ZA200807600B - Pharmaceutical composition containing GHRP-6 capable of preventing and elimanting fibrosis and other forms of pathological deposit in tissue - Google Patents
Pharmaceutical composition containing GHRP-6 capable of preventing and elimanting fibrosis and other forms of pathological deposit in tissueInfo
- Publication number
- ZA200807600B ZA200807600B ZA200807600A ZA200807600A ZA200807600B ZA 200807600 B ZA200807600 B ZA 200807600B ZA 200807600 A ZA200807600 A ZA 200807600A ZA 200807600 A ZA200807600 A ZA 200807600A ZA 200807600 B ZA200807600 B ZA 200807600B
- Authority
- ZA
- South Africa
- Prior art keywords
- elimanting
- fibrosis
- tissue
- preventing
- forms
- Prior art date
Links
- WZHKXNSOCOQYQX-FUAFALNISA-N (2s)-6-amino-2-[[(2r)-2-[[(2s)-2-[[(2s)-2-[[(2r)-2-[[(2s)-2-amino-3-(1h-imidazol-5-yl)propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1h-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide Chemical compound C([C@H](N)C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(N)=O)C1=CN=CN1 WZHKXNSOCOQYQX-FUAFALNISA-N 0.000 title 1
- 206010016654 Fibrosis Diseases 0.000 title 1
- 230000004761 fibrosis Effects 0.000 title 1
- 108010015153 growth hormone releasing hexapeptide Proteins 0.000 title 1
- 230000001575 pathological effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF], i.e. somatoliberin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20060048A CU23592A1 (es) | 2006-02-28 | 2006-02-28 | Método para prevenir y eliminar las fibrosis y otras formas de depósito patológico en los tejidos aplicando el péptido secretagogo ghrp-6 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200807600B true ZA200807600B (en) | 2009-06-24 |
Family
ID=37964643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200807600A ZA200807600B (en) | 2006-02-28 | 2008-09-03 | Pharmaceutical composition containing GHRP-6 capable of preventing and elimanting fibrosis and other forms of pathological deposit in tissue |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US20090221512A1 (fr) |
| EP (2) | EP2368563A1 (fr) |
| JP (1) | JP5426175B2 (fr) |
| KR (1) | KR101462077B1 (fr) |
| CN (1) | CN101426517B (fr) |
| AR (1) | AR059644A1 (fr) |
| AU (1) | AU2007219568B2 (fr) |
| BR (1) | BRPI0708349B8 (fr) |
| CA (1) | CA2644431C (fr) |
| CU (1) | CU23592A1 (fr) |
| DK (1) | DK1994939T3 (fr) |
| ES (1) | ES2388879T3 (fr) |
| MX (1) | MX2008011140A (fr) |
| RU (1) | RU2465913C2 (fr) |
| WO (1) | WO2007098715A1 (fr) |
| ZA (1) | ZA200807600B (fr) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008121767A2 (fr) | 2007-03-28 | 2008-10-09 | President And Fellows Of Harvard College | Polypeptides cousus |
| WO2012021876A2 (fr) | 2010-08-13 | 2012-02-16 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques |
| AU2012326026B2 (en) | 2011-10-18 | 2017-04-13 | Aileron Therapeutics, Inc. | Peptidomimetic macrocyles |
| KR102112373B1 (ko) | 2012-02-15 | 2020-05-18 | 에일러론 테라퓨틱스 인코포레이티드 | 펩티드모방체 마크로사이클 |
| US8987414B2 (en) | 2012-02-15 | 2015-03-24 | Aileron Therapeutics, Inc. | Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles |
| KR101667383B1 (ko) * | 2012-03-28 | 2016-10-18 | 주식회사 인코스팜 | 비오틴이 결합된 ｈｅｘａｐｅｐｔｉｄｅ-２ 유도체 및 이의 용도 |
| SG11201503052RA (en) | 2012-11-01 | 2015-05-28 | Aileron Therapeutics Inc | Disubstituted amino acids and methods of preparation and use thereof |
| KR102051433B1 (ko) * | 2013-08-27 | 2020-01-08 | (주)네오팜 | 근육 분화 촉진 및 근육 강화용 조성물 및 외용제 |
| US9119832B2 (en) * | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
| WO2016049359A1 (fr) | 2014-09-24 | 2016-03-31 | Aileron Therapeutics, Inc. | Macrocycles peptidomimétiques et leurs utilisations |
| AU2016235424A1 (en) | 2015-03-20 | 2017-10-05 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
| FR3034662B1 (fr) * | 2015-04-10 | 2020-08-28 | Isp Investments Inc | Nouvelles utilisations du peptide de sequence his-d-trp-ala-trp-d-phe-lys-nh2 pour diminuer ou retarder l'apparition de la senescence cellulaire et des signes du vieillissement cutane |
| CN106730414B (zh) * | 2015-12-30 | 2017-10-10 | 南京中硼联康医疗科技有限公司 | 用于消除β淀粉样蛋白的中子捕获治疗系统 |
| CN109908331A (zh) * | 2019-04-30 | 2019-06-21 | 青岛大学附属医院 | 海沙瑞林在制备保护肾脏缺血再灌注损伤药物/药物组合物中的应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4411890A (en) * | 1981-04-14 | 1983-10-25 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
| TW432073B (en) * | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
| DE60022683D1 (de) * | 1999-12-28 | 2005-10-20 | Kaken Pharma Co Ltd | Nervenschutzmittel |
| CU23157A1 (es) * | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
| AU2002349485A1 (en) * | 2001-12-07 | 2003-06-17 | Kaken Pharmaceutical Co., Ltd. | Cell migration inhibitor |
| TWI331922B (en) * | 2002-08-09 | 2010-10-21 | Ipsen Pharma Sas | Growth hormone releasing peptides |
| AU2004233705C1 (en) * | 2003-04-30 | 2010-04-01 | Kenji Kangawa | Preventives or remedies for hepatopathy |
| JP2005239712A (ja) * | 2004-01-30 | 2005-09-08 | Kaken Pharmaceut Co Ltd | 神経突起伸展剤 |
| WO2005112903A2 (fr) * | 2004-05-14 | 2005-12-01 | Novo Nordisk A/S | Utilisation d'antagonistes de la ghrelin pour le traitement de certaines maladies du systeme nerveux central |
-
2006
- 2006-02-28 CU CU20060048A patent/CU23592A1/es unknown
-
2007
- 2007-02-23 BR BRPI0708349A patent/BRPI0708349B8/pt active IP Right Grant
- 2007-02-23 JP JP2008556642A patent/JP5426175B2/ja not_active Expired - Fee Related
- 2007-02-23 CN CN2007800140575A patent/CN101426517B/zh active Active
- 2007-02-23 AU AU2007219568A patent/AU2007219568B2/en active Active
- 2007-02-23 CA CA2644431A patent/CA2644431C/fr active Active
- 2007-02-23 DK DK07711099.7T patent/DK1994939T3/da active
- 2007-02-23 EP EP11170318A patent/EP2368563A1/fr not_active Withdrawn
- 2007-02-23 WO PCT/CU2007/000005 patent/WO2007098715A1/fr active Application Filing
- 2007-02-23 EP EP07711099A patent/EP1994939B1/fr active Active
- 2007-02-23 MX MX2008011140A patent/MX2008011140A/es active IP Right Grant
- 2007-02-23 KR KR1020087023744A patent/KR101462077B1/ko active IP Right Grant
- 2007-02-23 ES ES07711099T patent/ES2388879T3/es active Active
- 2007-02-23 RU RU2008138561/15A patent/RU2465913C2/ru not_active Application Discontinuation
- 2007-02-23 US US12/281,018 patent/US20090221512A1/en not_active Abandoned
- 2007-02-27 AR ARP070100804A patent/AR059644A1/es unknown
-
2008
- 2008-09-03 ZA ZA200807600A patent/ZA200807600B/xx unknown
-
2011
- 2011-06-01 US US13/150,526 patent/US8722626B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1994939A1 (fr) | 2008-11-26 |
| KR101462077B1 (ko) | 2014-11-20 |
| KR20080100378A (ko) | 2008-11-17 |
| BRPI0708349A2 (pt) | 2011-05-24 |
| US8722626B2 (en) | 2014-05-13 |
| RU2465913C2 (ru) | 2012-11-10 |
| RU2008138561A (ru) | 2010-04-10 |
| JP5426175B2 (ja) | 2014-02-26 |
| DK1994939T3 (da) | 2012-09-10 |
| US20110230415A1 (en) | 2011-09-22 |
| CU23592A1 (es) | 2010-11-11 |
| CA2644431C (fr) | 2016-08-30 |
| AR059644A1 (es) | 2008-04-16 |
| MX2008011140A (es) | 2008-09-08 |
| AU2007219568A1 (en) | 2007-09-07 |
| JP2009528302A (ja) | 2009-08-06 |
| US20090221512A1 (en) | 2009-09-03 |
| AU2007219568B2 (en) | 2012-10-04 |
| EP2368563A1 (fr) | 2011-09-28 |
| BRPI0708349B8 (pt) | 2021-05-25 |
| ES2388879T3 (es) | 2012-10-19 |
| WO2007098715A1 (fr) | 2007-09-07 |
| CA2644431A1 (fr) | 2007-09-07 |
| CN101426517A (zh) | 2009-05-06 |
| EP1994939B1 (fr) | 2012-05-30 |
| CN101426517B (zh) | 2013-04-03 |
| BRPI0708349B1 (pt) | 2019-04-24 |
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