ZA200903874B - Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane carboxylates - Google Patents

Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane carboxylates

Info

Publication number
ZA200903874B
ZA200903874B ZA200903874A ZA200903874A ZA200903874B ZA 200903874 B ZA200903874 B ZA 200903874B ZA 200903874 A ZA200903874 A ZA 200903874A ZA 200903874 A ZA200903874 A ZA 200903874A ZA 200903874 B ZA200903874 B ZA 200903874B
Authority
ZA
South Africa
Prior art keywords
phenylcyclopentane
carboxylates
isolation
amino
substituted
Prior art date
Application number
ZA200903874A
Other languages
English (en)
Inventor
Thomas D Gordon
Grier A Wallace
Martin E Hayes
Kirill A Lukin
Lei Wang
Dilinie P Fernando
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of ZA200903874B publication Critical patent/ZA200903874B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/24—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from hydantoins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/26—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing carboxyl groups by reaction with HCN, or a salt thereof, and amines, or from aminonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/30—Preparation of optical isomers
    • C07C227/34—Preparation of optical isomers by separation of optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/69—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by addition to carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200903874A 2006-12-21 2009-06-03 Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane carboxylates ZA200903874B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87625106P 2006-12-21 2006-12-21

Publications (1)

Publication Number Publication Date
ZA200903874B true ZA200903874B (en) 2010-04-28

Family

ID=39562855

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200903874A ZA200903874B (en) 2006-12-21 2009-06-03 Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane carboxylates

Country Status (9)

Country Link
US (1) US7956195B2 (xx)
EP (1) EP2102145A4 (xx)
JP (1) JP2010513531A (xx)
CN (1) CN101563316A (xx)
CA (1) CA2673076A1 (xx)
MX (1) MX2009006748A (xx)
RU (1) RU2009128063A (xx)
WO (1) WO2008079380A1 (xx)
ZA (1) ZA200903874B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2655319B1 (de) * 2010-12-22 2019-05-08 Bayer CropScience Aktiengesellschaft Verfahren zur herstellung von cis-1-ammonium-4-alkoxycyclohexancarbonitrilsalzen
CN107759483B (zh) * 2016-08-16 2022-03-11 浙江瑞博制药有限公司 一种甲氨基取代的环戊烷甲酸烷基酯的制备方法
CN115847629B (zh) * 2022-11-30 2023-09-29 江苏富乐徳石英科技有限公司 一种高效节能环保的石英环制备工艺

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
JP3333510B2 (ja) * 1991-10-02 2002-10-15 スミスクライン・ビーチャム・コーポレイション 抗アレルギー、抗炎症および腫瘍壊死因子抑制活性を有するシクロペンタンおよびシクロペンテン誘導体
US5314896A (en) 1991-11-20 1994-05-24 Warner-Lambert Company 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents
US20020052370A1 (en) * 2000-07-06 2002-05-02 Barber Christopher Gordon Cyclopentyl-substituted glutaramide derivatives as inhibitors of neutral endopeptidase
EP1188826B1 (en) * 2000-09-13 2011-06-08 Ajinomoto Co., Inc. 5-substituted hydantoin racemase, DNA coding for the same, and process for producing optically active amino acids
US20060051846A1 (en) * 2002-09-06 2006-03-09 Kaneka Corporation Process for producing l-alpha-methylcysteine derivative
AR043050A1 (es) * 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
US7256198B2 (en) * 2004-02-18 2007-08-14 Wyeth Pyrimidoindolones and methods for using same
WO2006064189A1 (en) * 2004-12-14 2006-06-22 Astrazeneca Ab Oxadiazole derivatives as dgat inhibitors
AU2006214314B2 (en) 2005-02-14 2012-02-09 University Of Virginia Patent Foundation Sphingosine 1- phos phate agonists comprising cycloalkanes and 5 -membered heterocycles substituted by amino and phenyl groups
US7521557B2 (en) * 2005-05-20 2009-04-21 Bristol-Myers Squibb Company Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
JP2009528274A (ja) * 2006-01-27 2009-08-06 ユニバーシティ オブ バージニア パテント ファンデーション 神経因性疼痛の治療法
RU2008137553A (ru) 2006-02-21 2010-03-27 Юниверсити Оф Вирджиния Пэтент Фаундейшн (Us) Фенил-циклоалкильные соединения, содержащие гетероциклические структуры
WO2008079382A1 (en) * 2006-12-21 2008-07-03 Abbott Laboratories Sphingosine-1 -phosphate receptor agonist and antagonist compounds

Also Published As

Publication number Publication date
WO2008079380A1 (en) 2008-07-03
US20080255367A1 (en) 2008-10-16
RU2009128063A (ru) 2011-01-27
US7956195B2 (en) 2011-06-07
EP2102145A1 (en) 2009-09-23
MX2009006748A (es) 2009-06-30
CN101563316A (zh) 2009-10-21
JP2010513531A (ja) 2010-04-30
EP2102145A4 (en) 2014-06-18
CA2673076A1 (en) 2008-07-03

Similar Documents

Publication Publication Date Title
DK3872058T3 (en) Process for the preparation of 2,3,3,3 tetrahydrofluoropropene
IL206100A0 (en) Process for the preparation of macrocycle
EG25430A (en) Beverage precursor and process for the manufacturethereof
HK1141013A1 (en) Process for the preparation of certain substituted sulfilimines
ZA200805939B (en) Azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
IL198847A0 (en) New process for the preparation of 2-imino-thiazolidin-4-one derivatives
ZA200900336B (en) Process for the preparation of diesters
IL193236A0 (en) Novel pyrone-indole derivatives and process for their preparation
IL193341A0 (en) Novel azacyclyl-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
IL193339A0 (en) Novel aminoalcohol-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
PL2151428T3 (pl) Nowy sposób syntezy agomelatyny
ZA200907191B (en) Process for the preparation of gefitiib
ZA200808011B (en) Process for the isolation of calliterpenone (16alpha, 17-DiHyDroxy-S-Oxo-Phyllocladane)
PL2044099T3 (pl) Sposób wytwarzania S-fluorometylo-6,9-difluoro-11-hydroksy-16-metylo-17-propionyloksy-3-okso-androsta-1,4-dieno-17-karbotionianu oraz związki pośrednie
IL198437A0 (en) Membrane station treatment process
PL2151429T3 (pl) Nowy sposób syntezy agomelatyny
EP2083003A4 (en) PROCESS FOR THE PREPARATION OF 1,1,1,3,3-PENTACHLOROBUTANE
IL211975A (en) Process for the preparation of 9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalene-5-ylamine and intermediate compounds
ZA201003507B (en) Novel naphthyridine derivative monohydrate and method for producing the same
ZA200903874B (en) Process for the preparation and isolation of the individual stereoisomers of 1-amino, 3-substituted phenylcyclopentane carboxylates
EP1996192A4 (en) PROCESS FOR PREPARING 3,4-SUBSTITUTED THIAZOLIDIN-2-ONES IN 3,4
EG26041A (en) Method for the manufacture of black tea beverage from raw material (theanine)
GB2469980A8 (en) Novel napthalimide-benzimidazole hybrids as potential antitumour agents and process for the preparation thereof.
HK1168845A1 (en) Process for the preparation of (1s,4r)-2-oxa-3-azabicyclo[2.2.1]hept-5-enes (1s4r)-2--3-[221]-5-
ZA201003264B (en) Method for the preparation of 2 chloro1,1,1,2,3,3,3 heptafluopropane