ZA200903041B - Combination - Google Patents

Combination

Info

Publication number
ZA200903041B
ZA200903041B ZA200903041A ZA200903041A ZA200903041B ZA 200903041 B ZA200903041 B ZA 200903041B ZA 200903041 A ZA200903041 A ZA 200903041A ZA 200903041 A ZA200903041 A ZA 200903041A ZA 200903041 B ZA200903041 B ZA 200903041B
Authority
ZA
South Africa
Prior art keywords
combination
Prior art date
Application number
ZA200903041A
Other languages
English (en)
Inventor
Peter Wisdom Atadja
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39272127&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200903041(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ZA200903041B publication Critical patent/ZA200903041B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200903041A 2006-12-04 2009-05-04 Combination ZA200903041B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86838806P 2006-12-04 2006-12-04

Publications (1)

Publication Number Publication Date
ZA200903041B true ZA200903041B (en) 2010-03-31

Family

ID=39272127

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200903041A ZA200903041B (en) 2006-12-04 2009-05-04 Combination

Country Status (26)

Country Link
US (1) US8093220B2 (ja)
EP (1) EP2099451B1 (ja)
JP (3) JP5784274B2 (ja)
KR (1) KR101475538B1 (ja)
CN (1) CN101553223A (ja)
AR (1) AR064072A1 (ja)
AU (1) AU2007328281B2 (ja)
BR (1) BRPI0719746A2 (ja)
CA (1) CA2670741C (ja)
CL (1) CL2007003467A1 (ja)
EC (1) ECSP099483A (ja)
ES (1) ES2569477T3 (ja)
GT (1) GT200900148A (ja)
HK (1) HK1132462A1 (ja)
IL (1) IL198638A (ja)
MA (1) MA30982B1 (ja)
MX (1) MX2009005946A (ja)
MY (1) MY148893A (ja)
NO (1) NO20092473L (ja)
PE (1) PE20081303A1 (ja)
PL (1) PL2099451T3 (ja)
RU (1) RU2469717C2 (ja)
TN (1) TN2009000213A1 (ja)
TW (1) TW200831075A (ja)
WO (1) WO2008070011A2 (ja)
ZA (1) ZA200903041B (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2519474T3 (es) * 2008-03-26 2014-11-07 Novartis Ag Inhibidores de las desacetilasas B basados en hidroxamato
WO2010009285A1 (en) * 2008-07-18 2010-01-21 Novartis Ag Use of hdac inhibitors for the treatment of acute myeloid leukemia and/or myelodysplastic syndrome
BRPI0915927A2 (pt) * 2008-07-18 2016-06-07 Novartis Ag uso de inibiodores de hdac para o tratamento da doença de hodgkin
US20110053925A1 (en) * 2009-08-28 2011-03-03 Novartis Ag Hydroxamate-Based Inhibitors of Deacetylases
RU2016103126A (ru) * 2010-06-07 2018-11-22 АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи Способы комбинированной терапии для лечения пролиферативных заболеваний
KR20130101519A (ko) * 2010-09-01 2013-09-13 노파르티스 아게 Hdac 억제제와 혈소판감소증 약물의 조합물
WO2014164708A1 (en) * 2013-03-12 2014-10-09 Quanticel Pharmaceuticals, Inc. Histone dementhylase inhibitors
CN105960239A (zh) 2013-11-27 2016-09-21 翁科埃斯克斯有限公司 利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法
KR20170048601A (ko) 2014-09-17 2017-05-08 셀젠 콴티셀 리서치, 인크. 히스톤 탈메틸효소 억제제
SG11201707418WA (en) 2015-03-13 2017-10-30 Forma Therapeutics Inc Alpha-cinnamide compounds and compositions as hdac8 inhibitors
US10537585B2 (en) 2017-12-18 2020-01-21 Dexcel Pharma Technologies Ltd. Compositions comprising dexamethasone

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020354A1 (es) * 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
US6905669B2 (en) * 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
JP2006528952A (ja) * 2003-05-21 2006-12-28 ノバルティス アクチエンゲゼルシャフト ヒストンデアセチラーゼ阻害剤と化学療法剤の組み合わせ

Also Published As

Publication number Publication date
ES2569477T3 (es) 2016-05-11
MY148893A (en) 2013-06-14
JP2016006070A (ja) 2016-01-14
HK1132462A1 (zh) 2010-02-26
US20100069318A1 (en) 2010-03-18
PL2099451T3 (pl) 2016-07-29
JP5784274B2 (ja) 2015-09-24
US8093220B2 (en) 2012-01-10
KR101475538B1 (ko) 2014-12-22
ECSP099483A (es) 2009-08-28
RU2009125439A (ru) 2011-01-20
IL198638A (en) 2015-06-30
TW200831075A (en) 2008-08-01
GT200900148A (es) 2011-08-02
KR20090087115A (ko) 2009-08-14
WO2008070011A2 (en) 2008-06-12
CL2007003467A1 (es) 2008-07-11
EP2099451B1 (en) 2016-02-10
JP2010511702A (ja) 2010-04-15
PE20081303A1 (es) 2008-10-28
AR064072A1 (es) 2009-03-11
JP2014097992A (ja) 2014-05-29
MA30982B1 (fr) 2009-12-01
CN101553223A (zh) 2009-10-07
WO2008070011A3 (en) 2008-07-24
RU2469717C2 (ru) 2012-12-20
IL198638A0 (en) 2010-02-17
BRPI0719746A2 (pt) 2013-12-10
CA2670741C (en) 2016-04-12
EP2099451A2 (en) 2009-09-16
TN2009000213A1 (en) 2010-10-18
CA2670741A1 (en) 2008-06-12
AU2007328281A1 (en) 2008-06-12
NO20092473L (no) 2009-09-01
MX2009005946A (es) 2009-06-17
AU2007328281B2 (en) 2011-03-31

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