ZA200903278B - Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors - Google Patents

Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Info

Publication number
ZA200903278B
ZA200903278B ZA200903278A ZA200903278A ZA200903278B ZA 200903278 B ZA200903278 B ZA 200903278B ZA 200903278 A ZA200903278 A ZA 200903278A ZA 200903278 A ZA200903278 A ZA 200903278A ZA 200903278 B ZA200903278 B ZA 200903278B
Authority
ZA
South Africa
Prior art keywords
derivatives
uptake inhibitors
monoamine neurotransmitter
novel chromen
chromen
Prior art date
Application number
ZA200903278A
Other languages
English (en)
Inventor
Dan Peters
John Paul Redrobe
Gunnar M Olsen
Elsebet Ostergaard Nielsen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Publication of ZA200903278B publication Critical patent/ZA200903278B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200903278A 2006-12-20 2007-12-18 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors ZA200903278B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200601678 2006-12-20

Publications (1)

Publication Number Publication Date
ZA200903278B true ZA200903278B (en) 2010-07-28

Family

ID=40639626

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200903278A ZA200903278B (en) 2006-12-20 2007-12-18 Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors

Country Status (12)

Country Link
KR (1) KR20090089439A (pt)
CN (1) CN101563344B (pt)
AR (1) AR064457A1 (pt)
AT (1) ATE486868T1 (pt)
BR (1) BRPI0719578A2 (pt)
DE (1) DE602007010356D1 (pt)
DK (1) DK2121677T3 (pt)
NZ (1) NZ577071A (pt)
PT (1) PT2121677E (pt)
RU (1) RU2009119919A (pt)
TW (1) TW200836732A (pt)
ZA (1) ZA200903278B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116057049A (zh) 2020-05-29 2023-05-02 大邱庆北尖端医疗产业振兴财团 甲酰胺衍生物和含其作为活性成分的用于预防或治疗精神疾病的药物组合物
WO2021241875A1 (ko) 2020-05-29 2021-12-02 재단법인 대구경북첨단의료산업진흥재단 설폰아미드 유도체 및 이를 유효성분으로 함유하는 정신질환의 예방 또는 치료용 약학적 조성물
KR102397705B1 (ko) 2020-05-29 2022-05-13 재단법인 대구경북첨단의료산업진흥재단 N을 하나 이상 포함하는 5원자의 헤테로아릴 유도체 및 이를 유효성분으로 함유하는 정신질환의 예방 또는 치료용 약학적 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602005025785D1 (de) * 2004-09-30 2011-02-17 Neurosearch As Neue chromen-2-one derivate und ihre verwendung als monoamineneurotransmitter-wiederaufnahmeinhibitoren

Also Published As

Publication number Publication date
CN101563344A (zh) 2009-10-21
DK2121677T3 (da) 2011-02-07
NZ577071A (en) 2011-07-29
CN101563344B (zh) 2011-11-16
PT2121677E (pt) 2011-01-25
TW200836732A (en) 2008-09-16
DE602007010356D1 (de) 2010-12-16
AR064457A1 (es) 2009-04-01
KR20090089439A (ko) 2009-08-21
RU2009119919A (ru) 2011-01-27
ATE486868T1 (de) 2010-11-15
BRPI0719578A2 (pt) 2013-12-17

Similar Documents

Publication Publication Date Title
GB0700919D0 (en) Degradable compositions, apparatus comprising same, and methods of use
ZA200806145B (en) Cycloalkylamines as monoamine reuptake inhibitors
IL195619A0 (en) Compositions and methods for joininig non-conjoined iumens
PL2040728T3 (pl) FKBP-L i jego zastosowanie jako inhibitora angiogenezy
ZA200807447B (en) Thieno-Pyridine derivatives as MEK inhibitors
EP1978961A4 (en) MONOAMINE RECORDING INHIBITORS ON TETRALON BASIS
GB0601143D0 (en) Uses, methods and compositions
HK1137756A1 (en) Substituted dihydropyrazolones and use thereof as hif-prolyl-4 -hydroxylase inhibitors hif--4-
HK1138616A1 (en) Novel laccases, compositions and methods of use
PL2078001T3 (pl) Pochodne diazepano-acetamidowe jako selektywne inhibitory 11-hsd1
EP2239261A4 (en) PYRROLOPYRIMIDINE DERIVATIVE FOR USE AS A PI3K INHIBITOR AND USE THEREOF
EP2101731A4 (en) PROCESSES AND COMPOSITIONS WITH END OXIFES
IL197528A0 (en) Synthesis, methods of using, and compositions of cycloalkylmethylamines
IL196000A0 (en) 2-arylindole derivatives as npges-i inhibitors
IL209406A0 (en) Novel tetramethyl substituted piperidine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
IL192485A0 (en) Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
GB0617171D0 (en) Novel compositions and methods
EP2088865A4 (en) METHODS AND COMPOSITIONS AROUND GUGGULPHOSPHOLIPIDS
IL195014A0 (en) Benzazepine derivatives as monoamine reuptake inhibitors
HK1112918A1 (en) Benzofuranyl derivatives as 5-ht6-receptor inhibitors
ZA200806434B (en) Calcium-enrichment compositions and methods for production thereof
IL198762A0 (en) Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
ZA200903278B (en) Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
IL180777A0 (en) Novel chromen-2- one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
IL178734A0 (en) Novel alkyl substituted piperazine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors