 (ja)
CO (1) CO6210809A2 (ja)
EA (1) EA015269B1 (ja)
MX (1) MX2009006826A (ja)
MY (1) MY163479A (ja)
TW (1) TWI384986B (ja)
UA (1) UA91655C2 (ja)
WO (1) WO2008088147A1 (ja)
ZA (1) ZA200904378B (ja)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103665043B (zh) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 一种替诺福韦前药及其在医药上的应用
JP2018504891A (ja) * 2014-12-31 2018-02-22 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft リアルタイムPCRによる細胞溶解物からのHBV cccDNA定量化のための新規ハイスループット法
CN106977548A (zh) * 2016-01-19 2017-07-25 四川海思科制药有限公司 倍司福韦复合物及其制备方法和用途
KR102623581B1 (ko) 2016-07-18 2024-01-11 일동제약(주) 항바이러스성 약물의 오로트산염, 이의 제조 방법 및 상기 염을 포함하는 약제학적 조성물
KR101899773B1 (ko) * 2017-03-07 2018-09-18 일동제약(주) 베시포비르 디피복실 또는 이의 약제학적 허용되는 염 함유 과립, 상기 과립을 포함하는 약제학적 조성물 및 이의 제조 방법

Family Cites Families (23)

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US2887481A (en) * 1957-04-29 1959-05-19 Schering Corp Heterocyclic amides
US3832460A (en) * 1971-03-19 1974-08-27 C Kosti Anesthetic-vasoconstrictor-antihistamine composition for the treatment of hypertrophied oral tissue
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
WO1994012497A1 (en) * 1992-11-20 1994-06-09 Taisho Pharmaceutical Co., Ltd. Heterocyclic compound
EP0620222A3 (en) * 1993-04-14 1995-04-12 Lilly Co Eli Tetrahydro-beta-carbolines.
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
US6624138B1 (en) * 2001-09-27 2003-09-23 Gp Medical Drug-loaded biological material chemically treated with genipin
MY141789A (en) * 2001-01-19 2010-06-30 Lg Chem Investment Ltd Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same.
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
EP1546164A4 (en) * 2002-09-26 2006-06-07 Lg Life Sciences Ltd (+) - TRANS-ISOMERS OF (1-PHOSPHONOMETHOXY-2-ALKYLCYCLOPROPYL) METHYL NUCLEOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION OF STEREO-ISOMERS THEREOF, AND THE USE OF ANTIVIRAL AGENTS PRODUCED THEREOF
AU2003268687A1 (en) * 2002-09-30 2004-04-19 Yamanouchi Pharmaceutical Co., Ltd. Novel salt of 2-acylaminothiazole derivative
US7167750B2 (en) * 2003-02-03 2007-01-23 Enteromedics, Inc. Obesity treatment with electrically induced vagal down regulation
PT1670785E (pt) * 2003-10-02 2010-09-16 Pharmacia & Upjohn Co Llc Sais e polimorfos de um composto de indolinona substituída com pirrole
GB0330002D0 (en) * 2003-12-24 2004-01-28 Astrazeneca Ab Quinazoline derivatives
TW200533358A (en) * 2004-02-17 2005-10-16 Anadys Pharmaceuticals Inc Nucleoside phosphonate derivatives useful in the treatment of hiv infections
WO2005105740A2 (en) * 2004-04-26 2005-11-10 Teva Pharmaceutical Industries Ltd. Preparation of tegaserod and tegaserod maleate
KR101033290B1 (ko) * 2004-07-02 2011-05-09 주식회사 엘지생명과학 다이아이소프로필((1-(하이드록시메틸)-사이클로프로필)옥시)메틸포스포네이트의 새로운 제조 방법
DE102005034974A1 (de) * 2005-07-22 2007-04-19 Grünenthal GmbH Salz von Dimethylaminomethyl-phenyl-cyclohexan und dessen kristalline Formen
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WO2008033466A2 (en) * 2006-09-14 2008-03-20 Combinatorx (Singapore) Pre. Ltd. Compositions and methods for treatment of viral diseases
MX2009003410A (es) * 2006-09-29 2009-07-17 Idenix Pharmaceuticals Inc Fosfoindoles enantiomericamente puros como inhibidores de vih.

Also Published As

Publication number Publication date
BRPI0806461B8 (pt) 2021-05-25
CL2008000070A1 (es) 2008-07-25
BRPI0806461A2 (pt) 2011-09-06
CO6210809A2 (es) 2010-10-20
AR064915A1 (es) 2009-05-06
CN101616674A (zh) 2009-12-30
BRPI0806461B1 (pt) 2019-09-03
EP2124953A1 (en) 2009-12-02
US20090325904A1 (en) 2009-12-31
CA2673510C (en) 2012-08-21
UA91655C2 (ru) 2010-08-10
CA2673510A1 (en) 2008-07-24
KR100935904B1 (ko) 2010-01-07
EA015269B1 (ru) 2011-06-30
JP4980431B2 (ja) 2012-07-18
JP2010516668A (ja) 2010-05-20
TW200836744A (en) 2008-09-16
EP2124953A4 (en) 2011-02-09
MY163479A (en) 2017-09-15
KR20080067969A (ko) 2008-07-22
EA200970690A1 (ru) 2009-12-30
MX2009006826A (es) 2009-07-02
CN101616674B (zh) 2012-06-13
TWI384986B (zh) 2013-02-11
WO2008088147A1 (en) 2008-07-24

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