ZA200809110B - Combination of alovudine and zidovudine in a molar ratio of 1:100 to 1:350 - Google Patents

Combination of alovudine and zidovudine in a molar ratio of 1:100 to 1:350

Info

Publication number
ZA200809110B
ZA200809110B ZA200809110A ZA200809110A ZA200809110B ZA 200809110 B ZA200809110 B ZA 200809110B ZA 200809110 A ZA200809110 A ZA 200809110A ZA 200809110 A ZA200809110 A ZA 200809110A ZA 200809110 B ZA200809110 B ZA 200809110B
Authority
ZA
South Africa
Prior art keywords
alovudine
zidovudine
molar ratio
combination
administration
Prior art date
Application number
ZA200809110A
Other languages
English (en)
Inventor
Zhang Hong
Oberg Bo
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir Ab filed Critical Medivir Ab
Publication of ZA200809110B publication Critical patent/ZA200809110B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31678—Of metal
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31855—Of addition polymer from unsaturated monomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200809110A 2006-05-05 2008-10-23 Combination of alovudine and zidovudine in a molar ratio of 1:100 to 1:350 ZA200809110B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0608876.9A GB0608876D0 (en) 2006-05-05 2006-05-05 Combination therapy

Publications (1)

Publication Number Publication Date
ZA200809110B true ZA200809110B (en) 2009-08-26

Family

ID=36603961

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200809110A ZA200809110B (en) 2006-05-05 2008-10-23 Combination of alovudine and zidovudine in a molar ratio of 1:100 to 1:350

Country Status (19)

Country Link
US (3) US20090170806A1 (es)
EP (1) EP2015759B1 (es)
JP (1) JP2009536192A (es)
CN (1) CN101437525B (es)
AT (1) ATE476187T1 (es)
AU (1) AU2007246644B2 (es)
BR (1) BRPI0710730A2 (es)
CA (1) CA2651232C (es)
DE (1) DE602007008226D1 (es)
DK (1) DK2015759T3 (es)
EA (1) EA014778B1 (es)
ES (1) ES2349486T3 (es)
GB (1) GB0608876D0 (es)
HK (1) HK1132651A1 (es)
MX (1) MX2008013491A (es)
PL (1) PL2015759T3 (es)
PT (1) PT2015759E (es)
WO (1) WO2007129274A2 (es)
ZA (1) ZA200809110B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130337453A1 (en) * 2010-10-21 2013-12-19 Tufts University Extracellular mitochondria-based screening and treatment

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
SE464168B (sv) * 1989-07-19 1991-03-18 Bo Fredrik Oeberg Antiviral komposition bestaaende av en 3'-fluoro-2',3'-dideoxynukleosidfoerening och en 2',3'-dideoxynukleosidfoerening (exempelvis azt)
DE69128626T2 (de) * 1990-07-19 1998-05-20 The Wellcome Foundation Ltd., Greenford Enzyminaktivatoren
ATE138927T1 (de) 1990-08-06 1996-06-15 American Cyanamid Co Verfahren zur herstellung von desoxynukleosiden
DE4026265A1 (de) 1990-08-20 1992-02-27 Boehringer Mannheim Gmbh Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
EP0698032B1 (en) 1993-05-12 1998-07-29 Rhodia Limited Preparation of fluoro-nucleosides and intermediates for use therein
DE4402492A1 (de) 1994-01-28 1995-08-03 Boehringer Mannheim Gmbh Verfahren zur Herstellung von unsymmetrischen Phosphorsäurediestern
DE4418690A1 (de) 1994-05-28 1996-01-11 Boehringer Mannheim Gmbh Neue Lipidester von Nucleosid-Monophosphaten und deren Verwendung als immunsuppressive Arzneimittel
JP2002502826A (ja) * 1998-02-09 2002-01-29 アヴェンティス ファーマシューティカルズ プロダクツ インコーポレイテッド Ｈｉｖ感染の治療用組成物および方法
SE0100733D0 (sv) 2001-03-05 2001-03-05 Medivir Ab Non-nucleoside reverse transcriptase inhibitors
US20060084627A1 (en) 2002-06-27 2006-04-20 Medivir Ab Synergistic interaction of abacavir and alovudine
WO2004087140A1 (en) * 2003-03-27 2004-10-14 Boehringer Ingelheim International Gmbh Antiviral combination of a dipyridodiazepinone and a further antiretroviral compound
AU2004312284B2 (en) 2004-01-08 2010-08-05 Medivir Ab Non-nucleotide reverse transcriptase inhibitors

Also Published As

Publication number Publication date
GB0608876D0 (en) 2006-06-14
HK1132651A1 (en) 2010-03-05
WO2007129274A3 (en) 2008-03-06
BRPI0710730A2 (pt) 2012-03-13
CN101437525B (zh) 2011-11-23
CA2651232C (en) 2013-12-31
DK2015759T3 (da) 2010-11-15
MX2008013491A (es) 2008-10-29
EP2015759B1 (en) 2010-08-04
WO2007129274A2 (en) 2007-11-15
US20120115807A1 (en) 2012-05-10
US20130217646A1 (en) 2013-08-22
EA014778B1 (ru) 2011-02-28
US20090170806A1 (en) 2009-07-02
JP2009536192A (ja) 2009-10-08
AU2007246644B2 (en) 2010-09-30
DE602007008226D1 (de) 2010-09-16
PT2015759E (pt) 2010-10-28
AU2007246644A1 (en) 2007-11-15
CA2651232A1 (en) 2007-11-15
WO2007129274A9 (en) 2009-03-12
CN101437525A (zh) 2009-05-20
EA200870501A1 (ru) 2009-04-28
ES2349486T3 (es) 2011-01-04
EP2015759A2 (en) 2009-01-21
ATE476187T1 (de) 2010-08-15
PL2015759T3 (pl) 2011-01-31

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